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Journal Abstract Search


437 related items for PubMed ID: 21673130

  • 1. Hepatic UDP-glucuronosyltransferase is responsible for eslicarbazepine glucuronidation.
    Loureiro AI, Fernandes-Lopes C, Bonifácio MJ, Wright LC, Soares-da-Silva P.
    Drug Metab Dispos; 2011 Sep; 39(9):1486-94. PubMed ID: 21673130
    [Abstract] [Full Text] [Related]

  • 2. Glucuronidation of edaravone by human liver and kidney microsomes: biphasic kinetics and identification of UGT1A9 as the major UDP-glucuronosyltransferase isoform.
    Ma L, Sun J, Peng Y, Zhang R, Shao F, Hu X, Zhu J, Wang X, Cheng X, Zhu Y, Wan P, Feng D, Wu H, Wang G.
    Drug Metab Dispos; 2012 Apr; 40(4):734-41. PubMed ID: 22238289
    [Abstract] [Full Text] [Related]

  • 3. Regioselective glucuronidation of denopamine: marked species differences and identification of human udp-glucuronosyltransferase isoform.
    Kaji H, Kume T.
    Drug Metab Dispos; 2005 Mar; 33(3):403-12. PubMed ID: 15608137
    [Abstract] [Full Text] [Related]

  • 4. Identification of UDP-glucuronosyltransferases responsible for the glucuronidation of darexaban, an oral factor Xa inhibitor, in human liver and intestine.
    Shiraga T, Yajima K, Suzuki K, Suzuki K, Hashimoto T, Iwatsubo T, Miyashita A, Usui T.
    Drug Metab Dispos; 2012 Feb; 40(2):276-82. PubMed ID: 22031623
    [Abstract] [Full Text] [Related]

  • 5. Carboxyl-glucuronidation of mitiglinide by human UDP-glucuronosyltransferases.
    Yu L, Lu S, Lin Y, Zeng S.
    Biochem Pharmacol; 2007 Jun 01; 73(11):1842-51. PubMed ID: 17359941
    [Abstract] [Full Text] [Related]

  • 6. Trans-3'-hydroxycotinine O- and N-glucuronidations in human liver microsomes.
    Yamanaka H, Nakajima M, Katoh M, Kanoh A, Tamura O, Ishibashi H, Yokoi T.
    Drug Metab Dispos; 2005 Jan 01; 33(1):23-30. PubMed ID: 15470160
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  • 7. Bovine serum albumin decreases Km values of human UDP-glucuronosyltransferases 1A9 and 2B7 and increases Vmax values of UGT1A9.
    Manevski N, Moreolo PS, Yli-Kauhaluoma J, Finel M.
    Drug Metab Dispos; 2011 Nov 01; 39(11):2117-29. PubMed ID: 21856742
    [Abstract] [Full Text] [Related]

  • 8. Identification of human UGT2B7 as the major isoform involved in the O-glucuronidation of chloramphenicol.
    Chen M, LeDuc B, Kerr S, Howe D, Williams DA.
    Drug Metab Dispos; 2010 Mar 01; 38(3):368-75. PubMed ID: 20008037
    [Abstract] [Full Text] [Related]

  • 9. The "albumin effect" and drug glucuronidation: bovine serum albumin and fatty acid-free human serum albumin enhance the glucuronidation of UDP-glucuronosyltransferase (UGT) 1A9 substrates but not UGT1A1 and UGT1A6 activities.
    Rowland A, Knights KM, Mackenzie PI, Miners JO.
    Drug Metab Dispos; 2008 Jun 01; 36(6):1056-62. PubMed ID: 18362158
    [Abstract] [Full Text] [Related]

  • 10. The UDP-glucuronosyltransferase 2B7 isozyme is responsible for gemfibrozil glucuronidation in the human liver.
    Mano Y, Usui T, Kamimura H.
    Drug Metab Dispos; 2007 Nov 01; 35(11):2040-4. PubMed ID: 17670842
    [Abstract] [Full Text] [Related]

  • 11. Stereoselective glucuronidation of propranolol in human and cynomolgus monkey liver microsomes: role of human hepatic UDP-glucuronosyltransferase isoforms, UGT1A9, UGT2B4 and UGT2B7.
    Hanioka N, Hayashi K, Shimizudani T, Nagaoka K, Koeda A, Naito S, Narimatsu S.
    Pharmacology; 2008 Nov 01; 82(4):293-303. PubMed ID: 18936551
    [Abstract] [Full Text] [Related]

  • 12. Human UDP-glucuronosyltransferase isoforms involved in haloperidol glucuronidation and quantitative estimation of their contribution.
    Kato Y, Nakajima M, Oda S, Fukami T, Yokoi T.
    Drug Metab Dispos; 2012 Feb 01; 40(2):240-8. PubMed ID: 22028316
    [Abstract] [Full Text] [Related]

  • 13. Optimization of Experimental Conditions of Automated Glucuronidation Assays in Human Liver Microsomes Using a Cocktail Approach and Ultra-High Performance Liquid Chromatography-Tandem Mass Spectrometry.
    Badée J, Qiu N, Parrott N, Collier AC, Schmidt S, Fowler S.
    Drug Metab Dispos; 2019 Feb 01; 47(2):124-134. PubMed ID: 30478159
    [Abstract] [Full Text] [Related]

  • 14. Assessment of UDP-glucuronosyltransferase catalyzed formation of Picroside II glucuronide in microsomes of different species and recombinant UGTs.
    Li T, Zheng Y, Fu F, Ji H, Chen X, Zhao Y, Zhao D, Li N, Zhang L.
    Xenobiotica; 2011 Jul 01; 41(7):530-7. PubMed ID: 21524190
    [Abstract] [Full Text] [Related]

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  • 19. Characterization of 1'-hydroxymidazolam glucuronidation in human liver microsomes.
    Zhu B, Bush D, Doss GA, Vincent S, Franklin RB, Xu S.
    Drug Metab Dispos; 2008 Feb 01; 36(2):331-8. PubMed ID: 17998299
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