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324 related items for PubMed ID: 21590445

  • 21. C677T and A1298C MTHFR polymorphisms, a challenge for antifolate and fluoropyrimidine-based therapy personalisation.
    De Mattia E, Toffoli G.
    Eur J Cancer; 2009 May; 45(8):1333-51. PubMed ID: 19144510
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  • 22. 677TT genotype is associated with elevated risk of methotrexate (MTX) toxicity in juvenile idiopathic arthritis: treatment outcome, erythrocyte concentrations of MTX and folates, and MTHFR polymorphisms.
    Tuková J, Chládek J, Hroch M, Nemcová D, Hoza J, Dolezalová P.
    J Rheumatol; 2010 Oct; 37(10):2180-6. PubMed ID: 20595278
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  • 23. MTHFR 677 (C-->T) polymorphism is not relevant for prognosis or therapy-associated toxicity in pediatric NHL: results from 484 patients of multicenter trial NHL-BFM 95.
    Seidemann K, Book M, Zimmermann M, Meyer U, Welte K, Stanulla M, Reiter A.
    Ann Hematol; 2006 May; 85(5):291-300. PubMed ID: 16463153
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  • 24. A systematic review and meta-analysis of MTHFR polymorphisms in methotrexate toxicity prediction in pediatric acute lymphoblastic leukemia.
    Lopez-Lopez E, Martin-Guerrero I, Ballesteros J, Garcia-Orad A.
    Pharmacogenomics J; 2013 Dec; 13(6):498-506. PubMed ID: 23089671
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  • 33. Genetic polymorphisms in candidate genes predict increased toxicity with methotrexate therapy in Lebanese children with acute lymphoblastic leukemia.
    Zgheib NK, Akra-Ismail M, Aridi C, Mahfouz R, Abboud MR, Solh H, Muwakkit SA.
    Pharmacogenet Genomics; 2014 Aug; 24(8):387-96. PubMed ID: 25007187
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  • 35. Methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms and therapy-related toxicity in children treated for acute lymphoblastic leukemia and non-Hodgkin lymphoma.
    Kantar M, Kosova B, Cetingul N, Gumus S, Toroslu E, Zafer N, Topcuoglu N, Aksoylar S, Cinar M, Tetik A, Eroglu Z.
    Leuk Lymphoma; 2009 Jun; 50(6):912-7. PubMed ID: 19391036
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  • 40. Methylenetetrahydrofolate reductase C677T polymorphism: association with risk for childhood acute lymphoblastic leukemia and response during the initial phase of chemotherapy in greek patients.
    Chatzidakis K, Goulas A, Athanassiadou-Piperopoulou F, Fidani L, Koliouskas D, Mirtsou V.
    Pediatr Blood Cancer; 2006 Aug; 47(2):147-51. PubMed ID: 16123993
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