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Journal Abstract Search

535 related items for PubMed ID: 21621885

  • 1. Molecular modelling studies on Arylthioindoles as potent inhibitors of tubulin polymerization.
    Coluccia A, Sabbadin D, Brancale A.
    Eur J Med Chem; 2011 Aug; 46(8):3519-25. PubMed ID: 21621885
    [Abstract] [Full Text] [Related]

  • 2. New arylthioindoles: potent inhibitors of tubulin polymerization. 2. Structure-activity relationships and molecular modeling studies.
    De Martino G, Edler MC, La Regina G, Coluccia A, Barbera MC, Barrow D, Nicholson RI, Chiosis G, Brancale A, Hamel E, Artico M, Silvestri R.
    J Med Chem; 2006 Feb 09; 49(3):947-54. PubMed ID: 16451061
    [Abstract] [Full Text] [Related]

  • 3. Indole molecules as inhibitors of tubulin polymerization: potential new anticancer agents.
    Patil SA, Patil R, Miller DD.
    Future Med Chem; 2012 Oct 09; 4(16):2085-115. PubMed ID: 23157240
    [Abstract] [Full Text] [Related]

  • 4. New indole-based chalconoids as tubulin-targeting antiproliferative agents.
    Mirzaei H, Shokrzadeh M, Modanloo M, Ziar A, Riazi GH, Emami S.
    Bioorg Chem; 2017 Dec 09; 75():86-98. PubMed ID: 28922629
    [Abstract] [Full Text] [Related]

  • 5. Application of GA-MLR for QSAR Modeling of the Arylthioindole Class of Tubulin Polymerization Inhibitors as Anticancer Agents.
    Ahmadi S, Habibpour E.
    Anticancer Agents Med Chem; 2017 Dec 09; 17(4):552-565. PubMed ID: 27528182
    [Abstract] [Full Text] [Related]

  • 6. Generation of ligand-based pharmacophore model and virtual screening for identification of novel tubulin inhibitors with potent anticancer activity.
    Chiang YK, Kuo CC, Wu YS, Chen CT, Coumar MS, Wu JS, Hsieh HP, Chang CY, Jseng HY, Wu MH, Leou JS, Song JS, Chang JY, Lyu PC, Chao YS, Wu SY.
    J Med Chem; 2009 Jul 23; 52(14):4221-33. PubMed ID: 19507860
    [Abstract] [Full Text] [Related]

  • 7. Electrostatic contributions to colchicine binding within tubulin isotypes.
    Huzil JT, Barakat K, Tuszynski JA.
    Electromagn Biol Med; 2009 Jul 23; 28(4):355-64. PubMed ID: 20017626
    [Abstract] [Full Text] [Related]

  • 8. 4- and 5-aroylindoles as novel classes of potent antitubulin agents.
    Liou JP, Wu CY, Hsieh HP, Chang CY, Chen CM, Kuo CC, Chang JY.
    J Med Chem; 2007 Sep 06; 50(18):4548-52. PubMed ID: 17685504
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors.
    Ouyang X, Chen X, Piatnitski EL, Kiselyov AS, He HY, Mao Y, Pattaropong V, Yu Y, Kim KH, Kincaid J, Smith L, Wong WC, Lee SP, Milligan DL, Malikzay A, Fleming J, Gerlak J, Deevi D, Doody JF, Chiang HH, Patel SN, Wang Y, Rolser RL, Kussie P, Labelle M, Tuma MC.
    Bioorg Med Chem Lett; 2005 Dec 01; 15(23):5154-9. PubMed ID: 16198562
    [Abstract] [Full Text] [Related]

  • 10. 7-Aroyl-aminoindoline-1-sulfonamides as a novel class of potent antitubulin agents.
    Chang JY, Hsieh HP, Chang CY, Hsu KS, Chiang YF, Chen CM, Kuo CC, Liou JP.
    J Med Chem; 2006 Nov 16; 49(23):6656-9. PubMed ID: 17154496
    [Abstract] [Full Text] [Related]

  • 11. Anti-mitotic activity of colchicine and the structural basis for its interaction with tubulin.
    Bhattacharyya B, Panda D, Gupta S, Banerjee M.
    Med Res Rev; 2008 Jan 16; 28(1):155-83. PubMed ID: 17464966
    [Abstract] [Full Text] [Related]

  • 12. Indole, a core nucleus for potent inhibitors of tubulin polymerization.
    Brancale A, Silvestri R.
    Med Res Rev; 2007 Mar 16; 27(2):209-38. PubMed ID: 16788980
    [Abstract] [Full Text] [Related]

  • 13. Arylthioindoles, potent inhibitors of tubulin polymerization.
    De Martino G, La Regina G, Coluccia A, Edler MC, Barbera MC, Brancale A, Wilcox E, Hamel E, Artico M, Silvestri R.
    J Med Chem; 2004 Dec 02; 47(25):6120-3. PubMed ID: 15566282
    [Abstract] [Full Text] [Related]

  • 14. Development of a novel class of tubulin inhibitors with promising anticancer activities.
    Xi J, Zhu X, Feng Y, Huang N, Luo G, Mao Y, Han X, Tian W, Wang G, Han X, Luo R, Huang Z, An J.
    Mol Cancer Res; 2013 Aug 02; 11(8):856-64. PubMed ID: 23666368
    [Abstract] [Full Text] [Related]

  • 15. 3-substituted 2-phenylimidazo[2,1-b]benzothiazoles: synthesis, anticancer activity, and inhibition of tubulin polymerization.
    Kamal A, Sultana F, Ramaiah MJ, Srikanth YV, Viswanath A, Kishor C, Sharma P, Pushpavalli SN, Addlagatta A, Pal-Bhadra M.
    ChemMedChem; 2012 Feb 06; 7(2):292-300. PubMed ID: 22241597
    [Abstract] [Full Text] [Related]

  • 16. Biological evaluation and molecular modelling study of podophyllotoxin derivatives as potent inhibitors of tubulin polymerization.
    Ma Y, Fang S, Li H, Han C, Lu Y, Zhao Y, Liu Y, Zhao C.
    Chem Biol Drug Des; 2013 Jul 06; 82(1):12-21. PubMed ID: 23786349
    [Abstract] [Full Text] [Related]

  • 17. Methoxy-substituted 3-formyl-2-phenylindoles inhibit tubulin polymerization.
    Gastpar R, Goldbrunner M, Marko D, von Angerer E.
    J Med Chem; 1998 Dec 03; 41(25):4965-72. PubMed ID: 9836614
    [Abstract] [Full Text] [Related]

  • 18. Synthesis, molecular modeling and biological evaluation of guanidine derivatives as novel antitubulin agents.
    Qian Y, Zhang HJ, Lv PC, Zhu HL.
    Bioorg Med Chem; 2010 Dec 01; 18(23):8218-25. PubMed ID: 21036623
    [Abstract] [Full Text] [Related]

  • 19. Structural insights into the design of indole derivatives as tubulin polymerization inhibitors.
    Li Y, Yang J, Niu L, Hu D, Li H, Chen L, Yu Y, Chen Q.
    FEBS Lett; 2020 Jan 01; 594(1):199-204. PubMed ID: 31369682
    [Abstract] [Full Text] [Related]

  • 20. Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.
    Wang G, Li C, He L, Lei K, Wang F, Pu Y, Yang Z, Cao D, Ma L, Chen J, Sang Y, Liang X, Xiang M, Peng A, Wei Y, Chen L.
    Bioorg Med Chem; 2014 Apr 01; 22(7):2060-79. PubMed ID: 24629450
    [Abstract] [Full Text] [Related]

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