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Journal Abstract Search

424 related items for PubMed ID: 21675871

  • 1. Rat primary hepatocytes show enhanced performance and sensitivity to acetaminophen during three-dimensional culture on a polystyrene scaffold designed for routine use.
    Schutte M, Fox B, Baradez MO, Devonshire A, Minguez J, Bokhari M, Przyborski S, Marshall D.
    Assay Drug Dev Technol; 2011 Oct; 9(5):475-86. PubMed ID: 21675871
    [Abstract] [Full Text] [Related]

  • 2. Evaluation of drug toxicity with hepatocytes cultured in a micro-space cell culture system.
    Nakamura K, Mizutani R, Sanbe A, Enosawa S, Kasahara M, Nakagawa A, Ejiri Y, Murayama N, Miyamoto Y, Torii T, Kusakawa S, Yamauchi J, Fukuda M, Yamazaki H, Tanoue A.
    J Biosci Bioeng; 2011 Jan; 111(1):78-84. PubMed ID: 20837398
    [Abstract] [Full Text] [Related]

  • 3. A long-term three dimensional liver co-culture system for improved prediction of clinically relevant drug-induced hepatotoxicity.
    Kostadinova R, Boess F, Applegate D, Suter L, Weiser T, Singer T, Naughton B, Roth A.
    Toxicol Appl Pharmacol; 2013 Apr 01; 268(1):1-16. PubMed ID: 23352505
    [Abstract] [Full Text] [Related]

  • 4. The suitability of hepatocyte culture models to study various aspects of drug metabolism.
    Nussler AK, Wang A, Neuhaus P, Fischer J, Yuan J, Liu L, Zeilinger K, Gerlach J, Arnold PJ, Albrecht W.
    ALTEX; 2001 Apr 01; 18(2):91-101. PubMed ID: 11378681
    [Abstract] [Full Text] [Related]

  • 5. Interspecies differences in acetaminophen sensitivity of human, rat, and mouse primary hepatocytes.
    Jemnitz K, Veres Z, Monostory K, Kóbori L, Vereczkey L.
    Toxicol In Vitro; 2008 Jun 01; 22(4):961-7. PubMed ID: 18346862
    [Abstract] [Full Text] [Related]

  • 6. Three-dimensional HepaRG model as an attractive tool for toxicity testing.
    Leite SB, Wilk-Zasadna I, Zaldivar JM, Airola E, Reis-Fernandes MA, Mennecozzi M, Guguen-Guillouzo C, Chesne C, Guillou C, Alves PM, Coecke S.
    Toxicol Sci; 2012 Nov 01; 130(1):106-16. PubMed ID: 22843569
    [Abstract] [Full Text] [Related]

  • 7. Primary rat hepatocyte culture on 3D nanofibrous polymer scaffolds for toxicology and pharmaceutical research.
    Bierwolf J, Lutgehetmann M, Feng K, Erbes J, Deichmann S, Toronyi E, Stieglitz C, Nashan B, Ma PX, Pollok JM.
    Biotechnol Bioeng; 2011 Jan 01; 108(1):141-50. PubMed ID: 20824672
    [Abstract] [Full Text] [Related]

  • 8. Transport, metabolism, and hepatotoxicity of flutamide, drug-drug interaction with acetaminophen involving phase I and phase II metabolites.
    Kostrubsky SE, Strom SC, Ellis E, Nelson SD, Mutlib AE.
    Chem Res Toxicol; 2007 Oct 01; 20(10):1503-12. PubMed ID: 17900172
    [Abstract] [Full Text] [Related]

  • 9. In vitro system for the prediction of hepatotoxic effects in primary hepatocytes.
    Thedinga E, Ullrich A, Drechsler S, Niendorf R, Kob A, Runge D, Keuer A, Freund I, Lehmann M, Ehret R.
    ALTEX; 2007 Oct 01; 24(1):22-34. PubMed ID: 17361318
    [Abstract] [Full Text] [Related]

  • 10. In vitro evaluation of hepatotoxic drugs in human hepatocytes from multiple donors: Identification of P450 activity as a potential risk factor for drug-induced liver injuries.
    Utkarsh D, Loretz C, Li AP.
    Chem Biol Interact; 2016 Aug 05; 255():12-22. PubMed ID: 26718876
    [Abstract] [Full Text] [Related]

  • 11. Serum-free collagen sandwich cultures of adult rat hepatocytes maintain liver-like properties long term: a valuable model for in vitro toxicity and drug-drug interaction studies.
    Tuschl G, Hrach J, Walter Y, Hewitt PG, Mueller SO.
    Chem Biol Interact; 2009 Sep 14; 181(1):124-37. PubMed ID: 19482013
    [Abstract] [Full Text] [Related]

  • 12. Extending hepatocyte functionality for drug-testing applications using high-viscosity alginate-encapsulated three-dimensional cultures in bioreactors.
    Miranda JP, Rodrigues A, Tostões RM, Leite S, Zimmerman H, Carrondo MJ, Alves PM.
    Tissue Eng Part C Methods; 2010 Dec 14; 16(6):1223-32. PubMed ID: 20184401
    [Abstract] [Full Text] [Related]

  • 13. Three-dimensional chitosan scaffold-based MCF-7 cell culture for the determination of the cytotoxicity of tamoxifen.
    Dhiman HK, Ray AR, Panda AK.
    Biomaterials; 2005 Mar 14; 26(9):979-86. PubMed ID: 15369686
    [Abstract] [Full Text] [Related]

  • 14. Perfusion enhanced polydimethylsiloxane based scaffold cell culturing system for multi-well drug screening platform.
    Tania M, Hsu MN, Png SN, Leo HL, Toh GW, Birgersson E.
    Biotechnol Prog; 2014 Mar 14; 30(2):418-28. PubMed ID: 24399780
    [Abstract] [Full Text] [Related]

  • 15. Thermo-responsive non-woven scaffolds for "smart" 3D cell culture.
    Rossouw CL, Chetty A, Moolman FS, Birkholtz LM, Hoppe H, Mancama DT.
    Biotechnol Bioeng; 2012 Aug 14; 109(8):2147-58. PubMed ID: 22367720
    [Abstract] [Full Text] [Related]

  • 16. Small scale rat hepatocyte primary culture with applications for screening hepatoprotective substances.
    Nakagiri R, Oda H, Kamiya T.
    Biosci Biotechnol Biochem; 2003 Aug 14; 67(8):1629-35. PubMed ID: 12951493
    [Abstract] [Full Text] [Related]

  • 17. In-depth physiological characterization of primary human hepatocytes in a 3D hollow-fiber bioreactor.
    Mueller D, Tascher G, Müller-Vieira U, Knobeloch D, Nuessler AK, Zeilinger K, Heinzle E, Noor F.
    J Tissue Eng Regen Med; 2011 Aug 14; 5(8):e207-18. PubMed ID: 21442764
    [Abstract] [Full Text] [Related]

  • 18. Effects of cell culture conditions on primary rat hepatocytes-cell morphology and differential gene expression.
    Tuschl G, Mueller SO.
    Toxicology; 2006 Feb 01; 218(2-3):205-15. PubMed ID: 16337326
    [Abstract] [Full Text] [Related]

  • 19. Agar-gelatin hybrid sponge-induced three-dimensional in vitro 'liver-like' HepG2 spheroids for the evaluation of drug cytotoxicity.
    Verma P, Verma V, Ray P, Ray AR.
    J Tissue Eng Regen Med; 2009 Jul 01; 3(5):368-76. PubMed ID: 19408239
    [Abstract] [Full Text] [Related]

  • 20. Primary culture of rat hepatocytes in 96-well plates: effects of extracellular matrix configuration on cytochrome P450 enzyme activity and inducibility, and its application in in vitro cytotoxicity screening.
    Mingoia RT, Nabb DL, Yang CH, Han X.
    Toxicol In Vitro; 2007 Feb 01; 21(1):165-73. PubMed ID: 17141466
    [Abstract] [Full Text] [Related]

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