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348 related items for PubMed ID: 2169942

  • 1. The effect of putative protein kinase C inhibitors, K252a and staurosporine, on the human neutrophil respiratory burst activated by both receptor stimulation and post-receptor mechanisms.
    Twomey B, Muid RE, Dale MM.
    Br J Pharmacol; 1990 Aug; 100(4):819-25. PubMed ID: 2169942
    [Abstract] [Full Text] [Related]

  • 2. Staurosporine and its derivatives enhance f-Met-Leu-Phe-induced superoxide production via phospholipase D activation in human polymorphonuclear leukocytes.
    Mori T, Ando M, Takagi K.
    Int J Clin Pharmacol Ther; 1994 Aug; 32(8):422-8. PubMed ID: 7981927
    [Abstract] [Full Text] [Related]

  • 3. Protein kinase C activity is not involved in N-formylmethionyl-leucyl-phenylalanine-induced phospholipase D activation in human neutrophils, but is essential for concomitant NADPH oxidase activation: studies with a staurosporine analogue with improved selectivity for protein kinase C.
    Kessels GC, Krause KH, Verhoeven AJ.
    Biochem J; 1993 Jun 15; 292 ( Pt 3)(Pt 3):781-5. PubMed ID: 8391255
    [Abstract] [Full Text] [Related]

  • 4. The effect of new potent selective inhibitors of protein kinase C on the neutrophil respiratory burst.
    Twomey B, Muid RE, Nixon JS, Sedgwick AD, Wilkinson SE, Dale MM.
    Biochem Biophys Res Commun; 1990 Sep 28; 171(3):1087-92. PubMed ID: 2171506
    [Abstract] [Full Text] [Related]

  • 5. Utility of staurosporine in uncovering differences in the signal transduction pathways for superoxide production in neutrophils.
    Robinson JM, Heyworth PG, Badwey JA.
    Biochim Biophys Acta; 1990 Oct 15; 1055(1):55-62. PubMed ID: 2171676
    [Abstract] [Full Text] [Related]

  • 6. The protein kinase C inhibitor, K252a, inhibits superoxide production in human neutrophils activated by both PIP2-dependent and -independent mechanisms.
    Twomey BM, Clay K, Dale MM.
    Biochem Pharmacol; 1991 May 15; 41(10):1449-54. PubMed ID: 1850276
    [Abstract] [Full Text] [Related]

  • 7. Activation of the respiratory burst and tyrosine phosphorylation of proteins in human neutrophils: no direct relationship and involvement of protein kinase C-dependent and -independent signaling pathways.
    Azuma EK, Kitagawa S, Yuo A, Mizoguchi H, Umezawa K, Takaku F, Saito M.
    Biochim Biophys Acta; 1993 Nov 07; 1179(2):213-23. PubMed ID: 8218364
    [Abstract] [Full Text] [Related]

  • 8. Studies of signal transduction in the respiratory burst-associated stimulation of fMet-Leu-Phe-induced tubulin tyrosinolation and phorbol 12-myristate 13-acetate-induced posttranslational incorporation of tyrosine into multiple proteins in activated neutrophils and HL-60 cells.
    Nath J, Powledge A, Wright DG.
    J Biol Chem; 1989 Jan 15; 264(2):848-55. PubMed ID: 2536026
    [Abstract] [Full Text] [Related]

  • 9. A comparison of the priming effect of phorbol myristate acetate and phorbol dibutyrate on fMet-Leu-Phe-induced oxidative burst in human neutrophils.
    Gaudry M, Combadiere C, Marquetty C, Hakim J.
    Immunopharmacology; 1990 Jan 15; 20(1):45-56. PubMed ID: 2172183
    [Abstract] [Full Text] [Related]

  • 10. Modulation of TNF-alpha-priming and stimulation-dependent superoxide generation in human neutrophils by protein kinase inhibitors.
    Utsumi T, Klostergaard J, Akimaru K, Edashige K, Sato EF, Utsumi K.
    Arch Biochem Biophys; 1992 Apr 15; 294(1):271-8. PubMed ID: 1312809
    [Abstract] [Full Text] [Related]

  • 11. Superoxide production by human eosinophils can be inhibited in an agonist-selective manner.
    Bach MK, Brashler JR, Petzold EN, Sanders ME.
    Agents Actions; 1992 Jan 15; 35(1-2):1-11. PubMed ID: 1324597
    [Abstract] [Full Text] [Related]

  • 12. Effect of staurosporine on fMet-Leu-Phe-stimulated human neutrophils: dissociated release of inositol 1,4,5-trisphosphate, diacylglycerol and intracellular calcium.
    Nigam S, Müller S, Walzog B.
    Biochim Biophys Acta; 1992 Jun 29; 1135(3):301-8. PubMed ID: 1320409
    [Abstract] [Full Text] [Related]

  • 13. Staurosporine inhibits the respiratory burst and induces exocytosis in human neutrophils.
    Dewald B, Thelen M, Wymann MP, Baggiolini M.
    Biochem J; 1989 Dec 15; 264(3):879-84. PubMed ID: 2559721
    [Abstract] [Full Text] [Related]

  • 14. Selective inhibition of protein kinase C, mitogen-activated protein kinase, and neutrophil activation in response to calcium pyrophosphate dihydrate crystals, formyl-methionyl-leucyl-phenylalanine, and phorbol ester by O-(chloroacetyl-carbamoyl) fumagillol (AGM-1470; TNP-470).
    Tudan C, Jackson JK, Pelech SL, Attardo G, Burt H.
    Biochem Pharmacol; 1999 Dec 15; 58(12):1869-80. PubMed ID: 10591141
    [Abstract] [Full Text] [Related]

  • 15. Neutrophil priming by granulocyte colony stimulating factor and its modulation by protein kinase inhibitors.
    Tanimura M, Kobuchi H, Utsumi T, Yoshioka T, Kataoka S, Fujita Y, Utsumi K.
    Biochem Pharmacol; 1992 Sep 25; 44(6):1045-52. PubMed ID: 1384497
    [Abstract] [Full Text] [Related]

  • 16. Stimulation of the human neutrophil respiratory burst by formyl peptides is primed by a protein kinase inhibitor, staurosporine.
    Combadière C, el Benna J, Pedruzzi E, Hakim J, Périanin A.
    Blood; 1993 Nov 01; 82(9):2890-8. PubMed ID: 8219237
    [Abstract] [Full Text] [Related]

  • 17. Involvement of calcium in modulation of neutrophil function by phorbol esters that activate protein kinase C isotypes and related enzymes.
    Merritt JE, Moores KE, Evans AT, Sharma P, Evans FJ, MacPhee CH.
    Biochem J; 1993 Feb 01; 289 ( Pt 3)(Pt 3):919-26. PubMed ID: 8435086
    [Abstract] [Full Text] [Related]

  • 18. 1,2-dioctanoyl-sn-glycerol can stimulate neutrophils by different mechanisms. Evidence for a pathway that does not involve phosphorylation of the 47-kDa protein.
    Badwey JA, Robinson JM, Heyworth PG, Curnutte JT.
    J Biol Chem; 1989 Dec 05; 264(34):20676-82. PubMed ID: 2555367
    [Abstract] [Full Text] [Related]

  • 19. Signal transduction in N-formyl-methionyl-leucyl-phenylalanine and concanavalin A stimulated human neutrophils: superoxide production without a rise in intracellular free calcium.
    Liang SL, Woodlock TJ, Whitin JC, Lichtman MA, Segel GB.
    J Cell Physiol; 1990 Nov 05; 145(2):295-302. PubMed ID: 2174064
    [Abstract] [Full Text] [Related]

  • 20. Superoxide generation by guinea-pig peritoneal macrophages is inhibited by rolipram, staurosporine and mepacrine in an agonist-dependent manner.
    Turner NC, Wood LJ.
    Cell Signal; 1994 Nov 05; 6(8):923-31. PubMed ID: 7718411
    [Abstract] [Full Text] [Related]

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