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Journal Abstract Search

86 related items for PubMed ID: 21567968

  • 1. Selective inhibition of iNOS by benzyl- and dibenzyl derivatives of N-(3-aminobenzyl)acetamidine.
    Fantacuzzi M, Maccallini C, Lannutti F, Patruno A, Masella S, Pesce M, Speranza L, Ammazzalorso A, De Filippis B, Giampietro L, Re N, Amoroso R.
    ChemMedChem; 2011 Jul 04; 6(7):1203-6. PubMed ID: 21567968
    [No Abstract] [Full Text] [Related]

  • 2. Synthesis, biological evaluation, and docking studies of N-substituted acetamidines as selective inhibitors of inducible nitric oxide synthase.
    Maccallini C, Patruno A, Besker N, Alì JI, Ammazzalorso A, De Filippis B, Franceschelli S, Giampietro L, Pesce M, Reale M, Tricca ML, Re N, Felaco M, Amoroso R.
    J Med Chem; 2009 Mar 12; 52(5):1481-5. PubMed ID: 19203270
    [Abstract] [Full Text] [Related]

  • 3. Selective inhibition of inducible nitric oxide synthase by derivatives of acetamidine.
    Maccallini C, Patruno A, Ammazzalorso A, De Filippis B, Fantacuzzi M, Franceschelli S, Giampietro L, Masella S, Tricca ML, Amoroso R.
    Med Chem; 2012 Nov 12; 8(6):991-5. PubMed ID: 22741778
    [Abstract] [Full Text] [Related]

  • 4. N-Phenylamidines as selective inhibitors of human neuronal nitric oxide synthase: structure-activity studies and demonstration of in vivo activity.
    Collins JL, Shearer BG, Oplinger JA, Lee S, Garvey EP, Salter M, Duffy C, Burnette TC, Furfine ES.
    J Med Chem; 1998 Jul 16; 41(15):2858-71. PubMed ID: 9667974
    [Abstract] [Full Text] [Related]

  • 5. Novel nanomolar imidazo[4,5-b]pyridines as selective nitric oxide synthase (iNOS) inhibitors: SAR and structural insights.
    Grädler U, Fuchss T, Ulrich WR, Boer R, Strub A, Hesslinger C, Anézo C, Diederichs K, Zaliani A.
    Bioorg Med Chem Lett; 2011 Jul 15; 21(14):4228-32. PubMed ID: 21684157
    [Abstract] [Full Text] [Related]

  • 6. Heteroalicyclic carboxamidines as inhibitors of inducible nitric oxide synthase; the identification of (2R)-2-pyrrolidinecarboxamidine as a potent and selective haem-co-ordinating inhibitor.
    Young RJ, Alderton W, Angell AD, Beswick PJ, Brown D, Chambers CL, Crowe MC, Dawson J, Hamlett CC, Hodgson ST, Kleanthous S, Knowles RG, Russell LJ, Stocker R, Woolven JM.
    Bioorg Med Chem Lett; 2011 May 15; 21(10):3037-40. PubMed ID: 21482467
    [Abstract] [Full Text] [Related]

  • 7. Differential effects of selective and non-selective inhibition of nitric oxide synthase on the expression and activity of cyclooxygenase-2 during gastric ulcer healing.
    Guo JS, Cho CH, Wang JY, Koo MW.
    Eur J Pharmacol; 2006 May 01; 536(3):301-8. PubMed ID: 16600210
    [Abstract] [Full Text] [Related]

  • 8. Suppression of acute experimental colitis by a highly selective inducible nitric-oxide synthase inhibitor, N-[3-(aminomethyl)benzyl]acetamidine.
    Kankuri E, Vaali K, Knowles RG, Lähde M, Korpela R, Vapaatalo H, Moilanen E.
    J Pharmacol Exp Ther; 2001 Sep 01; 298(3):1128-32. PubMed ID: 11504810
    [Abstract] [Full Text] [Related]

  • 9. The discovery of novel, potent and highly selective inhibitors of inducible nitric oxide synthase (iNOS).
    Cheshire DR, Åberg A, Andersson GM, Andrews G, Beaton HG, Birkinshaw TN, Boughton-Smith N, Connolly S, Cook TR, Cooper A, Cooper SL, Cox D, Dixon J, Gensmantel N, Hamley PJ, Harrison R, Hartopp P, Käck H, Leeson PD, Luker T, Mete A, Millichip I, Nicholls DJ, Pimm AD, St-Gallay SA, Wallace AV.
    Bioorg Med Chem Lett; 2011 Apr 15; 21(8):2468-71. PubMed ID: 21398123
    [Abstract] [Full Text] [Related]

  • 10. Mechanism of inactivation of inducible nitric oxide synthase by amidines. Irreversible enzyme inactivation without inactivator modification.
    Zhu Y, Nikolic D, Van Breemen RB, Silverman RB.
    J Am Chem Soc; 2005 Jan 26; 127(3):858-68. PubMed ID: 15656623
    [Abstract] [Full Text] [Related]

  • 11. Phenylpyrrole derivatives as neural and inducible nitric oxide synthase (nNOS and iNOS) inhibitors.
    López Cara LC, Camacho ME, Carrión MD, Tapias V, Gallo MA, Escames G, Acuña-Castroviejo D, Espinosa A, Entrena A.
    Eur J Med Chem; 2009 Jun 26; 44(6):2655-66. PubMed ID: 19117642
    [Abstract] [Full Text] [Related]

  • 12. Synthesis, bioevaluation and docking studies of new imidamide derivatives as nitric oxide synthase inhibitors.
    Arias F, Franco-Montalban F, Romero M, Carrión MD, Camacho ME.
    Bioorg Med Chem; 2021 Aug 15; 44():116294. PubMed ID: 34218000
    [Abstract] [Full Text] [Related]

  • 13. Discovery of a series of aminopiperidines as novel iNOS inhibitors.
    Le Bourdonnec B, Leister LK, Ajello CA, Cassel JA, Seida PR, O'Hare H, Gu M, Chu GH, Tuthill PA, DeHaven RN, Dolle RE.
    Bioorg Med Chem Lett; 2008 Jan 01; 18(1):336-43. PubMed ID: 18024030
    [Abstract] [Full Text] [Related]

  • 14. Selective inhibition of inducible nitric oxide synthase reduces neurological deficit but not cerebral edema following traumatic brain injury.
    Louin G, Marchand-Verrecchia C, Palmier B, Plotkine M, Jafarian-Tehrani M.
    Neuropharmacology; 2006 Feb 01; 50(2):182-90. PubMed ID: 16242164
    [Abstract] [Full Text] [Related]

  • 15. Pyrazoles and pyrazolines as neural and inducible nitric oxide synthase (nNOS and iNOS) potential inhibitors (III).
    Carrión MD, López Cara LC, Camacho ME, Tapias V, Escames G, Acuña-Castroviejo D, Espinosa A, Gallo MA, Entrena A.
    Eur J Med Chem; 2008 Nov 01; 43(11):2579-91. PubMed ID: 18325637
    [Abstract] [Full Text] [Related]

  • 16. Hindlimb ischemia/reperfusion-induced remote injury to the small intestine: role of inducible nitric-oxide synthase-derived nitric oxide.
    Katada K, Bihari A, Badhwar A, Yoshida N, Yoshikawa T, Potter RF, Cepinskas G.
    J Pharmacol Exp Ther; 2009 Jun 01; 329(3):919-27. PubMed ID: 19270191
    [Abstract] [Full Text] [Related]

  • 17. Inhibition of nitric oxide synthase reduces renal ischemia/reperfusion injury.
    Mark LA, Robinson AV, Schulak JA.
    J Surg Res; 2005 Dec 01; 129(2):236-41. PubMed ID: 16140334
    [Abstract] [Full Text] [Related]

  • 18. Structure-activity relationship of novel and known inhibitors of human dimethylarginine dimethylaminohydrolase-1: alkenyl-amidines as new leads.
    Kotthaus J, Schade D, Muschick N, Beitz E, Clement B.
    Bioorg Med Chem; 2008 Dec 15; 16(24):10205-9. PubMed ID: 19013076
    [Abstract] [Full Text] [Related]

  • 19. Heteroaromatic-aminomethyl quinolones: potent and selective iNOS inhibitors.
    Durón SG, Lindstrom A, Bonnefous C, Zhang H, Chen X, Symons KT, Sablad M, Rozenkrants N, Zhang Y, Wang L, Yazdani N, Shiau AK, Noble SA, Rix P, Rao TS, Hassig CA, Smith ND.
    Bioorg Med Chem Lett; 2012 Jan 15; 22(2):1237-41. PubMed ID: 22182498
    [Abstract] [Full Text] [Related]

  • 20. The novel imidazopyridine 2-[2-(4-methoxy-pyridin-2-yl)-ethyl]-3H-imidazo[4,5-b]pyridine (BYK191023) is a highly selective inhibitor of the inducible nitric-oxide synthase.
    Strub A, Ulrich WR, Hesslinger C, Eltze M, Fuchss T, Strassner J, Strand S, Lehner MD, Boer R.
    Mol Pharmacol; 2006 Jan 15; 69(1):328-37. PubMed ID: 16223957
    [Abstract] [Full Text] [Related]

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