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Journal Abstract Search

290 related items for PubMed ID: 21730132

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  • 5. A mouse p53 mutant lacking the proline-rich domain rescues Mdm4 deficiency and provides insight into the Mdm2-Mdm4-p53 regulatory network.
    Toledo F, Krummel KA, Lee CJ, Liu CW, Rodewald LW, Tang M, Wahl GM.
    Cancer Cell; 2006 Apr; 9(4):273-85. PubMed ID: 16616333
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  • 6. Synergistic roles of Mdm2 and Mdm4 for p53 inhibition in central nervous system development.
    Xiong S, Van Pelt CS, Elizondo-Fraire AC, Liu G, Lozano G.
    Proc Natl Acad Sci U S A; 2006 Feb 28; 103(9):3226-31. PubMed ID: 16492743
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  • 7. Widespread overexpression of epitope-tagged Mdm4 does not accelerate tumor formation in vivo.
    De Clercq S, Gembarska A, Denecker G, Maetens M, Naessens M, Haigh K, Haigh JJ, Marine JC.
    Mol Cell Biol; 2010 Nov 28; 30(22):5394-405. PubMed ID: 20855528
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  • 8. Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53.
    Parant J, Chavez-Reyes A, Little NA, Yan W, Reinke V, Jochemsen AG, Lozano G.
    Nat Genet; 2001 Sep 28; 29(1):92-5. PubMed ID: 11528400
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  • 9. MDM4 enhances p53 stability by promoting an active conformation of the protein upon DNA damage.
    Di Conza G, Mancini F, Buttarelli M, Pontecorvi A, Trimarchi F, Moretti F.
    Cell Cycle; 2012 Feb 15; 11(4):749-60. PubMed ID: 22374672
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  • 10. Distinct roles of Mdm2 and Mdm4 in red cell production.
    Maetens M, Doumont G, Clercq SD, Francoz S, Froment P, Bellefroid E, Klingmuller U, Lozano G, Marine JC.
    Blood; 2007 Mar 15; 109(6):2630-3. PubMed ID: 17105817
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  • 12. The MDM4/MDM2-p53-IGF1 axis controls axonal regeneration, sprouting and functional recovery after CNS injury.
    Joshi Y, Sória MG, Quadrato G, Inak G, Zhou L, Hervera A, Rathore KI, Elnaggar M, Cucchiarini M, Marine JC, Puttagunta R, Di Giovanni S.
    Brain; 2015 Jul 15; 138(Pt 7):1843-62. PubMed ID: 25981963
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  • 13. MDM2 E3 ligase activity is essential for p53 regulation and cell cycle integrity.
    Chinnam M, Xu C, Lama R, Zhang X, Cedeno CD, Wang Y, Stablewski AB, Goodrich DW, Wang X.
    PLoS Genet; 2022 May 15; 18(5):e1010171. PubMed ID: 35588102
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  • 15. MDMX Recruits UbcH5c to Facilitate MDM2 E3 Ligase Activity and Subsequent p53 Degradation In Vivo.
    Yang J, Jin A, Han J, Chen X, Zheng J, Zhang Y.
    Cancer Res; 2021 Feb 15; 81(4):898-909. PubMed ID: 33277368
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  • 18. Dissecting the p53-Mdm2 feedback loop in vivo: uncoupling the role in p53 stability and activity.
    Pant V, Lozano G.
    Oncotarget; 2014 Mar 15; 5(5):1149-56. PubMed ID: 24658419
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  • 19. Regulation of p53 by Mdm2 E3 ligase function is dispensable in embryogenesis and development, but essential in response to DNA damage.
    Tollini LA, Jin A, Park J, Zhang Y.
    Cancer Cell; 2014 Aug 11; 26(2):235-47. PubMed ID: 25117711
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  • 20. Dual Targeting of MDM4 and FTH1 by MMRi71 for Induced Protein Degradation and p53-Independent Apoptosis in Leukemia Cells.
    Lama R, Galster SL, Xu C, Davison LW, Chemler SR, Wang X.
    Molecules; 2022 Nov 08; 27(22):. PubMed ID: 36431769
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