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201 related items for PubMed ID: 21683092

  • 1. Neuroprotective effects of MAPK/ERK1/2 and calpain inhibitors on lactacystin-induced cell damage in primary cortical neurons.
    Jantas D, Lorenc-Koci E, Kubera M, Lason W.
    Neurotoxicology; 2011 Dec; 32(6):845-56. PubMed ID: 21683092
    [Abstract] [Full Text] [Related]

  • 2. Calpain mediates calcium-induced activation of the erk1,2 MAPK pathway and cytoskeletal phosphorylation in neurons: relevance to Alzheimer's disease.
    Veeranna, Kaji T, Boland B, Odrljin T, Mohan P, Basavarajappa BS, Peterhoff C, Cataldo A, Rudnicki A, Amin N, Li BS, Pant HC, Hungund BL, Arancio O, Nixon RA.
    Am J Pathol; 2004 Sep; 165(3):795-805. PubMed ID: 15331404
    [Abstract] [Full Text] [Related]

  • 3. Synergistic induction of apoptosis in human leukemia cells (U937) exposed to bryostatin 1 and the proteasome inhibitor lactacystin involves dysregulation of the PKC/MAPK cascade.
    Vrana JA, Grant S.
    Blood; 2001 Apr 01; 97(7):2105-14. PubMed ID: 11264178
    [Abstract] [Full Text] [Related]

  • 4. Effects of TRH and its analogues on primary cortical neuronal cell damage induced by various excitotoxic, necrotic and apoptotic agents.
    Jantas D, Jaworska-Feil L, Lipkowski AW, Lason W.
    Neuropeptides; 2009 Oct 01; 43(5):371-85. PubMed ID: 19666192
    [Abstract] [Full Text] [Related]

  • 5. Inhibition of the ERK1/2-ubiquitous calpains pathway attenuates experimental pulmonary fibrosis in vivo and in vitro.
    Zou M, Zhang G, Zou J, Liu Y, Liu B, Hu X, Cheng Z.
    Exp Cell Res; 2020 Jun 01; 391(1):111886. PubMed ID: 32017927
    [Abstract] [Full Text] [Related]

  • 6. Atorvastatin prevents Aβ oligomer-induced neurotoxicity in cultured rat hippocampal neurons by inhibiting Tau cleavage.
    Sui HJ, Zhang LL, Liu Z, Jin Y.
    Acta Pharmacol Sin; 2015 May 01; 36(5):553-64. PubMed ID: 25891085
    [Abstract] [Full Text] [Related]

  • 7. Glutamate-induced apoptosis in neuronal cells is mediated via caspase-dependent and independent mechanisms involving calpain and caspase-3 proteases as well as apoptosis inducing factor (AIF) and this process is inhibited by equine estrogens.
    Zhang Y, Bhavnani BR.
    BMC Neurosci; 2006 Jun 15; 7():49. PubMed ID: 16776830
    [Abstract] [Full Text] [Related]

  • 8. Inhibition of extracellular signal-regulated kinases 1/2 provides neuroprotection in spinal cord ischemia/reperfusion injury in rats: relationship with the nuclear factor-kappaB-regulated anti-apoptotic mechanisms.
    Lu K, Liang CL, Liliang PC, Yang CH, Cho CL, Weng HC, Tsai YD, Wang KW, Chen HJ.
    J Neurochem; 2010 Jul 15; 114(1):237-46. PubMed ID: 20403072
    [Abstract] [Full Text] [Related]

  • 9. Calpain- and caspase-mediated alphaII-spectrin and tau proteolysis in rat cerebrocortical neuronal cultures after ecstasy or methamphetamine exposure.
    Warren MW, Zheng W, Kobeissy FH, Cheng Liu M, Hayes RL, Gold MS, Larner SF, Wang KK.
    Int J Neuropsychopharmacol; 2007 Aug 15; 10(4):479-89. PubMed ID: 16882358
    [Abstract] [Full Text] [Related]

  • 10. The ATM kinase inhibitor KU-55933 provides neuroprotection against hydrogen peroxide-induced cell damage via a γH2AX/p-p53/caspase-3-independent mechanism: Inhibition of calpain and cathepsin D.
    Chwastek J, Jantas D, Lasoń W.
    Int J Biochem Cell Biol; 2017 Jun 15; 87():38-53. PubMed ID: 28341201
    [Abstract] [Full Text] [Related]

  • 11. Paeoniflorin ameliorates ischemic neuronal damage in vitro via adenosine A1 receptor-mediated transactivation of epidermal growth factor receptor.
    Zhong M, Song WL, Xu YC, Ye Y, Feng LY.
    Acta Pharmacol Sin; 2015 Mar 15; 36(3):298-310. PubMed ID: 25661317
    [Abstract] [Full Text] [Related]

  • 12. Calpain inhibition protected spinal cord motoneurons against 1-methyl-4-phenylpyridinium ion and rotenone.
    Samantaray S, Knaryan VH, Le Gal C, Ray SK, Banik NL.
    Neuroscience; 2011 Sep 29; 192():263-74. PubMed ID: 21723922
    [Abstract] [Full Text] [Related]

  • 13. Neuroprotective effects of a novel single compound 1-methoxyoctadecan-1-ol isolated from Uncaria sinensis in primary cortical neurons and a photothrombotic ischemia model.
    Jang JY, Choi YW, Kim HN, Kim YR, Hong JW, Bae DW, Park SJ, Shin HK, Choi BT.
    PLoS One; 2014 Sep 29; 9(1):e85322. PubMed ID: 24416390
    [Abstract] [Full Text] [Related]

  • 14. Proteasome inhibition by lactacystin in primary neuronal cells induces both potentially neuroprotective and pro-apoptotic transcriptional responses: a microarray analysis.
    Yew EH, Cheung NS, Choy MS, Qi RZ, Lee AY, Peng ZF, Melendez AJ, Manikandan J, Koay ES, Chiu LL, Ng WL, Whiteman M, Kandiah J, Halliwell B.
    J Neurochem; 2005 Aug 29; 94(4):943-56. PubMed ID: 15992382
    [Abstract] [Full Text] [Related]

  • 15. Cyclin-dependent kinase activity is required for apoptotic death but not inclusion formation in cortical neurons after proteasomal inhibition.
    Rideout HJ, Wang Q, Park DS, Stefanis L.
    J Neurosci; 2003 Feb 15; 23(4):1237-45. PubMed ID: 12598612
    [Abstract] [Full Text] [Related]

  • 16. Evidence that inhibition of p44/42 mitogen-activated protein kinase signaling is a factor in proteasome inhibitor-mediated apoptosis.
    Orlowski RZ, Small GW, Shi YY.
    J Biol Chem; 2002 Aug 02; 277(31):27864-71. PubMed ID: 12023956
    [Abstract] [Full Text] [Related]

  • 17. Calpain-2/p35-p25/Cdk5 pathway is involved in the neuronal apoptosis induced by polybrominated diphenyl ether-153.
    Zhang H, Chang L, Zhang H, Nie J, Zhang Z, Yang X, Vuong AM, Wang Z, Chen A, Niu Q.
    Toxicol Lett; 2017 Aug 05; 277():41-53. PubMed ID: 28559121
    [Abstract] [Full Text] [Related]

  • 18. mu-Calpain activation, DNA fragmentation, and synergistic effects of caspase and calpain inhibitors in protecting hippocampal neurons from ischemic damage.
    Rami A, Agarwal R, Botez G, Winckler J.
    Brain Res; 2000 Jun 02; 866(1-2):299-312. PubMed ID: 10825507
    [Abstract] [Full Text] [Related]

  • 19. Pigment epithelium-derived factor (PEDF) protects cortical neurons in vitro from oxidant injury by activation of extracellular signal-regulated kinase (ERK) 1/2 and induction of Bcl-2.
    Sanchez A, Tripathy D, Yin X, Luo J, Martinez J, Grammas P.
    Neurosci Res; 2012 Jan 02; 72(1):1-8. PubMed ID: 21946416
    [Abstract] [Full Text] [Related]

  • 20. Agonist-induced activation of histamine H3 receptor signals to extracellular signal-regulated kinases 1 and 2 through PKC-, PLD-, and EGFR-dependent mechanisms.
    Lai X, Ye L, Liao Y, Jin L, Ma Q, Lu B, Sun Y, Shi Y, Zhou N.
    J Neurochem; 2016 Apr 02; 137(2):200-15. PubMed ID: 26826667
    [Abstract] [Full Text] [Related]

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