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Journal Abstract Search

212 related items for PubMed ID: 21676879

  • 1. Missense mutation in APOC3 within the C-terminal lipid binding domain of human ApoC-III results in impaired assembly and secretion of triacylglycerol-rich very low density lipoproteins: evidence that ApoC-III plays a major role in the formation of lipid precursors within the microsomal lumen.
    Qin W, Sundaram M, Wang Y, Zhou H, Zhong S, Chang CC, Manhas S, Yao EF, Parks RJ, McFie PJ, Stone SJ, Jiang ZG, Wang C, Figeys D, Jia W, Yao Z.
    J Biol Chem; 2011 Aug 05; 286(31):27769-80. PubMed ID: 21676879
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  • 3. Expression of apolipoprotein C-III in McA-RH7777 cells enhances VLDL assembly and secretion under lipid-rich conditions.
    Sundaram M, Zhong S, Bou Khalil M, Links PH, Zhao Y, Iqbal J, Hussain MM, Parks RJ, Wang Y, Yao Z.
    J Lipid Res; 2010 Jan 05; 51(1):150-61. PubMed ID: 19622837
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  • 4. Human apolipoprotein C-III - a new intrahepatic protein factor promoting assembly and secretion of very low density lipoproteins.
    Yao Z.
    Cardiovasc Hematol Disord Drug Targets; 2012 Dec 05; 12(2):133-40. PubMed ID: 23030451
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  • 5. A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels.
    Khetarpal SA, Zeng X, Millar JS, Vitali C, Somasundara AVH, Zanoni P, Landro JA, Barucci N, Zavadoski WJ, Sun Z, de Haard H, Toth IV, Peloso GM, Natarajan P, Cuchel M, Lund-Katz S, Phillips MC, Tall AR, Kathiresan S, DaSilva-Jardine P, Yates NA, Rader DJ.
    Nat Med; 2017 Sep 05; 23(9):1086-1094. PubMed ID: 28825717
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  • 9. The activity of microsomal triglyceride transfer protein is essential for accumulation of triglyceride within microsomes in McA-RH7777 cells. A unified model for the assembly of very low density lipoproteins.
    Wang Y, Tran K, Yao Z.
    J Biol Chem; 1999 Sep 24; 274(39):27793-800. PubMed ID: 10488124
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  • 12. Microsome-associated lumenal lipid droplets in the regulation of lipoprotein secretion.
    Yao Z, Zhou H, Figeys D, Wang Y, Sundaram M.
    Curr Opin Lipidol; 2013 Apr 24; 24(2):160-70. PubMed ID: 23123764
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  • 13. Suppression of cytosolic triacylglycerol recruitment for very low density lipoprotein assembly by inactivation of microsomal triglyceride transfer protein results in a delayed removal of apoB-48 and apoB-100 from microsomal and Golgi membranes of primary rat hepatocytes.
    Hebbachi AM, Brown AM, Gibbons GF.
    J Lipid Res; 1999 Oct 24; 40(10):1758-68. PubMed ID: 10508195
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  • 15. [THE LIPOLYSIS IN PHYLOGENETICALLY EARLY LIPOPROTEINS OF LOW DENSITY AND MORE LATER LIPOPROTEINS OF VERY LOW DENSITY: FUNCTION AND DIAGNOSTIC VALUE OF APOE AND APOC-III].
    Rozhkova TA, Titov VN, Amelyushkina VA, Kaba SI, Kukhartchuk VV.
    Klin Lab Diagn; 2015 Dec 24; 60(12):4-14. PubMed ID: 27032246
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  • 16. The apolipoprotein C-III (Gln38Lys) variant associated with human hypertriglyceridemia is a gain-of-function mutation.
    Sundaram M, Curtis KR, Amir Alipour M, LeBlond ND, Margison KD, Yaworski RA, Parks RJ, McIntyre AD, Hegele RA, Fullerton MD, Yao Z.
    J Lipid Res; 2017 Nov 24; 58(11):2188-2196. PubMed ID: 28887372
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  • 17. Apolipoprotein C-III deficiency accelerates triglyceride hydrolysis by lipoprotein lipase in wild-type and apoE knockout mice.
    Jong MC, Rensen PC, Dahlmans VE, van der Boom H, van Berkel TJ, Havekes LM.
    J Lipid Res; 2001 Oct 24; 42(10):1578-85. PubMed ID: 11590213
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  • 19. Microsomal triacylglycerol transfer protein is required for lumenal accretion of triacylglycerol not associated with ApoB, as well as for ApoB lipidation.
    Kulinski A, Rustaeus S, Vance JE.
    J Biol Chem; 2002 Aug 30; 277(35):31516-25. PubMed ID: 12072432
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  • 20. The assembly and secretion of apolipoprotein B-48-containing very low density lipoproteins in McA-RH7777 cells.
    Stillemark P, Borén J, Andersson M, Larsson T, Rustaeus S, Karlsson KA, Olofsson SO.
    J Biol Chem; 2000 Apr 07; 275(14):10506-13. PubMed ID: 10744742
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