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378 related items for PubMed ID: 21586645
1. Requirement of replication checkpoint protein kinases Mec1/Rad53 for postreplication repair in yeast. Gangavarapu V, Santa Maria SR, Prakash S, Prakash L. mBio; 2011; 2(3):e00079-11. PubMed ID: 21586645 [Abstract] [Full Text] [Related]
2. Role of DNA damage-induced replication checkpoint in promoting lesion bypass by translesion synthesis in yeast. Pagès V, Santa Maria SR, Prakash L, Prakash S. Genes Dev; 2009 Jun 15; 23(12):1438-49. PubMed ID: 19528320 [Abstract] [Full Text] [Related]
3. Colocalization of Mec1 and Mrc1 is sufficient for Rad53 phosphorylation in vivo. Berens TJ, Toczyski DP. Mol Biol Cell; 2012 Mar 15; 23(6):1058-67. PubMed ID: 22298423 [Abstract] [Full Text] [Related]
4. Replisome instability, fork collapse, and gross chromosomal rearrangements arise synergistically from Mec1 kinase and RecQ helicase mutations. Cobb JA, Schleker T, Rojas V, Bjergbaek L, Tercero JA, Gasser SM. Genes Dev; 2005 Dec 15; 19(24):3055-69. PubMed ID: 16357221 [Abstract] [Full Text] [Related]
5. Rad53 regulates replication fork restart after DNA damage in Saccharomyces cerevisiae. Szyjka SJ, Aparicio JG, Viggiani CJ, Knott S, Xu W, Tavaré S, Aparicio OM. Genes Dev; 2008 Jul 15; 22(14):1906-20. PubMed ID: 18628397 [Abstract] [Full Text] [Related]
6. Separate roles for the DNA damage checkpoint protein kinases in stabilizing DNA replication forks. Segurado M, Diffley JF. Genes Dev; 2008 Jul 01; 22(13):1816-27. PubMed ID: 18593882 [Abstract] [Full Text] [Related]
7. Reconstitution of Rad53 activation by Mec1 through adaptor protein Mrc1. Chen SH, Zhou H. J Biol Chem; 2009 Jul 10; 284(28):18593-604. PubMed ID: 19457865 [Abstract] [Full Text] [Related]
8. Mrc1 is a replication fork component whose phosphorylation in response to DNA replication stress activates Rad53. Osborn AJ, Elledge SJ. Genes Dev; 2003 Jul 15; 17(14):1755-67. PubMed ID: 12865299 [Abstract] [Full Text] [Related]
9. Genetic Evidence for Roles of Yeast Mitotic Cyclins at Single-Stranded Gaps Created by DNA Replication. Signon L. G3 (Bethesda); 2018 Feb 02; 8(2):737-752. PubMed ID: 29279302 [Abstract] [Full Text] [Related]
10. Analysis of the tolerance to DNA alkylating damage in MEC1 and RAD53 checkpoint mutants of Saccharomyces cerevisiae. Gallego-Sánchez A, Ufano S, Andrés S, Bueno A. PLoS One; 2013 Feb 02; 8(11):e81108. PubMed ID: 24260543 [Abstract] [Full Text] [Related]
11. Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint. Tercero JA, Diffley JF. Nature; 2001 Aug 02; 412(6846):553-7. PubMed ID: 11484057 [Abstract] [Full Text] [Related]
12. Signaling pathways of replication stress in yeast. Pardo B, Crabbé L, Pasero P. FEMS Yeast Res; 2017 Mar 01; 17(2):. PubMed ID: 27915243 [Abstract] [Full Text] [Related]
13. Mrc1 phosphorylation in response to DNA replication stress is required for Mec1 accumulation at the stalled fork. Naylor ML, Li JM, Osborn AJ, Elledge SJ. Proc Natl Acad Sci U S A; 2009 Aug 04; 106(31):12765-70. PubMed ID: 19515819 [Abstract] [Full Text] [Related]
14. Mec1-independent activation of the Rad53 checkpoint kinase revealed by quantitative analysis of protein localization dynamics. Ho B, Sanford EJ, Loll-Krippleber R, Torres NP, Smolka MB, Brown GW. Elife; 2023 Jun 06; 12():. PubMed ID: 37278514 [Abstract] [Full Text] [Related]