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Journal Abstract Search


139 related items for PubMed ID: 21724838

  • 1. Long-acting pegylated human GH in children with GH deficiency: a single-dose, dose-escalation trial investigating safety, tolerability, pharmacokinetics and pharmacodynamics.
    de Schepper J, Rasmussen MH, Gucev Z, Eliakim A, Battelino T.
    Eur J Endocrinol; 2011 Sep; 165(3):401-9. PubMed ID: 21724838
    [Abstract] [Full Text] [Related]

  • 2. Pegylated long-acting human growth hormone possesses a promising once-weekly treatment profile, and multiple dosing is well tolerated in adult patients with growth hormone deficiency.
    Søndergaard E, Klose M, Hansen M, Hansen BS, Andersen M, Feldt-Rasmussen U, Laursen T, Rasmussen MH, Christiansen JS.
    J Clin Endocrinol Metab; 2011 Mar; 96(3):681-8. PubMed ID: 21177789
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  • 3. Pegylated long-acting human growth hormone is well-tolerated in healthy subjects and possesses a potential once-weekly pharmacokinetic and pharmacodynamic treatment profile.
    Rasmussen MH, Bysted BV, Anderson TW, Klitgaard T, Madsen J.
    J Clin Endocrinol Metab; 2010 Jul; 95(7):3411-7. PubMed ID: 20427496
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  • 4. Somapacitan, a once-weekly reversible albumin-binding GH derivative, in children with GH deficiency: A randomized dose-escalation trial.
    Battelino T, Rasmussen MH, De Schepper J, Zuckerman-Levin N, Gucev Z, Sävendahl L, NN8640-4042 Study Group.
    Clin Endocrinol (Oxf); 2017 Oct; 87(4):350-358. PubMed ID: 28656605
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  • 5. Multiple doses of pegylated long-acting growth hormone are well tolerated in healthy male volunteers and possess a potential once-weekly treatment profile.
    Rasmussen MH, Jensen L, Anderson TW, Klitgaard T, Madsen J.
    Clin Endocrinol (Oxf); 2010 Dec; 73(6):769-76. PubMed ID: 20718773
    [Abstract] [Full Text] [Related]

  • 6. Comparative pharmacokinetics and pharmacodynamics of a PEGylated recombinant human growth hormone and daily recombinant human growth hormone in growth hormone-deficient children.
    Hou L, Chen ZH, Liu D, Cheng YG, Luo XP.
    Drug Des Devel Ther; 2016 Dec; 10():13-21. PubMed ID: 26719670
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  • 7. Reversible Albumin-Binding GH Possesses a Potential Once-Weekly Treatment Profile in Adult Growth Hormone Deficiency.
    Rasmussen MH, Janukonyté J, Klose M, Marina D, Tanvig M, Nielsen LF, Höybye C, Andersen M, Feldt-Rasmussen U, Christiansen JS.
    J Clin Endocrinol Metab; 2016 Mar; 101(3):988-98. PubMed ID: 26727076
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  • 10. A reversible albumin-binding growth hormone derivative is well tolerated and possesses a potential once-weekly treatment profile.
    Rasmussen MH, Olsen MW, Alifrangis L, Klim S, Suntum M.
    J Clin Endocrinol Metab; 2014 Oct; 99(10):E1819-29. PubMed ID: 25013997
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  • 11. Long-Acting C-Terminal Peptide-Modified hGH (MOD-4023): Results of a Safety and Dose-Finding Study in GHD Children.
    Zelinska N, Iotova V, Skorodok J, Malievsky O, Peterkova V, Samsonova L, Rosenfeld RG, Zadik Z, Jaron-Mendelson M, Koren R, Amitzi L, Raduk D, Hershkovitz O, Hart G.
    J Clin Endocrinol Metab; 2017 May 01; 102(5):1578-1587. PubMed ID: 28323965
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  • 12. MOD-4023, a long-acting carboxy-terminal peptide-modified human growth hormone: results of a Phase 2 study in growth hormone-deficient adults.
    Strasburger CJ, Vanuga P, Payer J, Pfeifer M, Popovic V, Bajnok L, Góth M, Olšovská V, Trejbalová L, Vadasz J, Fima E, Koren R, Amitzi L, Bidlingmaier M, Hershkovitz O, Hart G, Biller BMK.
    Eur J Endocrinol; 2017 Mar 01; 176(3):283-294. PubMed ID: 27932411
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  • 13. Three weekly injections (TWI) of low-dose growth hormone (GH) restore low normal circulating IGF-I concentrations and reverse cardiac abnormalities associated with adult onset GH deficiency (GHD).
    Pincelli AI, Bragato R, Scacchi M, Branzi G, Osculati G, Viarengo R, Leonetti G, Cavagnini F.
    J Endocrinol Invest; 2003 May 01; 26(5):420-8. PubMed ID: 12906369
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  • 14. IGF-I and IGF binding protein-3 levels during initial GH dosage step-up are indicators of GH sensitivity in GH-deficient children and short children born small for gestational age.
    Ranke MB, Traunecker R, Martin DD, Schweizer R, Schwarze CP, Wollmann HA, Binder G.
    Horm Res; 2005 May 01; 64(2):68-76. PubMed ID: 16113581
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  • 15. Pharmacokinetics and Pharmacodynamics of Once-Weekly Somapacitan in Children and Adults: Supporting Dosing Rationales with a Model-Based Analysis of Three Phase I Trials.
    Juul RV, Rasmussen MH, Agersø H, Overgaard RV.
    Clin Pharmacokinet; 2019 Jan 01; 58(1):63-75. PubMed ID: 29671202
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  • 17. Once-Weekly Somapacitan vs Daily GH in Children With GH Deficiency: Results From a Randomized Phase 2 Trial.
    Sävendahl L, Battelino T, Brod M, Højby Rasmussen M, Horikawa R, Juul RV, Saenger P, REAL 3 study group.
    J Clin Endocrinol Metab; 2020 Apr 01; 105(4):e1847-61. PubMed ID: 31917835
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  • 19. Lipoatrophy in GH deficient patients treated with a long-acting pegylated GH.
    Touraine P, D'Souza GA, Kourides I, Abs R, Barclay P, Xie R, Pico A, Torres-Vela E, Ekman B, GH Lipoatrophy Study Group.
    Eur J Endocrinol; 2009 Oct 01; 161(4):533-40. PubMed ID: 19654233
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  • 20. The absorption profile and availability of a physiological subcutaneously administered dose of recombinant human growth hormone (GH) in adults with GH deficiency.
    Janssen YJ, Frölich M, Roelfsema F.
    Br J Clin Pharmacol; 1999 Mar 01; 47(3):273-8. PubMed ID: 10215751
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