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154 related items for PubMed ID: 21600917

  • 1. Thermal and chemical denaturation of the BRCT functional module of human 53BP1.
    Thanassoulas A, Nomikos M, Theodoridou M, Stavros P, Mastellos D, Nounesis G.
    Int J Biol Macromol; 2011 Oct 01; 49(3):297-304. PubMed ID: 21600917
    [Abstract] [Full Text] [Related]

  • 2. Comparison of BRCT domains of BRCA1 and 53BP1: a biophysical analysis.
    Ekblad CM, Friedler A, Veprintsev D, Weinberg RL, Itzhaki LS.
    Protein Sci; 2004 Mar 01; 13(3):617-25. PubMed ID: 14978302
    [Abstract] [Full Text] [Related]

  • 3. Thermal denaturation of the BRCT tandem repeat region of human tumour suppressor gene product BRCA1.
    Pyrpassopoulos S, Ladopoulou A, Vlassi M, Papanikolau Y, Vorgias CE, Yannoukakos D, Nounesis G.
    Biophys Chem; 2005 Apr 01; 114(1):1-12. PubMed ID: 15792855
    [Abstract] [Full Text] [Related]

  • 4. Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure.
    Joo WS, Jeffrey PD, Cantor SB, Finnin MS, Livingston DM, Pavletich NP.
    Genes Dev; 2002 Mar 01; 16(5):583-93. PubMed ID: 11877378
    [Abstract] [Full Text] [Related]

  • 5. Crystal structure of human 53BP1 BRCT domains bound to p53 tumour suppressor.
    Derbyshire DJ, Basu BP, Serpell LC, Joo WS, Date T, Iwabuchi K, Doherty AJ.
    EMBO J; 2002 Jul 15; 21(14):3863-72. PubMed ID: 12110597
    [Abstract] [Full Text] [Related]

  • 6. Thermodynamic study of the BRCT domain of BARD1 and its interaction with the -pSER-X-X-Phe- motif-containing BRIP1 peptide.
    Thanassoulas A, Nomikos M, Theodoridou M, Yannoukakos D, Mastellos D, Nounesis G.
    Biochim Biophys Acta; 2010 Sep 15; 1804(9):1908-16. PubMed ID: 20451671
    [Abstract] [Full Text] [Related]

  • 7. Thermal unfolding of human BRCA1 BRCT-domain variants.
    Nikolopoulos G, Pyrpassopoulos S, Thanassoulas A, Klimentzou P, Zikos C, Vlassi M, Vorgias CE, Yannoukakos D, Nounesis G.
    Biochim Biophys Acta; 2007 Jun 15; 1774(6):772-80. PubMed ID: 17493881
    [Abstract] [Full Text] [Related]

  • 8. Characterization of cancer-linked BRCA1-BRCT missense variants and their interaction with phosphoprotein targets.
    Drikos I, Nounesis G, Vorgias CE.
    Proteins; 2009 Nov 01; 77(2):464-76. PubMed ID: 19452558
    [Abstract] [Full Text] [Related]

  • 9. Crystal structure of the BARD1 BRCT domains.
    Birrane G, Varma AK, Soni A, Ladias JA.
    Biochemistry; 2007 Jul 03; 46(26):7706-12. PubMed ID: 17550235
    [Abstract] [Full Text] [Related]

  • 10. "Similarity trap" in protein-protein interactions could be carcinogenic: simulations of p53 core domain complexed with 53BP1 and BRCA1 BRCT domains.
    Liu J, Pan Y, Ma B, Nussinov R.
    Structure; 2006 Dec 03; 14(12):1811-21. PubMed ID: 17161371
    [Abstract] [Full Text] [Related]

  • 11. Multimodal approach to explore the pathogenicity of BARD1, ARG 658 CYS, and ILE 738 VAL mutants.
    Choudhary RK, Vikrant, Siddiqui QM, Thapa PS, Raikundalia S, Gadewal N, Kumar NS, Hosur MV, Varma AK.
    J Biomol Struct Dyn; 2016 Jul 03; 34(7):1533-44. PubMed ID: 26307947
    [Abstract] [Full Text] [Related]

  • 12. Structural requirements for the BARD1 tumor suppressor in chromosomal stability and homology-directed DNA repair.
    Laufer M, Nandula SV, Modi AP, Wang S, Jasin M, Murty VV, Ludwig T, Baer R.
    J Biol Chem; 2007 Nov 23; 282(47):34325-33. PubMed ID: 17848578
    [Abstract] [Full Text] [Related]

  • 13. The BARD1 C-terminal domain structure and interactions with polyadenylation factor CstF-50.
    Edwards RA, Lee MS, Tsutakawa SE, Williams RS, Nazeer I, Kleiman FE, Tainer JA, Glover JN.
    Biochemistry; 2008 Nov 04; 47(44):11446-56. PubMed ID: 18842000
    [Abstract] [Full Text] [Related]

  • 14. Structural basis to stabilize the domain motion of BARD1-ARD BRCT by CstF50.
    Choudhary RK, Siddiqui MQ, Thapa PS, Gadewal N, Nachimuthu SK, Varma AK.
    Sci Rep; 2017 Jun 20; 7(1):3849. PubMed ID: 28634376
    [Abstract] [Full Text] [Related]

  • 15. Interactions between BRCT repeats and phosphoproteins: tangled up in two.
    Glover JN, Williams RS, Lee MS.
    Trends Biochem Sci; 2004 Nov 20; 29(11):579-85. PubMed ID: 15501676
    [Abstract] [Full Text] [Related]

  • 16. Primary structure-based function characterization of BRCT domain replicates in BRCA1.
    Chen Y, Borowicz S, Fackenthal J, Collart FR, Myatt E, Moy S, Babnigg G, Wilton R, Boernke WE, Schiffer M, Stevens FJ, Olopade OI.
    Biochem Biophys Res Commun; 2006 Jun 23; 345(1):188-96. PubMed ID: 16677609
    [Abstract] [Full Text] [Related]

  • 17. Structural consequences of a cancer-causing BRCA1-BRCT missense mutation.
    Williams RS, Glover JN.
    J Biol Chem; 2003 Jan 24; 278(4):2630-5. PubMed ID: 12427738
    [Abstract] [Full Text] [Related]

  • 18. Solution structure, backbone dynamics, and association behavior of the C-terminal BRCT domain from the breast cancer-associated protein BRCA1.
    Gaiser OJ, Ball LJ, Schmieder P, Leitner D, Strauss H, Wahl M, Kühne R, Oschkinat H, Heinemann U.
    Biochemistry; 2004 Dec 28; 43(51):15983-95. PubMed ID: 15609993
    [Abstract] [Full Text] [Related]

  • 19. A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins.
    Bork P, Hofmann K, Bucher P, Neuwald AF, Altschul SF, Koonin EV.
    FASEB J; 1997 Jan 28; 11(1):68-76. PubMed ID: 9034168
    [Abstract] [Full Text] [Related]

  • 20. Characterisation of the BRCT domains of the breast cancer susceptibility gene product BRCA1.
    Ekblad CM, Wilkinson HR, Schymkowitz JW, Rousseau F, Freund SM, Itzhaki LS.
    J Mol Biol; 2002 Jul 12; 320(3):431-42. PubMed ID: 12096901
    [Abstract] [Full Text] [Related]

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