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424 related items for PubMed ID: 21694768

  • 1. Small molecule amiloride modulates oncogenic RNA alternative splicing to devitalize human cancer cells.
    Chang JG, Yang DM, Chang WH, Chow LP, Chan WL, Lin HH, Huang HD, Chang YS, Hung CH, Yang WK.
    PLoS One; 2011; 6(6):e18643. PubMed ID: 21694768
    [Abstract] [Full Text] [Related]

  • 2. Alternative splicing in human cancer cells is modulated by the amiloride derivative 3,5-diamino-6-chloro-N-(N-(2,6-dichlorobenzoyl)carbamimidoyl)pyrazine-2-carboxide.
    Lee CC, Chang WH, Chang YS, Yang JM, Chang CS, Hsu KC, Chen YT, Liu TY, Chen YC, Lin SY, Wu YC, Chang JG.
    Mol Oncol; 2019 Aug; 13(8):1744-1762. PubMed ID: 31152681
    [Abstract] [Full Text] [Related]

  • 3. Amiloride modulates alternative splicing in leukemic cells and resensitizes Bcr-AblT315I mutant cells to imatinib.
    Chang WH, Liu TC, Yang WK, Lee CC, Lin YH, Chen TY, Chang JG.
    Cancer Res; 2011 Jan 15; 71(2):383-92. PubMed ID: 21224352
    [Abstract] [Full Text] [Related]

  • 4. Modulating roles of amiloride in irradiation-induced antiproliferative effects in glioblastoma multiforme cells involving Akt phosphorylation and the alternative splicing of apoptotic genes.
    Tang JY, Chang HW, Chang JG.
    DNA Cell Biol; 2013 Sep 15; 32(9):504-10. PubMed ID: 23822711
    [Abstract] [Full Text] [Related]

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  • 7. Hepatocyte growth factor enhances alternative splicing of the Kruppel-like factor 6 (KLF6) tumor suppressor to promote growth through SRSF1.
    Muñoz Ú, Puche JE, Hannivoort R, Lang UE, Cohen-Naftaly M, Friedman SL.
    Mol Cancer Res; 2012 Sep 15; 10(9):1216-27. PubMed ID: 22859706
    [Abstract] [Full Text] [Related]

  • 8. Akt2 regulation of Cdc2-like kinases (Clk/Sty), serine/arginine-rich (SR) protein phosphorylation, and insulin-induced alternative splicing of PKCbetaII messenger ribonucleic acid.
    Jiang K, Patel NA, Watson JE, Apostolatos H, Kleiman E, Hanson O, Hagiwara M, Cooper DR.
    Endocrinology; 2009 May 15; 150(5):2087-97. PubMed ID: 19116344
    [Abstract] [Full Text] [Related]

  • 9. The RNA-binding protein Sam68 modulates the alternative splicing of Bcl-x.
    Paronetto MP, Achsel T, Massiello A, Chalfant CE, Sette C.
    J Cell Biol; 2007 Mar 26; 176(7):929-39. PubMed ID: 17371836
    [Abstract] [Full Text] [Related]

  • 10. The CD44 alternative v9 exon contains a splicing enhancer responsive to the SR proteins 9G8, ASF/SF2, and SRp20.
    Galiana-Arnoux D, Lejeune F, Gesnel MC, Stevenin J, Breathnach R, Del Gatto-Konczak F.
    J Biol Chem; 2003 Aug 29; 278(35):32943-53. PubMed ID: 12826680
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  • 12. Exonic splicing enhancer-dependent selection of the bovine papillomavirus type 1 nucleotide 3225 3' splice site can be rescued in a cell lacking splicing factor ASF/SF2 through activation of the phosphatidylinositol 3-kinase/Akt pathway.
    Liu X, Mayeda A, Tao M, Zheng ZM.
    J Virol; 2003 Feb 29; 77(3):2105-15. PubMed ID: 12525645
    [Abstract] [Full Text] [Related]

  • 13. The splicing factor SRp20 modifies splicing of its own mRNA and ASF/SF2 antagonizes this regulation.
    Jumaa H, Nielsen PJ.
    EMBO J; 1997 Aug 15; 16(16):5077-85. PubMed ID: 9305649
    [Abstract] [Full Text] [Related]

  • 14. Specific inhibition of serine- and arginine-rich splicing factors phosphorylation, spliceosome assembly, and splicing by the antitumor drug NB-506.
    Pilch B, Allemand E, Facompré M, Bailly C, Riou JF, Soret J, Tazi J.
    Cancer Res; 2001 Sep 15; 61(18):6876-84. PubMed ID: 11559564
    [Abstract] [Full Text] [Related]

  • 15. Alternative splicing of iodothyronine deiodinases in pituitary adenomas. Regulation by oncoprotein SF2/ASF.
    Piekielko-Witkowska A, Kedzierska H, Poplawski P, Wojcicka A, Rybicka B, Maksymowicz M, Grajkowska W, Matyja E, Mandat T, Bonicki W, Nauman P.
    Biochim Biophys Acta; 2013 Jun 15; 1832(6):763-72. PubMed ID: 23462647
    [Abstract] [Full Text] [Related]

  • 16. Cell motility is controlled by SF2/ASF through alternative splicing of the Ron protooncogene.
    Ghigna C, Giordano S, Shen H, Benvenuto F, Castiglioni F, Comoglio PM, Green MR, Riva S, Biamonti G.
    Mol Cell; 2005 Dec 22; 20(6):881-90. PubMed ID: 16364913
    [Abstract] [Full Text] [Related]

  • 17. The gene encoding the splicing factor SF2/ASF is a proto-oncogene.
    Karni R, de Stanchina E, Lowe SW, Sinha R, Mu D, Krainer AR.
    Nat Struct Mol Biol; 2007 Mar 22; 14(3):185-93. PubMed ID: 17310252
    [Abstract] [Full Text] [Related]

  • 18. Protein Sam68 regulates the alternative splicing of survivin DEx3.
    Gaytan-Cervantes J, Gonzalez-Torres C, Maldonado V, Zampedri C, Ceballos-Cancino G, Melendez-Zajgla J.
    J Biol Chem; 2017 Aug 18; 292(33):13745-13757. PubMed ID: 28655776
    [Abstract] [Full Text] [Related]

  • 19. Poly(ADP-ribose) binds to the splicing factor ASF/SF2 and regulates its phosphorylation by DNA topoisomerase I.
    Malanga M, Czubaty A, Girstun A, Staron K, Althaus FR.
    J Biol Chem; 2008 Jul 18; 283(29):19991-8. PubMed ID: 18495665
    [Abstract] [Full Text] [Related]

  • 20. Alternative splicing of caspase 9 is modulated by the phosphoinositide 3-kinase/Akt pathway via phosphorylation of SRp30a.
    Shultz JC, Goehe RW, Wijesinghe DS, Murudkar C, Hawkins AJ, Shay JW, Minna JD, Chalfant CE.
    Cancer Res; 2010 Nov 15; 70(22):9185-96. PubMed ID: 21045158
    [Abstract] [Full Text] [Related]

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