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639 related items for PubMed ID: 21617228

  • 1. Phenethyl isothiocyanate (PEITC) promotes G2/M phase arrest via p53 expression and induces apoptosis through caspase- and mitochondria-dependent signaling pathways in human prostate cancer DU 145 cells.
    Tang NY, Huang YT, Yu CS, Ko YC, Wu SH, Ji BC, Yang JS, Yang JL, Hsia TC, Chen YY, Chung JG.
    Anticancer Res; 2011 May; 31(5):1691-702. PubMed ID: 21617228
    [Abstract] [Full Text] [Related]

  • 2. Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC)-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of caspase-3, mitochondria dysfunction and nitric oxide (NO) in human osteogenic sarcoma U-2 OS cells.
    Wu CL, Huang AC, Yang JS, Liao CL, Lu HF, Chou ST, Ma CY, Hsia TC, Ko YC, Chung JG.
    J Orthop Res; 2011 Aug; 29(8):1199-209. PubMed ID: 21374707
    [Abstract] [Full Text] [Related]

  • 3. Phenethyl isothiocyanate triggers apoptosis in human malignant melanoma A375.S2 cells through reactive oxygen species and the mitochondria-dependent pathways.
    Huang SH, Hsu MH, Hsu SC, Yang JS, Huang WW, Huang AC, Hsiao YP, Yu CC, Chung JG.
    Hum Exp Toxicol; 2014 Mar; 33(3):270-83. PubMed ID: 23760257
    [Abstract] [Full Text] [Related]

  • 4. The roles of AIF and Endo G in the apoptotic effects of benzyl isothiocyanate on DU 145 human prostate cancer cells via the mitochondrial signaling pathway.
    Liu KC, Huang YT, Wu PP, Ji BC, Yang JS, Yang JL, Chiu TH, Chueh FS, Chung JG.
    Int J Oncol; 2011 Mar; 38(3):787-96. PubMed ID: 21206973
    [Abstract] [Full Text] [Related]

  • 5. Phenethyl isothiocyanate induced apoptosis via down regulation of Bcl-2/XIAP and triggering of the mitochondrial pathway in MCF-7 cells.
    Lee JW, Cho MK.
    Arch Pharm Res; 2008 Dec; 31(12):1604-12. PubMed ID: 19099231
    [Abstract] [Full Text] [Related]

  • 6. Phenethyl isothiocyanate induces DNA damage-associated G2/M arrest and subsequent apoptosis in oral cancer cells with varying p53 mutations.
    Yeh YT, Yeh H, Su SH, Lin JS, Lee KJ, Shyu HW, Chen ZF, Huang SY, Su SJ.
    Free Radic Biol Med; 2014 Sep; 74():1-13. PubMed ID: 24952138
    [Abstract] [Full Text] [Related]

  • 7. Benzyl isothiocyanate (BITC) induces G2/M phase arrest and apoptosis in human melanoma A375.S2 cells through reactive oxygen species (ROS) and both mitochondria-dependent and death receptor-mediated multiple signaling pathways.
    Huang SH, Wu LW, Huang AC, Yu CC, Lien JC, Huang YP, Yang JS, Yang JH, Hsiao YP, Wood WG, Yu CS, Chung JG.
    J Agric Food Chem; 2012 Jan 18; 60(2):665-75. PubMed ID: 22148415
    [Abstract] [Full Text] [Related]

  • 8. Effects of antioxidants and caspase-3 inhibitor on the phenylethyl isothiocyanate-induced apoptotic signaling pathways in human PLC/PRF/5 cells.
    Wu SJ, Ng LT, Lin CC.
    Eur J Pharmacol; 2005 Aug 22; 518(2-3):96-106. PubMed ID: 16054126
    [Abstract] [Full Text] [Related]

  • 9. Caspase-dependent apoptosis induction by phenethyl isothiocyanate, a cruciferous vegetable-derived cancer chemopreventive agent, is mediated by Bak and Bax.
    Xiao D, Zeng Y, Choi S, Lew KL, Nelson JB, Singh SV.
    Clin Cancer Res; 2005 Apr 01; 11(7):2670-9. PubMed ID: 15814648
    [Abstract] [Full Text] [Related]

  • 10. Diallyl sulfide induces cell cycle arrest and apoptosis in HeLa human cervical cancer cells through the p53, caspase- and mitochondria-dependent pathways.
    Wu PP, Chung HW, Liu KC, Wu RS, Yang JS, Tang NY, Lo C, Hsia TC, Yu CC, Chueh FS, Lin SS, Chung JG.
    Int J Oncol; 2011 Jun 01; 38(6):1605-13. PubMed ID: 21424116
    [Abstract] [Full Text] [Related]

  • 11. Proteasome-mediated degradation of cell division cycle 25C and cyclin-dependent kinase 1 in phenethyl isothiocyanate-induced G2-M-phase cell cycle arrest in PC-3 human prostate cancer cells.
    Xiao D, Johnson CS, Trump DL, Singh SV.
    Mol Cancer Ther; 2004 May 01; 3(5):567-75. PubMed ID: 15141014
    [Abstract] [Full Text] [Related]

  • 12. Phenethyl isothiocyanate-induced apoptosis in PC-3 human prostate cancer cells is mediated by reactive oxygen species-dependent disruption of the mitochondrial membrane potential.
    Xiao D, Lew KL, Zeng Y, Xiao H, Marynowski SW, Dhir R, Singh SV.
    Carcinogenesis; 2006 Nov 01; 27(11):2223-34. PubMed ID: 16774948
    [Abstract] [Full Text] [Related]

  • 13. Ingestion of an isothiocyanate metabolite from cruciferous vegetables inhibits growth of human prostate cancer cell xenografts by apoptosis and cell cycle arrest.
    Chiao JW, Wu H, Ramaswamy G, Conaway CC, Chung FL, Wang L, Liu D.
    Carcinogenesis; 2004 Aug 01; 25(8):1403-8. PubMed ID: 15016658
    [Abstract] [Full Text] [Related]

  • 14. Danthron, an anthraquinone derivative, induces DNA damage and caspase cascades-mediated apoptosis in SNU-1 human gastric cancer cells through mitochondrial permeability transition pores and Bax-triggered pathways.
    Chiang JH, Yang JS, Ma CY, Yang MD, Huang HY, Hsia TC, Kuo HM, Wu PP, Lee TH, Chung JG.
    Chem Res Toxicol; 2011 Jan 14; 24(1):20-9. PubMed ID: 21126053
    [Abstract] [Full Text] [Related]

  • 15. Beta-phenylethyl isothiocyanate mediated apoptosis; contribution of Bax and the mitochondrial death pathway.
    Rose P, Armstrong JS, Chua YL, Ong CN, Whiteman M.
    Int J Biochem Cell Biol; 2005 Jan 14; 37(1):100-19. PubMed ID: 15381154
    [Abstract] [Full Text] [Related]

  • 16. A novel synthetic 2-(3-methoxyphenyl)-6,7-methylenedioxoquinolin-4-one arrests the G2/M phase arrest via Cdc25c and induces apoptosis through caspase- and mitochondria-dependent pathways in TSGH8301 human bladder cancer cells.
    Hsu SC, Yu CC, Yang JS, Lai KC, Wu SH, Lin JJ, Kuo JH, Yang ST, Huang CC, Kuo SC, Chung JG.
    Int J Oncol; 2012 Mar 14; 40(3):731-8. PubMed ID: 22021033
    [Abstract] [Full Text] [Related]

  • 17. Morin inhibits the growth of human leukemia HL-60 cells via cell cycle arrest and induction of apoptosis through mitochondria dependent pathway.
    Kuo HM, Chang LS, Lin YL, Lu HF, Yang JS, Lee JH, Chung JG.
    Anticancer Res; 2007 Mar 14; 27(1A):395-405. PubMed ID: 17352259
    [Abstract] [Full Text] [Related]

  • 18. Suppression of human prostate cancer cell growth by ciprofloxacin is associated with cell cycle arrest and apoptosis.
    Aranha O, Grignon R, Fernandes N, McDonnell TJ, Wood DP, Sarkar FH.
    Int J Oncol; 2003 Apr 14; 22(4):787-94. PubMed ID: 12632069
    [Abstract] [Full Text] [Related]

  • 19. Zanthoxylum ailanthoides Sieb and Zucc. extract inhibits growth and induces cell death through G2/M-phase arrest and activation of apoptotic signals in colo 205 human colon adenocarcinoma cells.
    Chou ST, Peng HY, Chang CT, Yang JS, Chung HK, Yang ST, Wood WG, Chung JG.
    Anticancer Res; 2011 May 14; 31(5):1667-76. PubMed ID: 21617225
    [Abstract] [Full Text] [Related]

  • 20. The novel antimicrotubule agent cryptophycin 52 (LY355703) induces apoptosis via multiple pathways in human prostate cancer cells.
    Drew L, Fine RL, Do TN, Douglas GP, Petrylak DP.
    Clin Cancer Res; 2002 Dec 14; 8(12):3922-32. PubMed ID: 12473608
    [Abstract] [Full Text] [Related]

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