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Journal Abstract Search

228 related items for PubMed ID: 21549800

  • 1. Trichloroacetic acid: updated estimates of its bioavailability and its contribution to trichloroethylene-induced mouse hepatomegaly.
    Chiu WA.
    Toxicology; 2011 Jul 29; 285(3):114-25. PubMed ID: 21549800
    [Abstract] [Full Text] [Related]

  • 2. Development of an updated PBPK model for trichloroethylene and metabolites in mice, and its application to discern the role of oxidative metabolism in TCE-induced hepatomegaly.
    Evans MV, Chiu WA, Okino MS, Caldwell JC.
    Toxicol Appl Pharmacol; 2009 May 01; 236(3):329-40. PubMed ID: 19249323
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  • 3. A physiologically based pharmacokinetic model for trichloroethylene and its metabolites, chloral hydrate, trichloroacetate, dichloroacetate, trichloroethanol, and trichloroethanol glucuronide in B6C3F1 mice.
    Abbas R, Fisher JW.
    Toxicol Appl Pharmacol; 1997 Nov 01; 147(1):15-30. PubMed ID: 9356303
    [Abstract] [Full Text] [Related]

  • 4. Contribution of trichloroacetic acid to liver tumors observed in perchloroethylene (perc)-exposed mice.
    Sweeney LM, Kirman CR, Gargas ML, Dugard PH.
    Toxicology; 2009 Jun 16; 260(1-3):77-83. PubMed ID: 19464572
    [Abstract] [Full Text] [Related]

  • 5. Bayesian population analysis of a harmonized physiologically based pharmacokinetic model of trichloroethylene and its metabolites.
    Hack CE, Chiu WA, Jay Zhao Q, Clewell HJ.
    Regul Toxicol Pharmacol; 2006 Oct 16; 46(1):63-83. PubMed ID: 16889879
    [Abstract] [Full Text] [Related]

  • 6. Trichloroethylene cancer risk: simplified calculation of PBPK-based MCLs for cytotoxic end points.
    Bogen KT, Gold LS.
    Regul Toxicol Pharmacol; 1997 Feb 16; 25(1):26-42. PubMed ID: 9056499
    [Abstract] [Full Text] [Related]

  • 7. Physiologically based pharmacokinetic modeling of inhaled trichloroethylene and its oxidative metabolites in B6C3F1 mice.
    Greenberg MS, Burton GA, Fisher JW.
    Toxicol Appl Pharmacol; 1999 Feb 01; 154(3):264-78. PubMed ID: 9931286
    [Abstract] [Full Text] [Related]

  • 8. Pharmacokinetic modeling of trichloroethylene and trichloroacetic acid in humans.
    Allen BC, Fisher JW.
    Risk Anal; 1993 Feb 01; 13(1):71-86. PubMed ID: 8451462
    [Abstract] [Full Text] [Related]

  • 9. Role of the peroxisome proliferator-activated receptor alpha (PPARalpha) in responses to trichloroethylene and metabolites, trichloroacetate and dichloroacetate in mouse liver.
    Laughter AR, Dunn CS, Swanson CL, Howroyd P, Cattley RC, Corton JC.
    Toxicology; 2004 Oct 15; 203(1-3):83-98. PubMed ID: 15363585
    [Abstract] [Full Text] [Related]

  • 10. Interactions in the tumor-promoting activity of carbon tetrachloride, trichloroacetate, and dichloroacetate in the liver of male B6C3F1 mice.
    Bull RJ, Sasser LB, Lei XC.
    Toxicology; 2004 Jul 01; 199(2-3):169-83. PubMed ID: 15147791
    [Abstract] [Full Text] [Related]

  • 11. Trichloroethylene risk assessment: a review and commentary.
    Jollow DJ, Bruckner JV, McMillan DC, Fisher JW, Hoel DG, Mohr LC.
    Crit Rev Toxicol; 2009 Jul 01; 39(9):782-97. PubMed ID: 19852561
    [Abstract] [Full Text] [Related]

  • 12. Physiologically based pharmacokinetic modeling of the pregnant rat: a multiroute exposure model for trichloroethylene and its metabolite, trichloroacetic acid.
    Fisher JW, Whittaker TA, Taylor DH, Clewell HJ, Andersen ME.
    Toxicol Appl Pharmacol; 1989 Jul 01; 99(3):395-414. PubMed ID: 2749729
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  • 16. The extent of dichloroacetate formation from trichloroethylene, chloral hydrate, trichloroacetate, and trichloroethanol in B6C3F1 mice.
    Merdink JL, Gonzalez-Leon A, Bull RJ, Schultz IR.
    Toxicol Sci; 1998 Sep 01; 45(1):33-41. PubMed ID: 9848108
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  • 17. Dose-dependent liver regeneration in chloroform, trichloroethylene and allyl alcohol ternary mixture hepatotoxicity in rats.
    Anand SS, Mumtaz MM, Mehendale HM.
    Arch Toxicol; 2005 Nov 01; 79(11):671-82. PubMed ID: 15940471
    [Abstract] [Full Text] [Related]

  • 18. Characterizing uncertainty and population variability in the toxicokinetics of trichloroethylene and metabolites in mice, rats, and humans using an updated database, physiologically based pharmacokinetic (PBPK) model, and Bayesian approach.
    Chiu WA, Okino MS, Evans MV.
    Toxicol Appl Pharmacol; 2009 Nov 15; 241(1):36-60. PubMed ID: 19660485
    [Abstract] [Full Text] [Related]

  • 19. Cardiogenic effects of trichloroethylene and trichloroacetic acid following exposure during heart specification of avian development.
    Drake VJ, Koprowski SL, Hu N, Smith SM, Lough J.
    Toxicol Sci; 2006 Nov 15; 94(1):153-62. PubMed ID: 16917067
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