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Journal Abstract Search

923 related items for PubMed ID: 21566061

  • 1. Hsp90 inhibitor-mediated disruption of chaperone association of ATR with hsp90 sensitizes cancer cells to DNA damage.
    Ha K, Fiskus W, Rao R, Balusu R, Venkannagari S, Nalabothula NR, Bhalla KN.
    Mol Cancer Ther; 2011 Jul; 10(7):1194-206. PubMed ID: 21566061
    [Abstract] [Full Text] [Related]

  • 2. Dissecting cellular responses to irradiation via targeted disruptions of the ATM-CHK1-PP2A circuit.
    Palii SS, Cui Y, Innes CL, Paules RS.
    Cell Cycle; 2013 Apr 01; 12(7):1105-18. PubMed ID: 23462183
    [Abstract] [Full Text] [Related]

  • 3. Ataxia telangiectasia and Rad3-related overexpressing cancer cells induce prolonged G₂ arrest and develop resistance to ionizing radiation.
    Kim YM, Lee YM, Park SY, Pyo H.
    DNA Cell Biol; 2011 Apr 01; 30(4):219-27. PubMed ID: 21294646
    [Abstract] [Full Text] [Related]

  • 4. ATR and Chk1 suppress a caspase-3-dependent apoptotic response following DNA replication stress.
    Myers K, Gagou ME, Zuazua-Villar P, Rodriguez R, Meuth M.
    PLoS Genet; 2009 Jan 01; 5(1):e1000324. PubMed ID: 19119425
    [Abstract] [Full Text] [Related]

  • 5. ATR-Chk2 signaling in p53 activation and DNA damage response during cisplatin-induced apoptosis.
    Pabla N, Huang S, Mi QS, Daniel R, Dong Z.
    J Biol Chem; 2008 Mar 07; 283(10):6572-83. PubMed ID: 18162465
    [Abstract] [Full Text] [Related]

  • 6. Requirement of MTA1 in ATR-mediated DNA damage checkpoint function.
    Li DQ, Ohshiro K, Khan MN, Kumar R.
    J Biol Chem; 2010 Jun 25; 285(26):19802-12. PubMed ID: 20427275
    [Abstract] [Full Text] [Related]

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  • 8. Novel HSP90 inhibitors, NVP-AUY922 and NVP-BEP800, radiosensitise tumour cells through cell-cycle impairment, increased DNA damage and repair protraction.
    Stingl L, Stühmer T, Chatterjee M, Jensen MR, Flentje M, Djuzenova CS.
    Br J Cancer; 2010 May 25; 102(11):1578-91. PubMed ID: 20502461
    [Abstract] [Full Text] [Related]

  • 9. Ataxia-telangiectasia-mutated (ATM) and NBS1-dependent phosphorylation of Chk1 on Ser-317 in response to ionizing radiation.
    Gatei M, Sloper K, Sorensen C, Syljuäsen R, Falck J, Hobson K, Savage K, Lukas J, Zhou BB, Bartek J, Khanna KK.
    J Biol Chem; 2003 Apr 25; 278(17):14806-11. PubMed ID: 12588868
    [Abstract] [Full Text] [Related]

  • 10. Hsp90α regulates ATM and NBN functions in sensing and repair of DNA double-strand breaks.
    Pennisi R, Antoccia A, Leone S, Ascenzi P, di Masi A.
    FEBS J; 2017 Aug 25; 284(15):2378-2395. PubMed ID: 28631426
    [Abstract] [Full Text] [Related]

  • 11. Rad9, Rad17, TopBP1 and claspin play essential roles in heat-induced activation of ATR kinase and heat tolerance.
    Tuul M, Kitao H, Iimori M, Matsuoka K, Kiyonari S, Saeki H, Oki E, Morita M, Maehara Y.
    PLoS One; 2013 Aug 25; 8(2):e55361. PubMed ID: 23383325
    [Abstract] [Full Text] [Related]

  • 12. Ataxia telangiectasia mutated (ATM) and ATM and Rad3-related protein exhibit selective target specificities in response to different forms of DNA damage.
    Helt CE, Cliby WA, Keng PC, Bambara RA, O'Reilly MA.
    J Biol Chem; 2005 Jan 14; 280(2):1186-92. PubMed ID: 15533933
    [Abstract] [Full Text] [Related]

  • 13. 90-kDa heat shock protein inhibition abrogates the topoisomerase I poison-induced G2/M checkpoint in p53-null tumor cells by depleting Chk1 and Wee1.
    Tse AN, Sheikh TN, Alan H, Chou TC, Schwartz GK.
    Mol Pharmacol; 2009 Jan 14; 75(1):124-33. PubMed ID: 18820127
    [Abstract] [Full Text] [Related]

  • 14. Chk1- and claspin-dependent but ATR/ATM- and Rad17-independent DNA replication checkpoint response in HeLa cells.
    Rodríguez-Bravo V, Guaita-Esteruelas S, Florensa R, Bachs O, Agell N.
    Cancer Res; 2006 Sep 01; 66(17):8672-9. PubMed ID: 16951182
    [Abstract] [Full Text] [Related]

  • 15. Hsp90 inhibitor NVP-AUY922 enhances radiation sensitivity of tumor cell lines under hypoxia.
    Djuzenova CS, Blassl C, Roloff K, Kuger S, Katzer A, Niewidok N, Günther N, Polat B, Sukhorukov VL, Flentje M.
    Cancer Biol Ther; 2012 Apr 01; 13(6):425-34. PubMed ID: 22286776
    [Abstract] [Full Text] [Related]

  • 16. Inhibition of ATR-dependent signaling by protoapigenone and its derivative sensitizes cancer cells to interstrand cross-link-generating agents in vitro and in vivo.
    Wang HC, Lee AY, Chou WC, Wu CC, Tseng CN, Liu KY, Lin WL, Chang FR, Chuang DW, Hunyadi A, Wu YC.
    Mol Cancer Ther; 2012 Jul 01; 11(7):1443-53. PubMed ID: 22532598
    [Abstract] [Full Text] [Related]

  • 17. DNA damage induced by temozolomide signals to both ATM and ATR: role of the mismatch repair system.
    Caporali S, Falcinelli S, Starace G, Russo MT, Bonmassar E, Jiricny J, D'Atri S.
    Mol Pharmacol; 2004 Sep 01; 66(3):478-91. PubMed ID: 15322239
    [Abstract] [Full Text] [Related]

  • 18. Radiosensitization by Chir-124, a selective CHK1 inhibitor: effects of p53 and cell cycle checkpoints.
    Tao Y, Leteur C, Yang C, Zhang P, Castedo M, Pierré A, Golsteyn RM, Bourhis J, Kroemer G, Deutsch E.
    Cell Cycle; 2009 Apr 15; 8(8):1196-205. PubMed ID: 19305158
    [Abstract] [Full Text] [Related]

  • 19. Ataxia telangiectasia-mutated-Rad3-related DNA damage checkpoint signaling pathway triggered by hepatitis B virus infection.
    Zhao F, Hou NB, Yang XL, He X, Liu Y, Zhang YH, Wei CW, Song T, Li L, Ma QJ, Zhong H.
    World J Gastroenterol; 2008 Oct 28; 14(40):6163-70. PubMed ID: 18985806
    [Abstract] [Full Text] [Related]

  • 20. Depletion of ATR selectively sensitizes ATM-deficient human mammary epithelial cells to ionizing radiation and DNA-damaging agents.
    Cui Y, Palii SS, Innes CL, Paules RS.
    Cell Cycle; 2014 Oct 28; 13(22):3541-50. PubMed ID: 25483091
    [Abstract] [Full Text] [Related]

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