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Journal Abstract Search

217 related items for PubMed ID: 2161228

  • 1. Enzyme interactions of 2,10-ethanoandrostene-3,17-dione: aromatase and 17 beta-hydroxysteroid dehydrogenase.
    Greway AT, Mentzer M, Levy MA.
    Biochem Int; 1990; 20(3):591-7. PubMed ID: 2161228
    [Abstract] [Full Text] [Related]

  • 2. Substituted C19 steroid analogs as inhibitors of aromatase.
    Brueggemeier RW, Snider CE, Counsell RE.
    Cancer Res; 1982 Aug; 42(8 Suppl):3334s-3337s. PubMed ID: 7083196
    [Abstract] [Full Text] [Related]

  • 3. Gas chromatography-mass spectrometric study of 19-oxygenation of the aromatase inhibitor 19-methylandrostenedione with human placental microsomes.
    Numazawa M, Nagaoka M, Handa W, Yamada A.
    Biol Pharm Bull; 2006 Jun; 29(6):1242-5. PubMed ID: 16755025
    [Abstract] [Full Text] [Related]

  • 4. Androst-5-ene-7,17-dione: a novel class of suicide substrate of aromatase.
    Numazawa M, Mutsumi A, Hoshi K, Tanaka Y.
    Biochem Biophys Res Commun; 1992 Jul 15; 186(1):32-9. PubMed ID: 1632774
    [Abstract] [Full Text] [Related]

  • 5. A new hypothesis based on suicide substrate inhibitor studies for the mechanism of action of aromatase.
    Covey DF, Hood WF.
    Cancer Res; 1982 Aug 15; 42(8 Suppl):3327s-3333s. PubMed ID: 7083195
    [Abstract] [Full Text] [Related]

  • 6. Accumulation of intermediates and isotopically sensitive enolization distinguish between aromatase (cytochrome P450 CYP19) from rat ovary and human placenta.
    Swinney DC, Watson DM, So OY.
    Arch Biochem Biophys; 1993 Aug 15; 305(1):61-7. PubMed ID: 8342956
    [Abstract] [Full Text] [Related]

  • 7. Aromatase inhibitors: effect of ring A and ring B unsaturation on aromatase inhibition by 4-thiosubstituted derivatives of 4-androstene-3,17-dione.
    Abul-Hajj YJ, Liu XP, Hedge M.
    Steroids; 1995 May 15; 60(5):423-7. PubMed ID: 7570717
    [Abstract] [Full Text] [Related]

  • 8. Aromatase-inhibitors of the androstenedione-type activate the 17 beta-hydroxysteroid-dehydrogenase in the rat testis tissue suspension model.
    Schröder H, Ziegler M, el Etreby MF.
    J Steroid Biochem; 1988 Oct 15; 31(4B):685-90. PubMed ID: 3199812
    [Abstract] [Full Text] [Related]

  • 9. Effect of ketoconazole on placental aromatase, 3 beta-hydroxysteroid dehydrogenase-isomerase and 17 beta-hydroxysteroid dehydrogenase.
    Ayub M, Stitch SR.
    J Steroid Biochem; 1986 Dec 15; 25(6):981-4. PubMed ID: 3025521
    [Abstract] [Full Text] [Related]

  • 10. Mechanism for aromatase inactivation by a suicide substrate, androst-4-ene-3,6,17-trione. The 4 beta, 5 beta-epoxy-19-oxo derivative as a reactive electrophile irreversibly binding to the active site.
    Numazawa M, Mutsumi A, Tachibana M.
    Biochem Pharmacol; 1996 Oct 25; 52(8):1253-9. PubMed ID: 8937433
    [Abstract] [Full Text] [Related]

  • 11. Time-dependent inactivation of aromatase by 6-alkylandrosta-1,4-diene-3,17-diones. Effects of length and configuration of 6-alkyl group.
    Numazawa M, Oshibe M, Yamaguchi S, Tachibana M.
    J Med Chem; 1996 Mar 01; 39(5):1033-8. PubMed ID: 8676338
    [Abstract] [Full Text] [Related]

  • 12. Stereochemistry of the functional group determines the mechanism of aromatase inhibition by 6-bromoandrostenedione.
    Osawa Y, Osawa Y, Coon MJ.
    Endocrinology; 1987 Sep 01; 121(3):1010-6. PubMed ID: 3622372
    [Abstract] [Full Text] [Related]

  • 13. Time-dependent aromatase inactivation by 4 beta,5 beta-epoxides of the natural substrate androstenedione and its 19-oxygenated analogs.
    Numazawa M, Yoshimura A, Tachibana M, Shelangouski M, Ishikawa M.
    Steroids; 2002 Mar 01; 67(3-4):185-93. PubMed ID: 11856542
    [Abstract] [Full Text] [Related]

  • 14. An efficient steroid pharmacophore-based strategy to identify new aromatase inhibitors.
    Neves MA, Dinis TC, Colombo G, Sá e Melo ML.
    Eur J Med Chem; 2009 Oct 01; 44(10):4121-7. PubMed ID: 19500885
    [Abstract] [Full Text] [Related]

  • 15. The effect of epitestosterone on estrogen biosynthesis in vitro.
    Bicíková M, Klak J, Hill M, Stárka L.
    Horm Metab Res; 2000 Apr 01; 32(4):125-8. PubMed ID: 10824706
    [Abstract] [Full Text] [Related]

  • 16. Enzyme inactivation by potential metabolites of an aromatase-activated inhibitor (MDL 18,962).
    Johnston JO, Wright CL, Holbert GW, Benson HD.
    J Enzyme Inhib; 1990 Apr 01; 4(2):137-42. PubMed ID: 2098520
    [Abstract] [Full Text] [Related]

  • 17. Synthesis of 2,2-dimethyl-4-hydroxy-4-androstene-3,17-dione as an inhibitor of aromatase.
    Furth PS, Rosenberger J, Marcotte PA, Robinson CH.
    J Enzyme Inhib; 1990 Apr 01; 4(2):131-5. PubMed ID: 2098519
    [Abstract] [Full Text] [Related]

  • 18. Tritium release from [19-3H]-19,19-difluoroandrost-4-ene-3,17-dione during inactivation of aromatase.
    Furth PS, Robinson CH.
    Biochemistry; 1989 Feb 07; 28(3):1254-9. PubMed ID: 2653438
    [Abstract] [Full Text] [Related]

  • 19. 6beta,19-Bridged androstenedione analogs as aromatase inhibitors.
    Komatsu S, Yaguchi A, Yamashita K, Nagaoka M, Numazawa M.
    Steroids; 2009 Nov 07; 74(12):884-9. PubMed ID: 19524602
    [Abstract] [Full Text] [Related]

  • 20. Biological characterization of A-ring steroids.
    Johnston JO, Wright CL, Burkhart JP, Peet NP.
    J Steroid Biochem Mol Biol; 1993 Mar 07; 44(4-6):623-31. PubMed ID: 8476773
    [Abstract] [Full Text] [Related]

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