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Journal Abstract Search

468 related items for PubMed ID: 21685937

  • 1. SPARC functions as an anti-stress factor by inactivating p53 through Akt-mediated MDM2 phosphorylation to promote melanoma cell survival.
    Fenouille N, Puissant A, Tichet M, Zimniak G, Abbe P, Mallavialle A, Rocchi S, Ortonne JP, Deckert M, Ballotti R, Tartare-Deckert S.
    Oncogene; 2011 Dec 08; 30(49):4887-900. PubMed ID: 21685937
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  • 2. The epithelial-mesenchymal transition (EMT) regulatory factor SLUG (SNAI2) is a downstream target of SPARC and AKT in promoting melanoma cell invasion.
    Fenouille N, Tichet M, Dufies M, Pottier A, Mogha A, Soo JK, Rocchi S, Mallavialle A, Galibert MD, Khammari A, Lacour JP, Ballotti R, Deckert M, Tartare-Deckert S.
    PLoS One; 2012 Dec 08; 7(7):e40378. PubMed ID: 22911700
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  • 3. Secreted protein acidic and rich in cysteine antagonizes bufalin-induced apoptosis in gastric cancer cells.
    Li A, Qu X, Li Z, Qu J, Song N, Ma Y, Liu Y.
    Mol Med Rep; 2015 Aug 08; 12(2):2926-32. PubMed ID: 25936899
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  • 4. The p53/p21Cip1/ Waf1 pathway mediates the effects of SPARC on melanoma cell cycle progression.
    Fenouille N, Robert G, Tichet M, Puissant A, Dufies M, Rocchi S, Ortonne JP, Deckert M, Ballotti R, Tartare-Deckert S.
    Pigment Cell Melanoma Res; 2011 Feb 08; 24(1):219-32. PubMed ID: 20955243
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  • 12. Knockdown of secreted protein acidic and rich in cysteine (SPARC) expression diminishes radiosensitivity of glioma cells.
    Liu H, Zhang H, Jiang X, Ma Y, Xu Y, Feng S, Liu F.
    Cancer Biother Radiopharm; 2011 Dec 08; 26(6):705-15. PubMed ID: 22145659
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  • 14. Human oncoprotein MDM2 activates the Akt signaling pathway through an interaction with the repressor element-1 silencing transcription factor conferring a survival advantage to cancer cells.
    Singh S, Ramamoorthy M, Vaughan C, Yeudall WA, Deb S, Palit Deb S.
    Cell Death Differ; 2013 Apr 08; 20(4):558-66. PubMed ID: 23238568
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  • 15. Helicobacter pylori Infection Activates the Akt-Mdm2-p53 Signaling Pathway in Gastric Epithelial Cells.
    Shu X, Yang Z, Li ZH, Chen L, Zhou XD, Xie Y, Lu NH.
    Dig Dis Sci; 2015 Apr 08; 60(4):876-86. PubMed ID: 25480405
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  • 18. A novel BH3 mimetic reveals a mitogen-activated protein kinase-dependent mechanism of melanoma cell death controlled by p53 and reactive oxygen species.
    Verhaegen M, Bauer JA, Martín de la Vega C, Wang G, Wolter KG, Brenner JC, Nikolovska-Coleska Z, Bengtson A, Nair R, Elder JT, Van Brocklin M, Carey TE, Bradford CR, Wang S, Soengas MS.
    Cancer Res; 2006 Dec 01; 66(23):11348-59. PubMed ID: 17145881
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  • 20. Persistent activation of the Fyn/ERK kinase signaling axis mediates imatinib resistance in chronic myelogenous leukemia cells through upregulation of intracellular SPARC.
    Fenouille N, Puissant A, Dufies M, Robert G, Jacquel A, Ohanna M, Deckert M, Pasquet JM, Mahon FX, Cassuto JP, Raynaud S, Tartare-Deckert S, Auberger P.
    Cancer Res; 2010 Dec 01; 70(23):9659-70. PubMed ID: 21098700
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