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Journal Abstract Search


209 related items for PubMed ID: 21715330

  • 1. Incomplete folding upon binding mediates Cdk4/cyclin D complex activation by tyrosine phosphorylation of inhibitor p27 protein.
    Ou L, Ferreira AM, Otieno S, Xiao L, Bashford D, Kriwacki RW.
    J Biol Chem; 2011 Aug 26; 286(34):30142-51. PubMed ID: 21715330
    [Abstract] [Full Text] [Related]

  • 2. Phosphorylation of p27Kip1 regulates assembly and activation of cyclin D1-Cdk4.
    Larrea MD, Liang J, Da Silva T, Hong F, Shao SH, Han K, Dumont D, Slingerland JM.
    Mol Cell Biol; 2008 Oct 26; 28(20):6462-72. PubMed ID: 18710949
    [Abstract] [Full Text] [Related]

  • 3. The role of the LH subdomain in the function of the Cip/Kip cyclin-dependent kinase regulators.
    Otieno S, Grace CR, Kriwacki RW.
    Biophys J; 2011 May 18; 100(10):2486-94. PubMed ID: 21575583
    [Abstract] [Full Text] [Related]

  • 4. Differential modification of p27Kip1 controls its cyclin D-cdk4 inhibitory activity.
    James MK, Ray A, Leznova D, Blain SW.
    Mol Cell Biol; 2008 Jan 18; 28(1):498-510. PubMed ID: 17908796
    [Abstract] [Full Text] [Related]

  • 5. p27Kip1 inhibits cyclin D-cyclin-dependent kinase 4 by two independent modes.
    Ray A, James MK, Larochelle S, Fisher RP, Blain SW.
    Mol Cell Biol; 2009 Feb 18; 29(4):986-99. PubMed ID: 19075005
    [Abstract] [Full Text] [Related]

  • 6. Cell cycle exit during terminal erythroid differentiation is associated with accumulation of p27(Kip1) and inactivation of cdk2 kinase.
    Hsieh FF, Barnett LA, Green WF, Freedman K, Matushansky I, Skoultchi AI, Kelley LL.
    Blood; 2000 Oct 15; 96(8):2746-54. PubMed ID: 11023508
    [Abstract] [Full Text] [Related]

  • 7. p27Kip1 and p21Cip1 collaborate in the regulation of transcription by recruiting cyclin-Cdk complexes on the promoters of target genes.
    Orlando S, Gallastegui E, Besson A, Abril G, Aligué R, Pujol MJ, Bachs O.
    Nucleic Acids Res; 2015 Aug 18; 43(14):6860-73. PubMed ID: 26071952
    [Abstract] [Full Text] [Related]

  • 8. Psoriatic epidermis is associated with upregulation of CDK2 and inhibition of CDK4 activity.
    Henri P, Prevel C, Pellerano M, Lacotte J, Stoebner PE, Morris MC, Meunier L.
    Br J Dermatol; 2020 Mar 18; 182(3):678-689. PubMed ID: 31145809
    [Abstract] [Full Text] [Related]

  • 9. Differential interaction of the cyclin-dependent kinase (Cdk) inhibitor p27Kip1 with cyclin A-Cdk2 and cyclin D2-Cdk4.
    Blain SW, Montalvo E, Massagué J.
    J Biol Chem; 1997 Oct 10; 272(41):25863-72. PubMed ID: 9325318
    [Abstract] [Full Text] [Related]

  • 10. Structural and functional analysis of cyclin D1 reveals p27 and substrate inhibitor binding requirements.
    Liu S, Bolger JK, Kirkland LO, Premnath PN, McInnes C.
    ACS Chem Biol; 2010 Dec 17; 5(12):1169-82. PubMed ID: 20843055
    [Abstract] [Full Text] [Related]

  • 11. Mechanism of cell cycle entry mediated by the intrinsically disordered protein p27(Kip1).
    Ou L, Waddell MB, Kriwacki RW.
    ACS Chem Biol; 2012 Apr 20; 7(4):678-82. PubMed ID: 22276948
    [Abstract] [Full Text] [Related]

  • 12. Brk/Protein tyrosine kinase 6 phosphorylates p27KIP1, regulating the activity of cyclin D-cyclin-dependent kinase 4.
    Patel P, Asbach B, Shteyn E, Gomez C, Coltoff A, Bhuyan S, Tyner AL, Wagner R, Blain SW.
    Mol Cell Biol; 2015 May 20; 35(9):1506-22. PubMed ID: 25733683
    [Abstract] [Full Text] [Related]

  • 13. p27kip1 Regulates cdk2 activity in the proliferating zone of the mouse intestinal epithelium: potential role in neoplasia.
    Smartt HJ, Guilmeau S, Nasser SV, Nicholas C, Bancroft L, Simpson SA, Yeh N, Yang W, Mariadason JM, Koff A, Augenlicht LH.
    Gastroenterology; 2007 Jul 20; 133(1):232-43. PubMed ID: 17631145
    [Abstract] [Full Text] [Related]

  • 14. Clinical CDK4/6 inhibitors induce selective and immediate dissociation of p21 from cyclin D-CDK4 to inhibit CDK2.
    Pack LR, Daigh LH, Chung M, Meyer T.
    Nat Commun; 2021 Jun 07; 12(1):3356. PubMed ID: 34099663
    [Abstract] [Full Text] [Related]

  • 15. Transforming growth factor beta(1) selectively inhibits the cyclic AMP-dependent proliferation of primary thyroid epithelial cells by preventing the association of cyclin D3-cdk4 with nuclear p27(kip1).
    Depoortere F, Pirson I, Bartek J, Dumont JE, Roger PP.
    Mol Biol Cell; 2000 Mar 07; 11(3):1061-76. PubMed ID: 10712520
    [Abstract] [Full Text] [Related]

  • 16. Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta.
    Reynisdóttir I, Polyak K, Iavarone A, Massagué J.
    Genes Dev; 1995 Aug 01; 9(15):1831-45. PubMed ID: 7649471
    [Abstract] [Full Text] [Related]

  • 17. Lineage specific composition of cyclin D-CDK4/CDK6-p27 complexes reveals distinct functions of CDK4, CDK6 and individual D-type cyclins in differentiating cells of embryonic origin.
    Bryja V, Pacherník J, Vondráček J, Souček K, Čajánek L, Horvath V, Holubcová Z, Dvořák P, Hampl A.
    Cell Prolif; 2008 Dec 01; 41(6):875-893. PubMed ID: 19040567
    [Abstract] [Full Text] [Related]

  • 18. Regulated activating Thr172 phosphorylation of cyclin-dependent kinase 4(CDK4): its relationship with cyclins and CDK "inhibitors".
    Bockstaele L, Kooken H, Libert F, Paternot S, Dumont JE, de Launoit Y, Roger PP, Coulonval K.
    Mol Cell Biol; 2006 Jul 01; 26(13):5070-85. PubMed ID: 16782892
    [Abstract] [Full Text] [Related]

  • 19. Removal of Cdk inhibitors through both sequestration and downregulation in zearalenone-treated MCF-7 breast cancer cells.
    Ahamed S, Foster JS, Bukovsky A, Diehl JA, Wimalasena J.
    Mol Carcinog; 2002 May 01; 34(1):45-58. PubMed ID: 12112322
    [Abstract] [Full Text] [Related]

  • 20. p27 allosterically activates cyclin-dependent kinase 4 and antagonizes palbociclib inhibition.
    Guiley KZ, Stevenson JW, Lou K, Barkovich KJ, Kumarasamy V, Wijeratne TU, Bunch KL, Tripathi S, Knudsen ES, Witkiewicz AK, Shokat KM, Rubin SM.
    Science; 2019 Dec 13; 366(6471):. PubMed ID: 31831640
    [Abstract] [Full Text] [Related]


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