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562 related items for PubMed ID: 21550972

  • 1. L-threonine regulates G1/S phase transition of mouse embryonic stem cells via PI3K/Akt, MAPKs, and mTORC pathways.
    Ryu JM, Han HJ.
    J Biol Chem; 2011 Jul 08; 286(27):23667-78. PubMed ID: 21550972
    [Abstract] [Full Text] [Related]

  • 2. Longitudinal inhibition of PI3K/Akt/mTOR signaling by LY294002 and rapamycin induces growth arrest of adult T-cell leukemia cells.
    Ikezoe T, Nishioka C, Bandobashi K, Yang Y, Kuwayama Y, Adachi Y, Takeuchi T, Koeffler HP, Taguchi H.
    Leuk Res; 2007 May 08; 31(5):673-82. PubMed ID: 17007924
    [Abstract] [Full Text] [Related]

  • 3. G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells.
    Gao N, Flynn DC, Zhang Z, Zhong XS, Walker V, Liu KJ, Shi X, Jiang BH.
    Am J Physiol Cell Physiol; 2004 Aug 08; 287(2):C281-91. PubMed ID: 15028555
    [Abstract] [Full Text] [Related]

  • 4. Dual inhibition of phosphatidylinositol 3-kinase/Akt and mammalian target of rapamycin signaling in human nonsmall cell lung cancer cells by a dietary flavonoid fisetin.
    Khan N, Afaq F, Khusro FH, Mustafa Adhami V, Suh Y, Mukhtar H.
    Int J Cancer; 2012 Apr 01; 130(7):1695-705. PubMed ID: 21618507
    [Abstract] [Full Text] [Related]

  • 5. Feedback loops blockade potentiates apoptosis induction and antitumor activity of a novel AKT inhibitor DC120 in human liver cancer.
    Yang F, Deng R, Qian XJ, Chang SH, Wu XQ, Qin J, Feng GK, Ding K, Zhu XF.
    Cell Death Dis; 2014 Mar 13; 5(3):e1114. PubMed ID: 24625973
    [Abstract] [Full Text] [Related]

  • 6. Short-period hypoxia increases mouse embryonic stem cell proliferation through cooperation of arachidonic acid and PI3K/Akt signalling pathways.
    Lee SH, Lee MY, Han HJ.
    Cell Prolif; 2008 Apr 13; 41(2):230-47. PubMed ID: 18336469
    [Abstract] [Full Text] [Related]

  • 7. Zinc chloride stimulates DNA synthesis of mouse embryonic stem cells: involvement of PI3K/Akt, MAPKs, and mTOR.
    Ryu JM, Lee MY, Yun SP, Han HJ.
    J Cell Physiol; 2009 Mar 13; 218(3):558-67. PubMed ID: 18988195
    [Abstract] [Full Text] [Related]

  • 8. Strain-induced vascular endothelial cell proliferation requires PI3K-dependent mTOR-4E-BP1 signal pathway.
    Li W, Sumpio BE.
    Am J Physiol Heart Circ Physiol; 2005 Apr 13; 288(4):H1591-7. PubMed ID: 15591103
    [Abstract] [Full Text] [Related]

  • 9. Prolactin activates mammalian target-of-rapamycin through phosphatidylinositol 3-kinase and stimulates phosphorylation of p70S6K and 4E-binding protein-1 in lymphoma cells.
    Bishop JD, Nien WL, Dauphinee SM, Too CK.
    J Endocrinol; 2006 Aug 13; 190(2):307-12. PubMed ID: 16899564
    [Abstract] [Full Text] [Related]

  • 10. Rapamycin promotes the osteoblastic differentiation of human embryonic stem cells by blocking the mTOR pathway and stimulating the BMP/Smad pathway.
    Lee KW, Yook JY, Son MY, Kim MJ, Koo DB, Han YM, Cho YS.
    Stem Cells Dev; 2010 Apr 13; 19(4):557-68. PubMed ID: 19642865
    [Abstract] [Full Text] [Related]

  • 11. MicroRNA-29b Inhibits Angiogenesis by Targeting VEGFA through the MAPK/ERK and PI3K/Akt Signaling Pathways in Endometrial Carcinoma.
    Chen HX, Xu XX, Tan BZ, Zhang Z, Zhou XD.
    Cell Physiol Biochem; 2017 Apr 13; 41(3):933-946. PubMed ID: 28222438
    [Abstract] [Full Text] [Related]

  • 12. PI3K-FRAP/mTOR pathway is critical for hepatocyte proliferation whereas MEK/ERK supports both proliferation and survival.
    Coutant A, Rescan C, Gilot D, Loyer P, Guguen-Guillouzo C, Baffet G.
    Hepatology; 2002 Nov 13; 36(5):1079-88. PubMed ID: 12395317
    [Abstract] [Full Text] [Related]

  • 13. Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway.
    Marzec M, Kasprzycka M, Liu X, El-Salem M, Halasa K, Raghunath PN, Bucki R, Wlodarski P, Wasik MA.
    Oncogene; 2007 Aug 16; 26(38):5606-14. PubMed ID: 17353907
    [Abstract] [Full Text] [Related]

  • 14. Fibronectin stimulates non-small cell lung carcinoma cell growth through activation of Akt/mammalian target of rapamycin/S6 kinase and inactivation of LKB1/AMP-activated protein kinase signal pathways.
    Han S, Khuri FR, Roman J.
    Cancer Res; 2006 Jan 01; 66(1):315-23. PubMed ID: 16397245
    [Abstract] [Full Text] [Related]

  • 15. S6K1 and 4E-BP1 are independent regulated and control cellular growth in bladder cancer.
    Nawroth R, Stellwagen F, Schulz WA, Stoehr R, Hartmann A, Krause BJ, Gschwend JE, Retz M.
    PLoS One; 2011 Jan 01; 6(11):e27509. PubMed ID: 22110663
    [Abstract] [Full Text] [Related]

  • 16. Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility.
    Gulati N, Karsy M, Albert L, Murali R, Jhanwar-Uniyal M.
    Int J Oncol; 2009 Oct 01; 35(4):731-40. PubMed ID: 19724909
    [Abstract] [Full Text] [Related]

  • 17. Rapamycin attenuates BAFF-extended proliferation and survival via disruption of mTORC1/2 signaling in normal and neoplastic B-lymphoid cells.
    Zeng Q, Qin S, Zhang H, Liu B, Qin J, Wang X, Zhang R, Liu C, Dong X, Zhang S, Huang S, Chen L.
    J Cell Physiol; 2018 Jan 01; 233(1):516-529. PubMed ID: 28300280
    [Abstract] [Full Text] [Related]

  • 18. High glucose regulates cyclin D1/E of human mesenchymal stem cells through TGF-beta1 expression via Ca2+/PKC/MAPKs and PI3K/Akt/mTOR signal pathways.
    Ryu JM, Lee MY, Yun SP, Han HJ.
    J Cell Physiol; 2010 Jul 01; 224(1):59-70. PubMed ID: 20232305
    [Abstract] [Full Text] [Related]

  • 19. Increased AKT S473 phosphorylation after mTORC1 inhibition is rictor dependent and does not predict tumor cell response to PI3K/mTOR inhibition.
    Breuleux M, Klopfenstein M, Stephan C, Doughty CA, Barys L, Maira SM, Kwiatkowski D, Lane HA.
    Mol Cancer Ther; 2009 Apr 01; 8(4):742-53. PubMed ID: 19372546
    [Abstract] [Full Text] [Related]

  • 20. Signal pathways involved in activation of p70S6K and phosphorylation of 4E-BP1 following exposure of multiple myeloma tumor cells to interleukin-6.
    Shi Y, Hsu JH, Hu L, Gera J, Lichtenstein A.
    J Biol Chem; 2002 May 03; 277(18):15712-20. PubMed ID: 11872747
    [Abstract] [Full Text] [Related]


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