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347 related items for PubMed ID: 21679698

  • 1. Anticancer activity of thymoquinone in breast cancer cells: possible involvement of PPAR-γ pathway.
    Woo CC, Loo SY, Gee V, Yap CW, Sethi G, Kumar AP, Tan KH.
    Biochem Pharmacol; 2011 Sep 01; 82(5):464-75. PubMed ID: 21679698
    [Abstract] [Full Text] [Related]

  • 2. Molecular targeting of Akt by thymoquinone promotes G(1) arrest through translation inhibition of cyclin D1 and induces apoptosis in breast cancer cells.
    Rajput S, Kumar BN, Dey KK, Pal I, Parekh A, Mandal M.
    Life Sci; 2013 Nov 13; 93(21):783-90. PubMed ID: 24044882
    [Abstract] [Full Text] [Related]

  • 3. Thymoquinone from Nigella sativa was more potent than cisplatin in eliminating of SiHa cells via apoptosis with down-regulation of Bcl-2 protein.
    Ng WK, Yazan LS, Ismail M.
    Toxicol In Vitro; 2011 Oct 13; 25(7):1392-8. PubMed ID: 21609759
    [Abstract] [Full Text] [Related]

  • 4. Thymoquinone-induced antitumor and apoptosis in human lung adenocarcinoma cells.
    Samarghandian S, Azimi-Nezhad M, Farkhondeh T.
    J Cell Physiol; 2019 Jul 13; 234(7):10421-10431. PubMed ID: 30387147
    [Abstract] [Full Text] [Related]

  • 5. Thymoquinone up-regulates PTEN expression and induces apoptosis in doxorubicin-resistant human breast cancer cells.
    Arafa el-SA, Zhu Q, Shah ZI, Wani G, Barakat BM, Racoma I, El-Mahdy MA, Wani AA.
    Mutat Res; 2011 Jan 10; 706(1-2):28-35. PubMed ID: 21040738
    [Abstract] [Full Text] [Related]

  • 6. Thymoquinone inhibits tumor growth and induces apoptosis in a breast cancer xenograft mouse model: the role of p38 MAPK and ROS.
    Woo CC, Hsu A, Kumar AP, Sethi G, Tan KH.
    PLoS One; 2013 Jan 10; 8(10):e75356. PubMed ID: 24098377
    [Abstract] [Full Text] [Related]

  • 7. Isorhamnetin inhibits proliferation and invasion and induces apoptosis through the modulation of peroxisome proliferator-activated receptor γ activation pathway in gastric cancer.
    Ramachandran L, Manu KA, Shanmugam MK, Li F, Siveen KS, Vali S, Kapoor S, Abbasi T, Surana R, Smoot DT, Ashktorab H, Tan P, Ahn KS, Yap CW, Kumar AP, Sethi G.
    J Biol Chem; 2012 Nov 02; 287(45):38028-40. PubMed ID: 22992727
    [Abstract] [Full Text] [Related]

  • 8. Targeted apoptotic effects of thymoquinone and tamoxifen on XIAP mediated Akt regulation in breast cancer.
    Rajput S, Kumar BN, Sarkar S, Das S, Azab B, Santhekadur PK, Das SK, Emdad L, Sarkar D, Fisher PB, Mandal M.
    PLoS One; 2013 Nov 02; 8(4):e61342. PubMed ID: 23613836
    [Abstract] [Full Text] [Related]

  • 9. Thymoquinone attenuates phosphorylation of AKT to inhibit kidney cancer cell proliferation.
    Dera A, Rajagopalan P.
    J Food Biochem; 2019 Apr 02; 43(4):e12793. PubMed ID: 31353586
    [Abstract] [Full Text] [Related]

  • 10. Thymoquinone as an anticancer agent: evidence from inhibition of cancer cells viability and invasion in vitro and tumor growth in vivo.
    Attoub S, Sperandio O, Raza H, Arafat K, Al-Salam S, Al Sultan MA, Al Safi M, Takahashi T, Adem A.
    Fundam Clin Pharmacol; 2013 Oct 02; 27(5):557-69. PubMed ID: 22788741
    [Abstract] [Full Text] [Related]

  • 11. Thymoquinone induces apoptosis of human renal carcinoma Caki-1 cells by inhibiting JAK2/STAT3 through pro-oxidant effect.
    Chae IG, Song NY, Kim DH, Lee MY, Park JM, Chun KS.
    Food Chem Toxicol; 2020 May 02; 139():111253. PubMed ID: 32165235
    [Abstract] [Full Text] [Related]

  • 12. Thymoquinone extracted from black seed triggers apoptotic cell death in human colorectal cancer cells via a p53-dependent mechanism.
    Gali-Muhtasib H, Diab-Assaf M, Boltze C, Al-Hmaira J, Hartig R, Roessner A, Schneider-Stock R.
    Int J Oncol; 2004 Oct 02; 25(4):857-66. PubMed ID: 15375533
    [Abstract] [Full Text] [Related]

  • 13. The combination of thymoquinone and paclitaxel shows anti-tumor activity through the interplay with apoptosis network in triple-negative breast cancer.
    Şakalar Ç, İzgi K, İskender B, Sezen S, Aksu H, Çakır M, Kurt B, Turan A, Canatan H.
    Tumour Biol; 2016 Apr 02; 37(4):4467-77. PubMed ID: 26500095
    [Abstract] [Full Text] [Related]

  • 14. Targeting nuclear factor-kappa B activation pathway by thymoquinone: role in suppression of antiapoptotic gene products and enhancement of apoptosis.
    Sethi G, Ahn KS, Aggarwal BB.
    Mol Cancer Res; 2008 Jun 02; 6(6):1059-70. PubMed ID: 18567808
    [Abstract] [Full Text] [Related]

  • 15. Thymoquinone induces apoptosis of human epidermoid carcinoma A431 cells through ROS-mediated suppression of STAT3.
    Park JE, Kim DH, Ha E, Choi SM, Choi JS, Chun KS, Joo SH.
    Chem Biol Interact; 2019 Oct 01; 312():108799. PubMed ID: 31433961
    [Abstract] [Full Text] [Related]

  • 16. Anti-cancer effects of thymoquinone in mouse neuroblastoma (Neuro-2a) cells through caspase-3 activation with down-regulation of XIAP.
    Paramasivam A, Sambantham S, Shabnam J, Raghunandhakumar S, Anandan B, Rajiv R, Vijayashree Priyadharsini J, Jayaraman G.
    Toxicol Lett; 2012 Sep 03; 213(2):151-9. PubMed ID: 22732633
    [Abstract] [Full Text] [Related]

  • 17. Concurrent Reactive Oxygen Species Generation and Aneuploidy Induction Contribute to Thymoquinone Anticancer Activity.
    Al-Hayali M, Garces A, Stocks M, Collins H, Bradshaw TD.
    Molecules; 2021 Aug 25; 26(17):. PubMed ID: 34500570
    [Abstract] [Full Text] [Related]

  • 18. Thymoquinone alleviates nonalcoholic fatty liver disease in rats via suppression of oxidative stress, inflammation, apoptosis.
    Awad AS, Abd Al Haleem EN, El-Bakly WM, Sherief MA.
    Naunyn Schmiedebergs Arch Pharmacol; 2016 Apr 25; 389(4):381-91. PubMed ID: 26753695
    [Abstract] [Full Text] [Related]

  • 19. Anti-cancer properties and mechanisms of action of thymoquinone, the major active ingredient of Nigella sativa.
    Majdalawieh AF, Fayyad MW, Nasrallah GK.
    Crit Rev Food Sci Nutr; 2017 Dec 12; 57(18):3911-3928. PubMed ID: 28140613
    [Abstract] [Full Text] [Related]

  • 20. Thymoquinone induces cell death in human squamous carcinoma cells via caspase activation-dependent apoptosis and LC3-II activation-dependent autophagy.
    Chu SC, Hsieh YS, Yu CC, Lai YY, Chen PN.
    PLoS One; 2014 Dec 12; 9(7):e101579. PubMed ID: 25000169
    [Abstract] [Full Text] [Related]

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