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3. Effect of polyamine depletion by alpha-difluoromethylornithine or (2R,5R)-6-heptyne-2,5-diamine on drug-induced topoisomerase II-mediated DNA cleavage and cytotoxicity in human and murine leukemia cells. Bakic M, Chan D, Freireich EJ, Marton LJ, Zwelling LA. Cancer Res; 1987 Dec 15; 47(24 Pt 1):6437-43. PubMed ID: 2824033 [Abstract] [Full Text] [Related]
4. Retinoic acid and phorbol ester induced hyperphosphorylation of topoisomerase II-alpha is an early event in HL-60 human leukaemia cell differentiation: effect on topoisomerase activity and etoposide sensitivity. Chresta CM, Hall BF, Francis GE. Leukemia; 1995 Aug 15; 9(8):1373-81. PubMed ID: 7643627 [Abstract] [Full Text] [Related]
5. Phorbol regulation of topoisomerases I and II in human leukemia cells. Studies in an additional cell pair sensitive or resistant to phorbol-induced differentiation. Ellis AL, Altschuler E, Bales E, Hinds M, Mayes J, Soares L, Zipf TF, Zwelling LA. Biochem Pharmacol; 1994 Jan 20; 47(2):387-96. PubMed ID: 8304982 [Abstract] [Full Text] [Related]
6. Effect of retinoic acid on DNA cleavage and cytotoxicity of topoisomerase II-reactive drugs in a human head and neck squamous carcinoma cell line. Kim HK, Zwelling LA, Sacks PG, Hong WK, Chan D, Silberman L, Glisson BS. Cancer Res; 1989 Mar 01; 49(5):1197-201. PubMed ID: 2537145 [Abstract] [Full Text] [Related]
7. Multidrug resistance-associated protein gene overexpression and reduced drug sensitivity of topoisomerase II in a human breast carcinoma MCF7 cell line selected for etoposide resistance. Schneider E, Horton JK, Yang CH, Nakagawa M, Cowan KH. Cancer Res; 1994 Jan 01; 54(1):152-8. PubMed ID: 7903202 [Abstract] [Full Text] [Related]
8. Antagonistic effect of aclarubicin on the cytotoxicity of etoposide and 4'-(9-acridinylamino)methanesulfon-m-anisidide in human small cell lung cancer cell lines and on topoisomerase II-mediated DNA cleavage. Jensen PB, Sørensen BS, Demant EJ, Sehested M, Jensen PS, Vindeløv L, Hansen HH. Cancer Res; 1990 Jun 01; 50(11):3311-6. PubMed ID: 2159380 [Abstract] [Full Text] [Related]
9. Topoisomerase II as a target of VM-26 and 4'-(9-acridinylamino)methanesulfon-m-aniside in atypical multidrug resistant human small cell lung carcinoma cells. de Jong S, Kooistra AJ, de Vries EG, Mulder NH, Zijlstra JG. Cancer Res; 1993 Mar 01; 53(5):1064-71. PubMed ID: 8382551 [Abstract] [Full Text] [Related]
10. Alterations in the topoisomerase II alpha gene, messenger RNA, and subcellular protein distribution as well as reduced expression of the DNA topoisomerase II beta enzyme in a mitoxantrone-resistant HL-60 human leukemia cell line. Harker WG, Slade DL, Parr RL, Feldhoff PW, Sullivan DM, Holguin MH. Cancer Res; 1995 Apr 15; 55(8):1707-16. PubMed ID: 7712479 [Abstract] [Full Text] [Related]
11. Resistance to etoposide in human leukemia HL-60 cells: reduction in drug-induced DNA cleavage associated with hypophosphorylation of topoisomerase II phosphopeptides. Ganapathi R, Constantinou A, Kamath N, Dubyak G, Grabowski D, Krivacic K. Mol Pharmacol; 1996 Aug 15; 50(2):243-8. PubMed ID: 8700130 [Abstract] [Full Text] [Related]
12. Relative activity of structural analogues of amsacrine against human leukemia cell lines containing amsacrine-sensitive or -resistant forms of topoisomerase II: use of computer simulations in new drug development. Zwelling LA, Mitchell MJ, Satitpunwaycha P, Mayes J, Altschuler E, Hinds M, Baguley BC. Cancer Res; 1992 Jan 01; 52(1):209-17. PubMed ID: 1309224 [Abstract] [Full Text] [Related]
13. Differential induction of etoposide-mediated apoptosis in human leukemia HL-60 and K562 cells. Ritke MK, Rusnak JM, Lazo JS, Allan WP, Dive C, Heer S, Yalowich JC. Mol Pharmacol; 1994 Oct 01; 46(4):605-11. PubMed ID: 7969039 [Abstract] [Full Text] [Related]
14. Altered DNA topoisomerase II activity in Chinese hamster cells resistant to topoisomerase II inhibitors. Pommier Y, Kerrigan D, Schwartz RE, Swack JA, McCurdy A. Cancer Res; 1986 Jun 01; 46(6):3075-81. PubMed ID: 3009009 [Abstract] [Full Text] [Related]
15. Modulation of 4'-(9-acridinylamino)methanesulfon-m-anisidide-induced, topoisomerase II-mediated DNA cleavage by gossypol. Adlakha RC, Ashorn CL, Chan D, Zwelling LA. Cancer Res; 1989 Apr 15; 49(8):2052-8. PubMed ID: 2539251 [Abstract] [Full Text] [Related]
16. Altered regulation of c-myc in an HL-60 differentiation resistant subclone, HL-60-1E3. Ely CM, Leftwich JA, Chenevix-Trench G, Hall RE, Westin EH. Cancer Res; 1987 Sep 01; 47(17):4595-600. PubMed ID: 3476196 [Abstract] [Full Text] [Related]
17. Relationship between topoisomerase II level and chemosensitivity in human tumor cell lines. Fry AM, Chresta CM, Davies SM, Walker MC, Harris AL, Hartley JA, Masters JR, Hickson ID. Cancer Res; 1991 Dec 15; 51(24):6592-5. PubMed ID: 1660343 [Abstract] [Full Text] [Related]
18. Topoisomerase II-mediated DNA damage produced by 4'-(9-acridinylamino)methanesulfon-m-anisidide and related acridines in L1210 cells and isolated nuclei: relation to cytotoxicity. Covey JM, Kohn KW, Kerrigan D, Tilchen EJ, Pommier Y. Cancer Res; 1988 Feb 15; 48(4):860-5. PubMed ID: 2827887 [Abstract] [Full Text] [Related]
19. Novobiocin- and phorbol-12-myristate-13-acetate-induced differentiation of human leukemia cells associated with a reduction in topoisomerase II activity. Constantinou A, Henning-Chubb C, Huberman E. Cancer Res; 1989 Mar 01; 49(5):1110-7. PubMed ID: 2537141 [Abstract] [Full Text] [Related]
20. Attenuated topoisomerase II content directly correlates with a low level of drug resistance in a Chinese hamster ovary cell line. Webb CD, Latham MD, Lock RB, Sullivan DM. Cancer Res; 1991 Dec 15; 51(24):6543-9. PubMed ID: 1660341 [Abstract] [Full Text] [Related] Page: [Next] [New Search]