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238 related items for PubMed ID: 21671255

  • 1. Neuroprotective effect of guanosine against glutamate-induced cell death in rat hippocampal slices is mediated by the phosphatidylinositol-3 kinase/Akt/ glycogen synthase kinase 3β pathway activation and inducible nitric oxide synthase inhibition.
    Molz S, Dal-Cim T, Budni J, Martín-de-Saavedra MD, Egea J, Romero A, del Barrio L, Rodrigues AL, López MG, Tasca CI.
    J Neurosci Res; 2011 Sep; 89(9):1400-8. PubMed ID: 21671255
    [Abstract] [Full Text] [Related]

  • 2. Antidepressant-like and neuroprotective effects of Aloysia gratissima: investigation of involvement of L-arginine-nitric oxide-cyclic guanosine monophosphate pathway.
    Zeni AL, Zomkowski AD, Dal-Cim T, Maraschin M, Rodrigues AL, Tasca CI.
    J Ethnopharmacol; 2011 Sep 01; 137(1):864-74. PubMed ID: 21767626
    [Abstract] [Full Text] [Related]

  • 3. Folic Acid Protects Against Glutamate-Induced Excitotoxicity in Hippocampal Slices Through a Mechanism that Implicates Inhibition of GSK-3β and iNOS.
    Budni J, Molz S, Dal-Cim T, Martín-de-Saavedra MD, Egea J, Lopéz MG, Tasca CI, Rodrigues ALS.
    Mol Neurobiol; 2018 Feb 01; 55(2):1580-1589. PubMed ID: 28185129
    [Abstract] [Full Text] [Related]

  • 4. Guanosine is neuroprotective against oxygen/glucose deprivation in hippocampal slices via large conductance Ca²+-activated K+ channels, phosphatidilinositol-3 kinase/protein kinase B pathway activation and glutamate uptake.
    Dal-Cim T, Martins WC, Santos AR, Tasca CI.
    Neuroscience; 2011 Jun 02; 183():212-20. PubMed ID: 21435378
    [Abstract] [Full Text] [Related]

  • 5. Guanosine controls inflammatory pathways to afford neuroprotection of hippocampal slices under oxygen and glucose deprivation conditions.
    Dal-Cim T, Ludka FK, Martins WC, Reginato C, Parada E, Egea J, López MG, Tasca CI.
    J Neurochem; 2013 Aug 02; 126(4):437-50. PubMed ID: 23713463
    [Abstract] [Full Text] [Related]

  • 6. The neuroprotective action of pyrroloquinoline quinone against glutamate-induced apoptosis in hippocampal neurons is mediated through the activation of PI3K/Akt pathway.
    Zhang Q, Shen M, Ding M, Shen D, Ding F.
    Toxicol Appl Pharmacol; 2011 Apr 01; 252(1):62-72. PubMed ID: 21320517
    [Abstract] [Full Text] [Related]

  • 7. alpha-Amino-3-hydroxy-5-methyl-4-isoxazole propionate attenuates glutamate-induced caspase-3 cleavage via regulation of glycogen synthase kinase 3beta.
    Nishimoto T, Kihara T, Akaike A, Niidome T, Sugimoto H.
    J Neurosci Res; 2008 Apr 01; 86(5):1096-105. PubMed ID: 18041091
    [Abstract] [Full Text] [Related]

  • 8. Mechanism of neuroprotection by donepezil pretreatment in rat cortical neurons chronically treated with donepezil.
    Takada-Takatori Y, Kume T, Ohgi Y, Izumi Y, Niidome T, Fujii T, Sugimoto H, Akaike A.
    J Neurosci Res; 2008 Dec 01; 86(16):3575-83. PubMed ID: 18655200
    [Abstract] [Full Text] [Related]

  • 9. GMP prevents excitotoxicity mediated by NMDA receptor activation but not by reversal activity of glutamate transporters in rat hippocampal slices.
    Molz S, Tharine DC, Decker H, Tasca CI.
    Brain Res; 2008 Sep 22; 1231():113-20. PubMed ID: 18655777
    [Abstract] [Full Text] [Related]

  • 10. Neuroprotective effects of linarin through activation of the PI3K/Akt pathway in amyloid-β-induced neuronal cell death.
    Lou H, Fan P, Perez RG, Lou H.
    Bioorg Med Chem; 2011 Jul 01; 19(13):4021-7. PubMed ID: 21652214
    [Abstract] [Full Text] [Related]

  • 11. NMDA neuroprotection against a phosphatidylinositol-3 kinase inhibitor, LY294002 by NR2B-mediated suppression of glycogen synthase kinase-3beta-induced apoptosis.
    Habas A, Kharebava G, Szatmari E, Hetman M.
    J Neurochem; 2006 Jan 01; 96(2):335-48. PubMed ID: 16300633
    [Abstract] [Full Text] [Related]

  • 12. Ghrelin protects spinal cord motoneurons against chronic glutamate-induced excitotoxicity via ERK1/2 and phosphatidylinositol-3-kinase/Akt/glycogen synthase kinase-3β pathways.
    Lim E, Lee S, Li E, Kim Y, Park S.
    Exp Neurol; 2011 Jul 01; 230(1):114-22. PubMed ID: 21530509
    [Abstract] [Full Text] [Related]

  • 13. Sustained activation of Akt by melatonin contributes to the protection against kainic acid-induced neuronal death in hippocampus.
    Lee SH, Chun W, Kong PJ, Han JA, Cho BP, Kwon OY, Lee HJ, Kim SS.
    J Pineal Res; 2006 Jan 01; 40(1):79-85. PubMed ID: 16313502
    [Abstract] [Full Text] [Related]

  • 14. Mechanism of guanosine-induced neuroprotection in rat hippocampal slices submitted to oxygen-glucose deprivation.
    Oleskovicz SP, Martins WC, Leal RB, Tasca CI.
    Neurochem Int; 2008 Feb 01; 52(3):411-8. PubMed ID: 17822807
    [Abstract] [Full Text] [Related]

  • 15. Protective effect of dopamine D2 agonists in cortical neurons via the phosphatidylinositol 3 kinase cascade.
    Kihara T, Shimohama S, Sawada H, Honda K, Nakamizo T, Kanki R, Yamashita H, Akaike A.
    J Neurosci Res; 2002 Nov 01; 70(3):274-82. PubMed ID: 12391586
    [Abstract] [Full Text] [Related]

  • 16. Neuroprotection by JM-20 against oxygen-glucose deprivation in rat hippocampal slices: Involvement of the Akt/GSK-3β pathway.
    Ramírez-Sánchez J, Simões Pires EN, Nuñez-Figueredo Y, Pardo-Andreu GL, Fonseca-Fonseca LA, Ruiz-Reyes A, Ochoa-Rodríguez E, Verdecia-Reyes Y, Delgado-Hernández R, Souza DO, Salbego C.
    Neurochem Int; 2015 Nov 01; 90():215-23. PubMed ID: 26361722
    [Abstract] [Full Text] [Related]

  • 17. Protective role of melatonin in domoic acid-induced neuronal damage in the hippocampus of adult rats.
    Ananth C, Gopalakrishnakone P, Kaur C.
    Hippocampus; 2003 Nov 01; 13(3):375-87. PubMed ID: 12722978
    [Abstract] [Full Text] [Related]

  • 18. Activation of the Akt/GSK3beta signaling pathway mediates survival of vulnerable hippocampal neurons after transient global cerebral ischemia in rats.
    Endo H, Nito C, Kamada H, Nishi T, Chan PH.
    J Cereb Blood Flow Metab; 2006 Dec 01; 26(12):1479-89. PubMed ID: 16538228
    [Abstract] [Full Text] [Related]

  • 19. Insulin-like growth factor 1 prevents neuronal cell death induced by corticosterone through activation of the PI3k/Akt pathway.
    Nitta A, Zheng WH, Quirion R.
    J Neurosci Res; 2004 Apr 01; 76(1):98-103. PubMed ID: 15048933
    [Abstract] [Full Text] [Related]

  • 20. Lithium activates the Wnt and phosphatidylinositol 3-kinase Akt signaling pathways to promote cell survival in the absence of soluble survival factors.
    Sinha D, Wang Z, Ruchalski KL, Levine JS, Krishnan S, Lieberthal W, Schwartz JH, Borkan SC.
    Am J Physiol Renal Physiol; 2005 Apr 01; 288(4):F703-13. PubMed ID: 15572521
    [Abstract] [Full Text] [Related]


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