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202 related items for PubMed ID: 21557994

  • 1. The effect of deafness duration on neurotrophin gene therapy for spiral ganglion neuron protection.
    Wise AK, Tu T, Atkinson PJ, Flynn BO, Sgro BE, Hume C, O'Leary SJ, Shepherd RK, Richardson RT.
    Hear Res; 2011 Aug; 278(1-2):69-76. PubMed ID: 21557994
    [Abstract] [Full Text] [Related]

  • 2. Spiral ganglion neuron survival and function in the deafened cochlea following chronic neurotrophic treatment.
    Landry TG, Wise AK, Fallon JB, Shepherd RK.
    Hear Res; 2011 Dec; 282(1-2):303-13. PubMed ID: 21762764
    [Abstract] [Full Text] [Related]

  • 3. Effects of localized neurotrophin gene expression on spiral ganglion neuron resprouting in the deafened cochlea.
    Wise AK, Hume CR, Flynn BO, Jeelall YS, Suhr CL, Sgro BE, O'Leary SJ, Shepherd RK, Richardson RT.
    Mol Ther; 2010 Jun; 18(6):1111-22. PubMed ID: 20216530
    [Abstract] [Full Text] [Related]

  • 4. Neurotrophin gene therapy for sustained neural preservation after deafness.
    Atkinson PJ, Wise AK, Flynn BO, Nayagam BA, Hume CR, O'Leary SJ, Shepherd RK, Richardson RT.
    PLoS One; 2012 Jun; 7(12):e52338. PubMed ID: 23284995
    [Abstract] [Full Text] [Related]

  • 5. Chronic neurotrophin delivery promotes ectopic neurite growth from the spiral ganglion of deafened cochleae without compromising the spatial selectivity of cochlear implants.
    Landry TG, Fallon JB, Wise AK, Shepherd RK.
    J Comp Neurol; 2013 Aug 15; 521(12):2818-32. PubMed ID: 23436344
    [Abstract] [Full Text] [Related]

  • 6. Improved Auditory Nerve Survival with Nanoengineered Supraparticles for Neurotrophin Delivery into the Deafened Cochlea.
    Wise AK, Tan J, Wang Y, Caruso F, Shepherd RK.
    PLoS One; 2016 Aug 15; 11(10):e0164867. PubMed ID: 27788219
    [Abstract] [Full Text] [Related]

  • 7. Differential effects of AAV.BDNF and AAV.Ntf3 in the deafened adult guinea pig ear.
    Budenz CL, Wong HT, Swiderski DL, Shibata SB, Pfingst BE, Raphael Y.
    Sci Rep; 2015 Mar 02; 5():8619. PubMed ID: 25726967
    [Abstract] [Full Text] [Related]

  • 8. Development of a cell-based treatment for long-term neurotrophin expression and spiral ganglion neuron survival.
    Zanin MP, Hellström M, Shepherd RK, Harvey AR, Gillespie LN.
    Neuroscience; 2014 Sep 26; 277():690-9. PubMed ID: 25088914
    [Abstract] [Full Text] [Related]

  • 9. Neurotrophins and electrical stimulation for protection and repair of spiral ganglion neurons following sensorineural hearing loss.
    Shepherd RK, Coco A, Epp SB.
    Hear Res; 2008 Aug 26; 242(1-2):100-9. PubMed ID: 18243608
    [Abstract] [Full Text] [Related]

  • 10. Neurotrophin gene therapy to promote survival of spiral ganglion neurons after deafness.
    Leake PA, Akil O, Lang H.
    Hear Res; 2020 Sep 01; 394():107955. PubMed ID: 32331858
    [Abstract] [Full Text] [Related]

  • 11. AAV-Mediated Neurotrophin Gene Therapy Promotes Improved Survival of Cochlear Spiral Ganglion Neurons in Neonatally Deafened Cats: Comparison of AAV2-hBDNF and AAV5-hGDNF.
    Leake PA, Rebscher SJ, Dore' C, Akil O.
    J Assoc Res Otolaryngol; 2019 Aug 01; 20(4):341-361. PubMed ID: 31222416
    [Abstract] [Full Text] [Related]

  • 12. Connexin 26 null mice exhibit spiral ganglion degeneration that can be blocked by BDNF gene therapy.
    Takada Y, Beyer LA, Swiderski DL, O'Neal AL, Prieskorn DM, Shivatzki S, Avraham KB, Raphael Y.
    Hear Res; 2014 Mar 01; 309():124-35. PubMed ID: 24333301
    [Abstract] [Full Text] [Related]

  • 13. Viability of long-term gene therapy in the cochlea.
    Atkinson PJ, Wise AK, Flynn BO, Nayagam BA, Richardson RT.
    Sci Rep; 2014 Apr 22; 4():4733. PubMed ID: 24751795
    [Abstract] [Full Text] [Related]

  • 14. Neurotrophin Gene Therapy in Deafened Ears with Cochlear Implants: Long-term Effects on Nerve Survival and Functional Measures.
    Pfingst BE, Colesa DJ, Swiderski DL, Hughes AP, Strahl SB, Sinan M, Raphael Y.
    J Assoc Res Otolaryngol; 2017 Dec 22; 18(6):731-750. PubMed ID: 28776202
    [Abstract] [Full Text] [Related]

  • 15. Structural and Ultrastructural Changes to Type I Spiral Ganglion Neurons and Schwann Cells in the Deafened Guinea Pig Cochlea.
    Wise AK, Pujol R, Landry TG, Fallon JB, Shepherd RK.
    J Assoc Res Otolaryngol; 2017 Dec 22; 18(6):751-769. PubMed ID: 28717876
    [Abstract] [Full Text] [Related]

  • 16. Cochlear implants and ex vivo BDNF gene therapy protect spiral ganglion neurons.
    Rejali D, Lee VA, Abrashkin KA, Humayun N, Swiderski DL, Raphael Y.
    Hear Res; 2007 Jun 22; 228(1-2):180-7. PubMed ID: 17416474
    [Abstract] [Full Text] [Related]

  • 17. Postnatal expression of neurotrophic factors accessible to spiral ganglion neurons in the auditory system of adult hearing and deafened rats.
    Bailey EM, Green SH.
    J Neurosci; 2014 Sep 24; 34(39):13110-26. PubMed ID: 25253857
    [Abstract] [Full Text] [Related]

  • 18. Combining cell-based therapies and neural prostheses to promote neural survival.
    Wise AK, Fallon JB, Neil AJ, Pettingill LN, Geaney MS, Skinner SJ, Shepherd RK.
    Neurotherapeutics; 2011 Oct 24; 8(4):774-87. PubMed ID: 21904788
    [Abstract] [Full Text] [Related]

  • 19. Schwann cells genetically modified to express neurotrophins promote spiral ganglion neuron survival in vitro.
    Pettingill LN, Minter RL, Shepherd RK.
    Neuroscience; 2008 Mar 27; 152(3):821-8. PubMed ID: 18304740
    [Abstract] [Full Text] [Related]

  • 20. A single dose of neurotrophin-3 to the cochlea surrounds spiral ganglion neurons and provides trophic support.
    Richardson RT, O'Leary S, Wise A, Hardman J, Clark G.
    Hear Res; 2005 Jun 27; 204(1-2):37-47. PubMed ID: 15925190
    [Abstract] [Full Text] [Related]


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