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Journal Abstract Search

137 related items for PubMed ID: 21568887

  • 21. A glucose-based molecular rotor inhibitor of glycogen phosphorylase as a probe of cellular enzymatic function.
    Minadakis MP, Mavreas KF, Neofytos DD, Paschou M, Kogkaki A, Athanasiou V, Mamais M, Veclani D, Iatrou H, Venturini A, Chrysina ED, Papazafiri P, Gimisis T.
    Org Biomol Chem; 2022 Mar 23; 20(12):2407-2423. PubMed ID: 35119451
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  • 22. van der Waals interactions govern C-β-d-glucopyranosyl triazoles' nM inhibitory potency in human liver glycogen phosphorylase.
    Kantsadi AL, Stravodimos GA, Kyriakis E, Chatzileontiadou DSM, Solovou TGA, Kun S, Bokor É, Somsák L, Leonidas DD.
    J Struct Biol; 2017 Jul 23; 199(1):57-67. PubMed ID: 28483603
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  • 23. Identification, synthesis, and characterization of new glycogen phosphorylase inhibitors binding to the allosteric AMP site.
    Kristiansen M, Andersen B, Iversen LF, Westergaard N.
    J Med Chem; 2004 Jul 01; 47(14):3537-45. PubMed ID: 15214781
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  • 24. Physiological control of liver glycogen metabolism: lessons from novel glycogen phosphorylase inhibitors.
    Agius L.
    Mini Rev Med Chem; 2010 Oct 01; 10(12):1175-87. PubMed ID: 20716056
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  • 25. Glycogen phosphorylase inhibitors: a patent review (2008 - 2012).
    Gaboriaud-Kolar N, Skaltsounis AL.
    Expert Opin Ther Pat; 2013 Aug 01; 23(8):1017-32. PubMed ID: 23627914
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  • 26. Modeling aided design of potent glycogen phosphorylase inhibitors.
    Deng Q, Lu Z, Bohn J, Ellsworth KP, Myers RW, Geissler WM, Harris G, Willoughby CA, Chapman K, McKeever B, Mosley R.
    J Mol Graph Model; 2005 Apr 01; 23(5):457-64. PubMed ID: 15781188
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  • 27. Synthetic, enzyme kinetic, and protein crystallographic studies of C-β-d-glucopyranosyl pyrroles and imidazoles reveal and explain low nanomolar inhibition of human liver glycogen phosphorylase.
    Kantsadi AL, Bokor É, Kun S, Stravodimos GA, Chatzileontiadou DSM, Leonidas DD, Juhász-Tóth É, Szakács A, Batta G, Docsa T, Gergely P, Somsák L.
    Eur J Med Chem; 2016 Nov 10; 123():737-745. PubMed ID: 27522507
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  • 28. Crystallographic and computational studies on 4-phenyl-N-(beta-D-glucopyranosyl)-1H-1,2,3-triazole-1-acetamide, an inhibitor of glycogen phosphorylase: comparison with alpha-D-glucose, N-acetyl-beta-D-glucopyranosylamine and N-benzoyl-N'-beta-D-glucopyranosyl urea binding.
    Alexacou KM, Hayes JM, Tiraidis C, Zographos SE, Leonidas DD, Chrysina ED, Archontis G, Oikonomakos NG, Paul JV, Varghese B, Loganathan D.
    Proteins; 2008 May 15; 71(3):1307-23. PubMed ID: 18041758
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  • 30. The 1.76 A resolution crystal structure of glycogen phosphorylase B complexed with glucose, and CP320626, a potential antidiabetic drug.
    Oikonomakos NG, Zographos SE, Skamnaki VT, Archontis G.
    Bioorg Med Chem; 2002 May 15; 10(5):1313-9. PubMed ID: 11886794
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  • 31. Allosteric inhibition of glycogen phosphorylase a by the potential antidiabetic drug 3-isopropyl 4-(2-chlorophenyl)-1,4-dihydro-1-ethyl-2-methyl-pyridine-3,5,6-tricarbo xylate.
    Oikonomakos NG, Tsitsanou KE, Zographos SE, Skamnaki VT, Goldmann S, Bischoff H.
    Protein Sci; 1999 Oct 15; 8(10):1930-45. PubMed ID: 10548038
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  • 32. The σ-hole phenomenon of halogen atoms forms the structural basis of the strong inhibitory potency of C5 halogen substituted glucopyranosyl nucleosides towards glycogen phosphorylase b.
    Kantsadi AL, Hayes JM, Manta S, Skamnaki VT, Kiritsis C, Psarra AM, Koutsogiannis Z, Dimopoulou A, Theofanous S, Nikoleousakos N, Zoumpoulakis P, Kontou M, Papadopoulos G, Zographos SE, Komiotis D, Leonidas DD.
    ChemMedChem; 2012 Apr 15; 7(4):722-32. PubMed ID: 22267166
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  • 36. N-(4-Substituted-benzoyl)-N'-(β-d-glucopyranosyl)ureas as inhibitors of glycogen phosphorylase: Synthesis and evaluation by kinetic, crystallographic, and molecular modelling methods.
    Nagy V, Felföldi N, Kónya B, Praly JP, Docsa T, Gergely P, Chrysina ED, Tiraidis C, Kosmopoulou MN, Alexacou KM, Konstantakaki M, Leonidas DD, Zographos SE, Oikonomakos NG, Kozmon S, Tvaroška I, Somsák L.
    Bioorg Med Chem; 2012 Mar 01; 20(5):1801-16. PubMed ID: 22325154
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  • 37. Novel thienopyrrole glycogen phosphorylase inhibitors: synthesis, in vitro SAR and crystallographic studies.
    Whittamore PR, Addie MS, Bennett SN, Birch AM, Butters M, Godfrey L, Kenny PW, Morley AD, Murray PM, Oikonomakos NG, Otterbein LR, Pannifer AD, Parker JS, Readman K, Siedlecki PS, Schofield P, Stocker A, Taylor MJ, Townsend LA, Whalley DP, Whitehouse J.
    Bioorg Med Chem Lett; 2006 Nov 01; 16(21):5567-71. PubMed ID: 16945526
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  • 38. Activation of human liver glycogen phosphorylase by alteration of the secondary structure and packing of the catalytic core.
    Rath VL, Ammirati M, LeMotte PK, Fennell KF, Mansour MN, Danley DE, Hynes TR, Schulte GK, Wasilko DJ, Pandit J.
    Mol Cell; 2000 Jul 01; 6(1):139-48. PubMed ID: 10949035
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  • 39. Evaluation of designed ligands by a multiple screening method: application to glycogen phosphorylase inhibitors constructed with a variety of approaches.
    So SS, Karplus M.
    J Comput Aided Mol Des; 2001 Jul 01; 15(7):613-47. PubMed ID: 11688944
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  • 40. Kinetic and crystallographic studies of glucopyranose spirohydantoin and glucopyranosylamine analogs inhibitors of glycogen phosphorylase.
    Watson KA, Chrysina ED, Tsitsanou KE, Zographos SE, Archontis G, Fleet GW, Oikonomakos NG.
    Proteins; 2005 Dec 01; 61(4):966-83. PubMed ID: 16222658
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