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809 related items for PubMed ID: 21660448

  • 21. Withaferin A sensitizes TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP.
    Lee TJ, Um HJ, Min do S, Park JW, Choi KS, Kwon TK.
    Free Radic Biol Med; 2009 Jun 15; 46(12):1639-49. PubMed ID: 19345731
    [Abstract] [Full Text] [Related]

  • 22. COX-2 inhibitors sensitize human hepatocellular carcinoma cells to TRAIL-induced apoptosis.
    Yamanaka Y, Shiraki K, Inoue T, Miyashita K, Fuke H, Yamaguchi Y, Yamamoto N, Ito K, Sugimoto K, Nakano T.
    Int J Mol Med; 2006 Jul 15; 18(1):41-7. PubMed ID: 16786154
    [Abstract] [Full Text] [Related]

  • 23. Cisplatin sensitizes human hepatocellular carcinoma cells, but not hepatocytes and mesenchymal stem cells, to TRAIL within a therapeutic window partially depending on the upregulation of DR5.
    Zhang B, Shan H, Li D, Li ZR, Zhu KS, Jiang ZB, Huang MS.
    Oncol Rep; 2011 Feb 15; 25(2):461-8. PubMed ID: 21152876
    [Abstract] [Full Text] [Related]

  • 24. Sensitization of TRAIL-induced cell death by 20(S)-ginsenoside Rg3 via CHOP-mediated DR5 upregulation in human hepatocellular carcinoma cells.
    Lee JY, Jung KH, Morgan MJ, Kang YR, Lee HS, Koo GB, Hong SS, Kwon SW, Kim YS.
    Mol Cancer Ther; 2013 Mar 15; 12(3):274-85. PubMed ID: 23053497
    [Abstract] [Full Text] [Related]

  • 25. Guggulsterone sensitizes hepatoma cells to TRAIL-induced apoptosis through the induction of CHOP-dependent DR5: involvement of ROS-dependent ER-stress.
    Moon DO, Park SY, Choi YH, Ahn JS, Kim GY.
    Biochem Pharmacol; 2011 Dec 01; 82(11):1641-50. PubMed ID: 21903093
    [Abstract] [Full Text] [Related]

  • 26. Quercetin enhances apoptotic effect of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) in ovarian cancer cells through reactive oxygen species (ROS) mediated CCAAT enhancer-binding protein homologous protein (CHOP)-death receptor 5 pathway.
    Yi L, Zongyuan Y, Cheng G, Lingyun Z, Guilian Y, Wei G.
    Cancer Sci; 2014 May 01; 105(5):520-7. PubMed ID: 24612139
    [Abstract] [Full Text] [Related]

  • 27. Inhibition of euchromatin histone-lysine N-methyltransferase 2 sensitizes breast cancer cells to tumor necrosis factor-related apoptosis-inducing ligand through reactive oxygen species-mediated activating transcription factor 4-C/EBP homologous protein-death receptor 5 pathway activation.
    Kim SY, Hong M, Heo SH, Park S, Kwon TK, Sung YH, Oh Y, Lee S, Yi GS, Kim I.
    Mol Carcinog; 2018 Nov 01; 57(11):1492-1506. PubMed ID: 29964331
    [Abstract] [Full Text] [Related]

  • 28. CCAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction and ubiquitin/proteasome-mediated cellular FLICE-inhibitory protein down-regulation contribute to enhancement of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by dimethyl-celecoxib in human non small-cell lung cancer cells.
    Chen S, Liu X, Yue P, Schönthal AH, Khuri FR, Sun SY.
    Mol Pharmacol; 2007 Nov 01; 72(5):1269-79. PubMed ID: 17684158
    [Abstract] [Full Text] [Related]

  • 29. Partial contribution of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)/TRAIL receptor pathway to antitumor effects of interferon-alpha/5-fluorouracil against Hepatocellular Carcinoma.
    Yamamoto T, Nagano H, Sakon M, Wada H, Eguchi H, Kondo M, Damdinsuren B, Ota H, Nakamura M, Wada H, Marubashi S, Miyamoto A, Dono K, Umeshita K, Nakamori S, Yagita H, Monden M.
    Clin Cancer Res; 2004 Dec 01; 10(23):7884-95. PubMed ID: 15585621
    [Abstract] [Full Text] [Related]

  • 30. Curcumin sensitizes tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis through reactive oxygen species-mediated upregulation of death receptor 5 (DR5).
    Jung EM, Lim JH, Lee TJ, Park JW, Choi KS, Kwon TK.
    Carcinogenesis; 2005 Nov 01; 26(11):1905-13. PubMed ID: 15987718
    [Abstract] [Full Text] [Related]

  • 31. Upregulation of DR5 by proteasome inhibitors potently sensitizes glioma cells to TRAIL-induced apoptosis.
    Hetschko H, Voss V, Seifert V, Prehn JH, Kögel D.
    FEBS J; 2008 Apr 01; 275(8):1925-36. PubMed ID: 18341587
    [Abstract] [Full Text] [Related]

  • 32. Dovitinib sensitizes hepatocellular carcinoma cells to TRAIL and tigatuzumab, a novel anti-DR5 antibody, through SHP-1-dependent inhibition of STAT3.
    Chen KF, Chen HL, Liu CY, Tai WT, Ichikawa K, Chen PJ, Cheng AL.
    Biochem Pharmacol; 2012 Mar 15; 83(6):769-77. PubMed ID: 22230479
    [Abstract] [Full Text] [Related]

  • 33. Tunicamycin sensitizes human melanoma cells to tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by up-regulation of TRAIL-R2 via the unfolded protein response.
    Jiang CC, Chen LH, Gillespie S, Kiejda KA, Mhaidat N, Wang YF, Thorne R, Zhang XD, Hersey P.
    Cancer Res; 2007 Jun 15; 67(12):5880-8. PubMed ID: 17575157
    [Abstract] [Full Text] [Related]

  • 34. Casticin-induced apoptosis involves death receptor 5 upregulation in hepatocellular carcinoma cells.
    Yang J, Yang Y, Tian L, Sheng XF, Liu F, Cao JG.
    World J Gastroenterol; 2011 Oct 14; 17(38):4298-307. PubMed ID: 22090786
    [Abstract] [Full Text] [Related]

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  • 37. Histone deacetylase inhibitors upregulate death receptor 5/TRAIL-R2 and sensitize apoptosis induced by TRAIL/APO2-L in human malignant tumor cells.
    Nakata S, Yoshida T, Horinaka M, Shiraishi T, Wakada M, Sakai T.
    Oncogene; 2004 Aug 19; 23(37):6261-71. PubMed ID: 15208660
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