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182 related items for PubMed ID: 21684798
1. Natural product drug discovery: the successful optimization of ISP-1 and halichondrin B. Yeung BK. Curr Opin Chem Biol; 2011 Aug; 15(4):523-8. PubMed ID: 21684798 [Abstract] [Full Text] [Related]
2. Fingolimod (FTY720): a recently approved multiple sclerosis drug based on a fungal secondary metabolite. Strader CR, Pearce CJ, Oberlies NH. J Nat Prod; 2011 Apr 25; 74(4):900-7. PubMed ID: 21456524 [Abstract] [Full Text] [Related]
3. Macrocyclic ketone analogues of halichondrin B. Zheng W, Seletsky BM, Palme MH, Lydon PJ, Singer LA, Chase CE, Lemelin CA, Shen Y, Davis H, Tremblay L, Towle MJ, Salvato KA, Wels BF, Aalfs KK, Kishi Y, Littlefield BA, Yu MJ. Bioorg Med Chem Lett; 2004 Nov 15; 14(22):5551-4. PubMed ID: 15482922 [Abstract] [Full Text] [Related]
5. Discovery of fingolimod, the sphingosine 1-phosphate receptor modulator and its application for the therapy of multiple sclerosis. Chiba K, Adachi K. Future Med Chem; 2012 Apr 02; 4(6):771-81. PubMed ID: 22530640 [Abstract] [Full Text] [Related]
11. In vitro and in vivo anticancer activities of synthetic macrocyclic ketone analogues of halichondrin B. Towle MJ, Salvato KA, Budrow J, Wels BF, Kuznetsov G, Aalfs KK, Welsh S, Zheng W, Seletsky BM, Palme MH, Habgood GJ, Singer LA, Dipietro LV, Wang Y, Chen JJ, Quincy DA, Davis A, Yoshimatsu K, Kishi Y, Yu MJ, Littlefield BA. Cancer Res; 2001 Feb 01; 61(3):1013-21. PubMed ID: 11221827 [Abstract] [Full Text] [Related]
12. Immunomodulatory Effects of Halichondrin Isolated from Marine Sponges and Its Synthetic Analogs in Oncological Applications. Dissanayake DS, Nagahawatta DP, Lee JS, Jeon YJ. Mar Drugs; 2024 Sep 20; 22(9):. PubMed ID: 39330307 [Abstract] [Full Text] [Related]
16. Developing natural product drugs: Supply problems and how they have been overcome. Newman DJ. Pharmacol Ther; 2016 Jun 20; 162():1-9. PubMed ID: 26706239 [Abstract] [Full Text] [Related]
17. Synthesis of natural products containing spiroketals via intramolecular hydrogen abstraction. Sperry J, Liu YC, Brimble MA. Org Biomol Chem; 2010 Jan 07; 8(1):29-38. PubMed ID: 20024126 [Abstract] [Full Text] [Related]