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Journal Abstract Search


166 related items for PubMed ID: 21726170

  • 1. In vitro metabolism of nobiletin, a polymethoxy-flavonoid, by human liver microsomes and cytochrome P450.
    Koga N, Ohta C, Kato Y, Haraguchi K, Endo T, Ogawa K, Ohta H, Yano M.
    Xenobiotica; 2011 Nov; 41(11):927-33. PubMed ID: 21726170
    [Abstract] [Full Text] [Related]

  • 2. Comparative study on nobiletin metabolism with liver microsomes from rats, Guinea pigs and hamsters and rat cytochrome p450.
    Koga N, Matsuo M, Ohta C, Haraguchi K, Matsuoka M, Kato Y, Ishii T, Yano M, Ohta H.
    Biol Pharm Bull; 2007 Dec; 30(12):2317-23. PubMed ID: 18057719
    [Abstract] [Full Text] [Related]

  • 3. Identification of human cytochrome P450 isozymes responsible for the in vitro oxidative metabolism of finasteride.
    Huskey SW, Dean DC, Miller RR, Rasmusson GH, Chiu SH.
    Drug Metab Dispos; 1995 Oct; 23(10):1126-35. PubMed ID: 8654202
    [Abstract] [Full Text] [Related]

  • 4. Ropivacaine, a new amide-type local anesthetic agent, is metabolized by cytochromes P450 1A and 3A in human liver microsomes.
    Ekström G, Gunnarsson UB.
    Drug Metab Dispos; 1996 Sep; 24(9):955-61. PubMed ID: 8886604
    [Abstract] [Full Text] [Related]

  • 5. Orphenadrine and methimazole inhibit multiple cytochrome P450 enzymes in human liver microsomes.
    Guo Z, Raeissi S, White RB, Stevens JC.
    Drug Metab Dispos; 1997 Mar; 25(3):390-3. PubMed ID: 9172960
    [Abstract] [Full Text] [Related]

  • 6. The metabolism of the piperazine-type phenothiazine neuroleptic perazine by the human cytochrome P-450 isoenzymes.
    Wójcikowski J, Pichard-Garcia L, Maurel P, Daniel WA.
    Eur Neuropsychopharmacol; 2004 May; 14(3):199-208. PubMed ID: 15056479
    [Abstract] [Full Text] [Related]

  • 7. Identification of the human P-450 enzymes responsible for the sulfoxidation and thiono-oxidation of diethyldithiocarbamate methyl ester: role of P-450 enzymes in disulfiram bioactivation.
    Madan A, Parkinson A, Faiman MD.
    Alcohol Clin Exp Res; 1998 Sep; 22(6):1212-9. PubMed ID: 9756035
    [Abstract] [Full Text] [Related]

  • 8. Identification of human cytochrome P450 and flavin-containing monooxygenase enzymes involved in the metabolism of lorcaserin, a novel selective human 5-hydroxytryptamine 2C agonist.
    Usmani KA, Chen WG, Sadeque AJ.
    Drug Metab Dispos; 2012 Apr; 40(4):761-71. PubMed ID: 22266842
    [Abstract] [Full Text] [Related]

  • 9. In vitro metabolism of simvastatin in humans [SBT]identification of metabolizing enzymes and effect of the drug on hepatic P450s.
    Prueksaritanont T, Gorham LM, Ma B, Liu L, Yu X, Zhao JJ, Slaughter DE, Arison BH, Vyas KP.
    Drug Metab Dispos; 1997 Oct; 25(10):1191-9. PubMed ID: 9321523
    [Abstract] [Full Text] [Related]

  • 10. Characterization of metabolites and human P450 isoforms involved in the microsomal metabolism of mesaconitine.
    Ye L, Tang L, Gong Y, Lv C, Zheng Z, Jiang Z, Liu Z.
    Xenobiotica; 2011 Jan; 41(1):46-58. PubMed ID: 21105783
    [Abstract] [Full Text] [Related]

  • 11. In vitro characterization of the metabolism of haloperidol using recombinant cytochrome p450 enzymes and human liver microsomes.
    Fang J, McKay G, Song J, Remillrd A, Li X, Midha K.
    Drug Metab Dispos; 2001 Dec; 29(12):1638-43. PubMed ID: 11717183
    [Abstract] [Full Text] [Related]

  • 12. Metabolic activation of dacarbazine by human cytochromes P450: the role of CYP1A1, CYP1A2, and CYP2E1.
    Reid JM, Kuffel MJ, Miller JK, Rios R, Ames MM.
    Clin Cancer Res; 1999 Aug; 5(8):2192-7. PubMed ID: 10473105
    [Abstract] [Full Text] [Related]

  • 13. Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A.
    Niwa T, Shiraga T, Mitani Y, Terakawa M, Tokuma Y, Kagayama A.
    Drug Metab Dispos; 2000 Sep; 28(9):1128-34. PubMed ID: 10950860
    [Abstract] [Full Text] [Related]

  • 14. Characterization of human cytochrome P450 enzymes involved in the metabolism of cyamemazine.
    Arbus C, Benyamina A, Llorca PM, Baylé F, Bromet N, Massiere F, Garay RP, Hameg A.
    Eur J Pharm Sci; 2007 Dec; 32(4-5):357-66. PubMed ID: 17951033
    [Abstract] [Full Text] [Related]

  • 15. Oxidative metabolism of 5-methoxy-N,N-diisopropyltryptamine (Foxy) by human liver microsomes and recombinant cytochrome P450 enzymes.
    Narimatsu S, Yonemoto R, Saito K, Takaya K, Kumamoto T, Ishikawa T, Asanuma M, Funada M, Kiryu K, Naito S, Yoshida Y, Yamamoto S, Hanioka N.
    Biochem Pharmacol; 2006 Apr 28; 71(9):1377-85. PubMed ID: 16510126
    [Abstract] [Full Text] [Related]

  • 16. Reevaluation of the microsomal metabolism of montelukast: major contribution by CYP2C8 at clinically relevant concentrations.
    Filppula AM, Laitila J, Neuvonen PJ, Backman JT.
    Drug Metab Dispos; 2011 May 28; 39(5):904-11. PubMed ID: 21289076
    [Abstract] [Full Text] [Related]

  • 17. Identification of the human liver cytochrome P450 isoenzyme responsible for the 6-methylhydroxylation of the novel anticancer drug 5,6-dimethylxanthenone-4-acetic acid.
    Zhou S, Paxton JW, Tingle MD, Kestell P.
    Drug Metab Dispos; 2000 Dec 28; 28(12):1449-56. PubMed ID: 11095582
    [Abstract] [Full Text] [Related]

  • 18. Inhibition of cytochrome P450 enzymes involved in ketamine metabolism by use of liver microsomes and specific cytochrome P450 enzymes from horses, dogs, and humans.
    Mössner LD, Schmitz A, Theurillat R, Thormann W, Mevissen M.
    Am J Vet Res; 2011 Nov 28; 72(11):1505-13. PubMed ID: 22023129
    [Abstract] [Full Text] [Related]

  • 19. Identification of the human liver cytochrome P450 isoenzymes responsible for the 5-methylhydroxylation of the novel anti-fibrotic drug AKF-PD.
    He X, Luo X, Liu Z, Hu G, Cheng Z.
    Xenobiotica; 2011 Oct 28; 41(10):844-50. PubMed ID: 21679010
    [Abstract] [Full Text] [Related]

  • 20. Human cytochrome P450-catalyzed conversion of the proestrogenic pesticide methoxychlor into an estrogen. Role of CYP2C19 and CYP1A2 in O-demethylation.
    Stresser DM, Kupfer D.
    Drug Metab Dispos; 1998 Sep 28; 26(9):868-74. PubMed ID: 9733665
    [Abstract] [Full Text] [Related]


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