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Journal Abstract Search

174 related items for PubMed ID: 21568876

  • 1. Design, synthesis of novel quinazolone alkaloids derivatives as potential antitumor agents.
    Zheng Y, Sun M, Liu Y, Li M, Ji M.
    Med Chem; 2011 Jul; 7(4):295-300. PubMed ID: 21568876
    [Abstract] [Full Text] [Related]

  • 2. Design and synthesis of a quinazolinone natural product-templated library with cytotoxic activity.
    Liu JF, Kaselj M, Isome Y, Ye P, Sargent K, Sprague K, Cherrak D, Wilson CJ, Si Y, Yohannes D, Ng SC.
    J Comb Chem; 2006 Jul; 8(1):7-10. PubMed ID: 16398546
    [No Abstract] [Full Text] [Related]

  • 3. Development of a series of novel 4-anlinoquinazoline derivatives possessing quinazoline skeleton: Design, synthesis, EGFR kinase inhibitory efficacy, and evaluation of anticancer activities in vitro.
    Chang J, Ren H, Zhao M, Chong Y, Zhao W, He Y, Zhao Y, Zhang H, Qi C.
    Eur J Med Chem; 2017 Sep 29; 138():669-688. PubMed ID: 28711702
    [Abstract] [Full Text] [Related]

  • 4. Design, synthesis and assessment of new series of quinazolinone derivatives as EGFR inhibitors along with their cytotoxic evaluation against MCF7 and A549 cancer cell lines.
    Aziz MW, Kamal AM, Mohamed KO, Elgendy AA.
    Bioorg Med Chem Lett; 2021 Jun 01; 41():127987. PubMed ID: 33771586
    [Abstract] [Full Text] [Related]

  • 5. Design, synthesis, and biological evaluation of novel 3-substituted imidazo[1,2-a]pyridine and quinazolin-4(3H)-one derivatives as PI3Kα inhibitors.
    Fan YH, Li W, Liu DD, Bai MX, Song HR, Xu YN, Lee S, Zhou ZP, Wang J, Ding HW.
    Eur J Med Chem; 2017 Oct 20; 139():95-106. PubMed ID: 28800461
    [Abstract] [Full Text] [Related]

  • 6. Design, synthesis and in vitro biological evaluation of quinazolinone derivatives as EGFR inhibitors for antitumor treatment.
    Le Y, Gan Y, Fu Y, Liu J, Li W, Zou X, Zhou Z, Wang Z, Ouyang G, Yan L.
    J Enzyme Inhib Med Chem; 2020 Dec 20; 35(1):555-564. PubMed ID: 31967481
    [Abstract] [Full Text] [Related]

  • 7. Design, synthesis and biological evaluation of novel 4-anlinoquinazoline derivatives as EGFR inhibitors with the potential to inhibit the gefitinib-resistant nonsmall cell lung cancers.
    Wang C, Xu S, Peng L, Zhang B, Zhang H, Hu Y, Zheng P, Zhu W.
    J Enzyme Inhib Med Chem; 2019 Dec 20; 34(1):203-217. PubMed ID: 30835140
    [Abstract] [Full Text] [Related]

  • 8. Design, synthesis and biological evaluation of some novel quinazolinone derivatives as potent apoptotic inducers.
    Nowar RM, A Osman EE, Abou-Seri SM, El Moghazy SM, Abou El Ella DA.
    Future Med Chem; 2018 May 01; 10(10):1191-1205. PubMed ID: 29749767
    [Abstract] [Full Text] [Related]

  • 9. Design, synthesis, and anti-proliferative evaluation of new quinazolin-4(3H)-ones as potential VEGFR-2 inhibitors.
    El-Adl K, El-Helby AA, Ayyad RR, Mahdy HA, Khalifa MM, Elnagar HA, Mehany ABM, Metwaly AM, Elhendawy MA, Radwan MM, ElSohly MA, Eissa IH.
    Bioorg Med Chem; 2021 Jan 01; 29():115872. PubMed ID: 33214036
    [Abstract] [Full Text] [Related]

  • 10. Synthesis, antitumor activity and molecular docking study of some novel 3-benzyl-4(3H)quinazolinone analogues.
    Al-Suwaidan IA, Abdel-Aziz AA, Shawer TZ, Ayyad RR, Alanazi AM, El-Morsy AM, Mohamed MA, Abdel-Aziz NI, El-Sayed MA, El-Azab AS.
    J Enzyme Inhib Med Chem; 2016 Jan 01; 31(1):78-89. PubMed ID: 25815668
    [Abstract] [Full Text] [Related]

  • 11. Design and synthesis of 1,4-substituted 1H-1,2,3-triazolo-quinazolin-4(3H)-ones by Huisgen 1,3-dipolar cycloaddition with PI3Kγ isoform selective activity.
    Srinivas M, Singh Pathania A, Mahajan P, Verma PK, Chobe SS, Malik FA, Nargotra A, Vishwakarma RA, Sawant SD.
    Bioorg Med Chem Lett; 2018 Apr 01; 28(6):1005-1010. PubMed ID: 29486969
    [Abstract] [Full Text] [Related]

  • 12. Synthesis and cytotoxicity testing of novel 2-(3-substituted-6-chloro-1,1-dioxo-1,4,2-benzodithiazin-7-yl)-3-phenyl-4(3H)-quinazolinones.
    Pomarnacka E, Maruszak M, Langowska K, Reszka P, Bednarski PJ.
    Arch Pharm (Weinheim); 2008 Aug 01; 341(8):485-90. PubMed ID: 18618486
    [Abstract] [Full Text] [Related]

  • 13. Design, synthesis and evaluation of alkylphosphocholine-gefitinib conjugates as multitarget anticancer agents.
    Alam MM, Hassan AHE, Kwon YH, Lee HJ, Kim NY, Min KH, Lee SY, Kim DH, Lee YS.
    Arch Pharm Res; 2018 Jan 01; 41(1):35-45. PubMed ID: 29094267
    [Abstract] [Full Text] [Related]

  • 14. Synthesis, Molecular Modeling and Biological Evaluation of 4-Alkoxyquinazoline Derivatives as Novel Inhibitors of VEGFR2.
    Lu L, Zhao TT, Liu TB, Sun WX, Xu C, Li DD, Zhu HL.
    Chem Pharm Bull (Tokyo); 2016 Nov 01; 64(11):1570-1575. PubMed ID: 27568484
    [Abstract] [Full Text] [Related]

  • 15. Design, Synthesis, and Antitumor Activity of Novel Quinazoline Derivatives.
    Wang L, Li P, Li B, Wang Y, Li J, Song L.
    Molecules; 2017 Sep 28; 22(10):. PubMed ID: 28956845
    [Abstract] [Full Text] [Related]

  • 16. Parallel solution phase synthesis of 3,6,7-4(3H)-quinazolinones and evaluation of their antitumor activities against human cancer.
    Wu H, Xie X, Liu G.
    J Comb Chem; 2010 May 10; 12(3):346-55. PubMed ID: 20196566
    [Abstract] [Full Text] [Related]

  • 17. Synthesis and antitumor evaluation of trimethoxyanilides based on 4(3H)-quinazolinone scaffolds.
    Mohamed MA, Ayyad RR, Shawer TZ, Abdel-Aziz AA, El-Azab AS.
    Eur J Med Chem; 2016 Apr 13; 112():106-113. PubMed ID: 26890117
    [Abstract] [Full Text] [Related]

  • 18. Design, synthesis, anti-tumor activity, and molecular modeling of quinazoline and pyrido[2,3-d]pyrimidine derivatives targeting epidermal growth factor receptor.
    Hou J, Wan S, Wang G, Zhang T, Li Z, Tian Y, Yu Y, Wu X, Zhang J.
    Eur J Med Chem; 2016 Aug 08; 118():276-89. PubMed ID: 27132165
    [Abstract] [Full Text] [Related]

  • 19. Synthesis, in vitro antitumour activity, and molecular docking study of novel 2-substituted mercapto-3-(3,4,5-trimethoxybenzyl)-4(3H)-quinazolinone analogues.
    El-Azab AS, Abdel-Aziz AA, Ghabbour HA, Al-Gendy MA.
    J Enzyme Inhib Med Chem; 2017 Dec 08; 32(1):1229-1239. PubMed ID: 28948843
    [Abstract] [Full Text] [Related]

  • 20. Design, Synthesis, and Evaluation of New Selective NM23-H2 Binders as c-MYC Transcription Inhibitors via Disruption of the NM23-H2/G-Quadruplex Interaction.
    Wang YQ, Huang ZL, Chen SB, Wang CX, Shan C, Yin QK, Ou TM, Li D, Gu LQ, Tan JH, Huang ZS.
    J Med Chem; 2017 Aug 24; 60(16):6924-6941. PubMed ID: 28714689
    [Abstract] [Full Text] [Related]

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