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Journal Abstract Search

435 related items for PubMed ID: 21647838

  • 1. Hsp90 inhibitors and drugs from fragment and virtual screening.
    Roughley S, Wright L, Brough P, Massey A, Hubbard RE.
    Top Curr Chem; 2012; 317():61-82. PubMed ID: 21647838
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  • 6. Dihydroxylphenyl amides as inhibitors of the Hsp90 molecular chaperone.
    Kung PP, Funk L, Meng J, Collins M, Zhou JZ, Johnson MC, Ekker A, Wang J, Mehta P, Yin MJ, Rodgers C, Davies JF, Bayman E, Smeal T, Maegley KA, Gehring MR.
    Bioorg Med Chem Lett; 2008 Dec 01; 18(23):6273-8. PubMed ID: 18929486
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  • 10. Design strategies to target crystallographic waters applied to the Hsp90 molecular chaperone.
    Kung PP, Sinnema PJ, Richardson P, Hickey MJ, Gajiwala KS, Wang F, Huang B, McClellan G, Wang J, Maegley K, Bergqvist S, Mehta PP, Kania R.
    Bioorg Med Chem Lett; 2011 Jun 15; 21(12):3557-62. PubMed ID: 21612924
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  • 12. Structure-based virtual screening and optimization of modulators targeting Hsp90-Cdc37 interaction.
    Wang L, Li L, Zhou ZH, Jiang ZY, You QD, Xu XL.
    Eur J Med Chem; 2017 Aug 18; 136():63-73. PubMed ID: 28482218
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  • 14. Discovery of (2,4-dihydroxy-5-isopropylphenyl)-[5-(4-methylpiperazin-1-ylmethyl)-1,3-dihydroisoindol-2-yl]methanone (AT13387), a novel inhibitor of the molecular chaperone Hsp90 by fragment based drug design.
    Woodhead AJ, Angove H, Carr MG, Chessari G, Congreve M, Coyle JE, Cosme J, Graham B, Day PJ, Downham R, Fazal L, Feltell R, Figueroa E, Frederickson M, Lewis J, McMenamin R, Murray CW, O'Brien MA, Parra L, Patel S, Phillips T, Rees DC, Rich S, Smith DM, Trewartha G, Vinkovic M, Williams B, Woolford AJ.
    J Med Chem; 2010 Aug 26; 53(16):5956-69. PubMed ID: 20662534
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  • 16. Discovery of benzamide tetrahydro-4H-carbazol-4-ones as novel small molecule inhibitors of Hsp90.
    Barta TE, Veal JM, Rice JW, Partridge JM, Fadden RP, Ma W, Jenks M, Geng L, Hanson GJ, Huang KH, Barabasz AF, Foley BE, Otto J, Hall SE.
    Bioorg Med Chem Lett; 2008 Jun 15; 18(12):3517-21. PubMed ID: 18511277
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