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Journal Abstract Search

604 related items for PubMed ID: 2166797

  • 1. Binding interactions of convulsant and anticonvulsant gamma-butyrolactones and gamma-thiobutyrolactones with the picrotoxin receptor.
    Holland KD, McKeon AC, Covey DF, Ferrendelli JA.
    J Pharmacol Exp Ther; 1990 Aug; 254(2):578-83. PubMed ID: 2166797
    [Abstract] [Full Text] [Related]

  • 2. Structure-activity studies of fluoroalkyl-substituted gamma-butyrolactone and gamma-thiobutyrolactone modulators of GABA(A) receptor function.
    Canney DJ, Lu HF, McKeon AC, Yoon KW, Xu K, Holland KD, Rothman SM, Ferrendelli JA, Covey DF.
    Bioorg Med Chem; 1998 Jan; 6(1):43-55. PubMed ID: 9502104
    [Abstract] [Full Text] [Related]

  • 3. Functional modulation of cerebral gamma-aminobutyric acidA receptor/benzodiazepine receptor/chloride ion channel complex with ethyl beta-carboline-3-carboxylate: presence of independent binding site for ethyl beta-carboline-3-carboxylate.
    Taguchi J, Kuriyama K.
    J Pharmacol Exp Ther; 1990 May; 253(2):558-66. PubMed ID: 2159999
    [Abstract] [Full Text] [Related]

  • 4. Dual modulation of the gamma-aminobutyric acid type A receptor/ionophore by alkyl-substituted gamma-butyrolactones.
    Holland KD, Mathews GC, Bolos-Sy AM, Tucker JB, Reddy PA, Covey DF, Ferrendelli JA, Rothman SM.
    Mol Pharmacol; 1995 Jun; 47(6):1217-23. PubMed ID: 7603463
    [Abstract] [Full Text] [Related]

  • 5. Physiological regulation of the picrotoxin receptor by gamma-butyrolactones and gamma-thiobutyrolactones in cultured hippocampal neurons.
    Holland KD, Ferrendelli JA, Covey DF, Rothman SM.
    J Neurosci; 1990 Jun; 10(6):1719-27. PubMed ID: 2355246
    [Abstract] [Full Text] [Related]

  • 6. Computer-assisted modeling of the picrotoxinin and gamma-butyrolactone receptor site.
    Klunk WE, Kalman BL, Ferrendelli JA, Covey DF.
    Mol Pharmacol; 1983 Mar; 23(2):511-8. PubMed ID: 6300653
    [Abstract] [Full Text] [Related]

  • 7. GABAA receptor subtypes: autoradiographic comparison of GABA, benzodiazepine, and convulsant binding sites in the rat central nervous system.
    Olsen RW, McCabe RT, Wamsley JK.
    J Chem Neuroanat; 1990 Mar; 3(1):59-76. PubMed ID: 2156526
    [Abstract] [Full Text] [Related]

  • 8. In vitro characterization of benzodiazepine receptor agonists, antagonists, inverse agonists and agonist/antagonists.
    Wood PL, Loo P, Braunwalder A, Yokoyama N, Cheney DL.
    J Pharmacol Exp Ther; 1984 Dec; 231(3):572-6. PubMed ID: 6094792
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and structure-activity studies of alkyl-substituted gamma-butyrolactones and gamma-thiobutyrolactones: ligands for the picrotoxin receptor.
    Canney DJ, Holland KD, Levine JA, McKeon AC, Ferrendelli JA, Covey DF.
    J Med Chem; 1991 Apr; 34(4):1460-7. PubMed ID: 1849999
    [Abstract] [Full Text] [Related]

  • 10. Loreclezole modulates [35S]t-butylbicyclophosphorothionate and [3H]flunitrazepam binding via a distinct site on the GABAA receptor complex.
    Xue BG, Friend JM, Gee KW.
    Eur J Pharmacol; 1996 Apr 04; 300(1-2):125-30. PubMed ID: 8741177
    [Abstract] [Full Text] [Related]

  • 11. Correlation of neuroactive steroid modulation of [35S]t-butylbicyclophosphorothionate and [3H]flunitrazepam binding and gamma-aminobutyric acidA receptor function.
    Hawkinson JE, Kimbrough CL, Belelli D, Lambert JJ, Purdy RH, Lan NC.
    Mol Pharmacol; 1994 Nov 04; 46(5):977-85. PubMed ID: 7969089
    [Abstract] [Full Text] [Related]

  • 12. Pharmacological subtypes of the gamma-aminobutyric acidA receptors defined by a gamma-aminobutyric acid analogue 4,5,6,7-tetrahydroisoxazolo[5,4-c] pyridin-3-ol and allosteric coupling: characterization using subunit-specific antibodies.
    Huh KH, Delorey TM, Endo S, Olsen RW.
    Mol Pharmacol; 1995 Oct 04; 48(4):666-75. PubMed ID: 7476892
    [Abstract] [Full Text] [Related]

  • 13. Convulsant and anticonvulsant cyclopentanones and cyclohexanones.
    Holland KD, Naritoku DK, McKeon AC, Ferrendelli JA, Covey DF.
    Mol Pharmacol; 1990 Jan 04; 37(1):98-103. PubMed ID: 2153913
    [Abstract] [Full Text] [Related]

  • 14. Effects of picrotoxin treatment on GABAA receptor supramolecular complexes in rat brain.
    Ito Y, Lim DK, Nabeshima T, Ho IK.
    J Neurochem; 1989 Apr 04; 52(4):1064-70. PubMed ID: 2538560
    [Abstract] [Full Text] [Related]

  • 15. Comparison of interactions of [3H]muscimol, t-butylbicyclophosphoro[35S]thionate, and [3H]flunitrazepam with cloned gamma-aminobutyric acidA receptors of the alpha 1 beta 2 and alpha 1 beta 2 gamma 2 subtypes.
    Pregenzer JF, Im WB, Carter DB, Thomsen DR.
    Mol Pharmacol; 1993 May 04; 43(5):801-6. PubMed ID: 8388991
    [Abstract] [Full Text] [Related]

  • 16. Characterization of gamma-aminobutyrate type A receptors with atypical coupling between agonist and convulsant binding sites in discrete brain regions.
    Sinkkonen ST, Uusi-Oukari M, Tupala E, Särkioja T, Tiihonen J, Panula P, Lüddens H, Korpi ER.
    Brain Res Mol Brain Res; 2001 Jan 31; 86(1-2):168-78. PubMed ID: 11165383
    [Abstract] [Full Text] [Related]

  • 17. 3 alpha-Hydroxy-3 beta-trifluoromethyl-5 alpha-pregnan-20-one (Co 2-1970): a partial agonist at the neuroactive steroid site of the gamma-aminobutyric acidA receptor.
    Hawkinson JE, Drewe JA, Kimbrough CL, Chen JS, Hogenkamp DJ, Lan NC, Gee KW, Shen KZ, Whittemore ER, Woodward RM.
    Mol Pharmacol; 1996 May 31; 49(5):897-906. PubMed ID: 8622640
    [Abstract] [Full Text] [Related]

  • 18. Convulsant and anti-convulsant gammabutyrolactones bind at the picrotoxinin/T-butylbicyclophosphorothionate (TBPS) receptor.
    Levine JA, Ferrendelli JA, Covey DF.
    Biochem Pharmacol; 1985 Dec 01; 34(23):4187-90. PubMed ID: 2998401
    [No Abstract] [Full Text] [Related]

  • 19. Clathrin-coated vesicles from bovine brain contain uncoupled GABAA receptors.
    Tehrani MH, Baumgartner BJ, Barnes EM.
    Brain Res; 1997 Nov 21; 776(1-2):195-203. PubMed ID: 9439813
    [Abstract] [Full Text] [Related]

  • 20. Anxiolytic cyclopyrrolone drugs allosterically modulate the binding of [35S]t-butylbicyclophosphorothionate to the benzodiazepine/gamma-aminobutyric acid-A receptor/chloride anionophore complex.
    Trifiletti RR, Snowman AM, Snyder SH.
    Mol Pharmacol; 1984 Nov 21; 26(3):470-6. PubMed ID: 6149458
    [Abstract] [Full Text] [Related]

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