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257 related items for PubMed ID: 21673128
1. Culture period-dependent changes in the uptake of transporter substrates in sandwich-cultured rat and human hepatocytes. Kotani N, Maeda K, Watanabe T, Hiramatsu M, Gong LK, Bi YA, Takezawa T, Kusuhara H, Sugiyama Y. Drug Metab Dispos; 2011 Sep; 39(9):1503-10. PubMed ID: 21673128 [Abstract] [Full Text] [Related]
2. Characterization of digoxin uptake in sandwich-cultured human hepatocytes. Kimoto E, Chupka J, Xiao Y, Bi YA, Duignan DB. Drug Metab Dispos; 2011 Jan; 39(1):47-53. PubMed ID: 20926619 [Abstract] [Full Text] [Related]
3. Uptake of rosuvastatin by isolated rat hepatocytes: comparison with pravastatin. Nezasa K, Higaki K, Takeuchi M, Nakano M, Koike M. Xenobiotica; 2003 Apr; 33(4):379-88. PubMed ID: 12745873 [Abstract] [Full Text] [Related]
4. In vivo biliary clearance should be predicted by intrinsic biliary clearance in sandwich-cultured hepatocytes. Nakakariya M, Ono M, Amano N, Moriwaki T, Maeda K, Sugiyama Y. Drug Metab Dispos; 2012 Mar; 40(3):602-9. PubMed ID: 22190695 [Abstract] [Full Text] [Related]
5. Effect of plasma protein binding on in vitro-in vivo correlation of biliary excretion of drugs evaluated by sandwich-cultured rat hepatocytes. Fukuda H, Ohashi R, Tsuda-Tsukimoto M, Tamai I. Drug Metab Dispos; 2008 Jul; 36(7):1275-82. PubMed ID: 18388177 [Abstract] [Full Text] [Related]
6. Drug and bile acid transporters in rosuvastatin hepatic uptake: function, expression, and pharmacogenetics. Ho RH, Tirona RG, Leake BF, Glaeser H, Lee W, Lemke CJ, Wang Y, Kim RB. Gastroenterology; 2006 May; 130(6):1793-806. PubMed ID: 16697742 [Abstract] [Full Text] [Related]
7. Use of cryopreserved human hepatocytes in sandwich culture to measure hepatobiliary transport. Bi YA, Kazolias D, Duignan DB. Drug Metab Dispos; 2006 Sep; 34(9):1658-65. PubMed ID: 16782767 [Abstract] [Full Text] [Related]
8. Estimation of transporters involved in the hepatobiliary transport of TA-0201CA using sandwich-cultured rat hepatocytes from normal and multidrug resistance-associated protein 2-deficient rats. Fukuda H, Ohashi R, Ohashi N, Yabuuchi H, Tamai I. Drug Metab Dispos; 2010 Sep; 38(9):1505-13. PubMed ID: 20538722 [Abstract] [Full Text] [Related]
10. Differential modulation of cytochrome P450 activity and the effect of 1-aminobenzotriazole on hepatic transport in sandwich-cultured human hepatocytes. Kimoto E, Walsky R, Zhang H, Bi YA, Whalen KM, Yang YS, Linder C, Xiao Y, Iseki K, Fenner KS, El-Kattan AF, Lai Y. Drug Metab Dispos; 2012 Feb; 40(2):407-11. PubMed ID: 22031626 [Abstract] [Full Text] [Related]
11. Determination of OATP-, NTCP- and OCT-mediated substrate uptake activities in individual and pooled batches of cryopreserved human hepatocytes. De Bruyn T, Ye ZW, Peeters A, Sahi J, Baes M, Augustijns PF, Annaert PP. Eur J Pharm Sci; 2011 Jul 17; 43(4):297-307. PubMed ID: 21605667 [Abstract] [Full Text] [Related]
15. Automated applications of sandwich-cultured hepatocytes in the evaluation of hepatic drug transport. Perry CH, Smith WR, St Claire RL, Brouwer KR. J Biomol Screen; 2011 Apr 17; 16(4):427-35. PubMed ID: 21393626 [Abstract] [Full Text] [Related]
16. Functional characterization of mouse organic anion transporting peptide 1a4 in the uptake and efflux of drugs across the blood-brain barrier. Ose A, Kusuhara H, Endo C, Tohyama K, Miyajima M, Kitamura S, Sugiyama Y. Drug Metab Dispos; 2010 Jan 17; 38(1):168-76. PubMed ID: 19833843 [Abstract] [Full Text] [Related]
18. An experimental approach to evaluate the impact of impaired transport function on hepatobiliary drug disposition using Mrp2-deficient TR- rat sandwich-cultured hepatocytes in combination with Bcrp knockdown. Yang K, Pfeifer ND, Hardwick RN, Yue W, Stewart PW, Brouwer KL. Mol Pharm; 2014 Mar 03; 11(3):766-75. PubMed ID: 24410402 [Abstract] [Full Text] [Related]