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257 related items for PubMed ID: 21733335

  • 1. Mitogen-activated protein kinase mediates the apoptosis of highly metastatic human non-small cell lung cancer cells induced by isothiocyanates.
    Yan H, Zhu Y, Liu B, Wu H, Li Y, Wu X, Zhou Q, Xu K.
    Br J Nutr; 2011 Dec; 106(12):1779-91. PubMed ID: 21733335
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  • 2. Inhibition of benzo(a)pyrene-induced lung tumorigenesis in A/J mice by dietary N-acetylcysteine conjugates of benzyl and phenethyl isothiocyanates during the postinitiation phase is associated with activation of mitogen-activated protein kinases and p53 activity and induction of apoptosis.
    Yang YM, Conaway CC, Chiao JW, Wang CX, Amin S, Whysner J, Dai W, Reinhardt J, Chung FL.
    Cancer Res; 2002 Jan 01; 62(1):2-7. PubMed ID: 11782348
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  • 3. Apoptosis induced by benzyl isothiocyanate in gefitinib-resistant lung cancer cells is associated with Akt/MAPK pathways and generation of reactive oxygen species.
    Liu BN, Yan HQ, Wu X, Pan ZH, Zhu Y, Meng ZW, Zhou QH, Xu K.
    Cell Biochem Biophys; 2013 May 01; 66(1):81-92. PubMed ID: 23111983
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  • 10. Sustained activation of ERK and Cdk2/cyclin-A signaling pathway by pemetrexed leading to S-phase arrest and apoptosis in human non-small cell lung cancer A549 cells.
    Yang TY, Chang GC, Chen KC, Hung HW, Hsu KH, Sheu GT, Hsu SL.
    Eur J Pharmacol; 2011 Aug 01; 663(1-3):17-26. PubMed ID: 21575631
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  • 11. Flavokawain B induces apoptosis of non-small cell lung cancer H460 cells via Bax-initiated mitochondrial and JNK pathway.
    An J, Gao Y, Wang J, Zhu Q, Ma Y, Wu J, Sun J, Tang Y.
    Biotechnol Lett; 2012 Oct 01; 34(10):1781-8. PubMed ID: 22729748
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  • 12. Benzyl isothiocyanate (BITC) inhibits migration and invasion of human colon cancer HT29 cells by inhibiting matrix metalloproteinase-2/-9 and urokinase plasminogen (uPA) through PKC and MAPK signaling pathway.
    Lai KC, Huang AC, Hsu SC, Kuo CL, Yang JS, Wu SH, Chung JG.
    J Agric Food Chem; 2010 Mar 10; 58(5):2935-42. PubMed ID: 20136087
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  • 13. Effects of antioxidants and caspase-3 inhibitor on the phenylethyl isothiocyanate-induced apoptotic signaling pathways in human PLC/PRF/5 cells.
    Wu SJ, Ng LT, Lin CC.
    Eur J Pharmacol; 2005 Aug 22; 518(2-3):96-106. PubMed ID: 16054126
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  • 14. Oxidation-triggered c-Jun N-terminal kinase (JNK) and p38 mitogen-activated protein (MAP) kinase pathways for apoptosis in human leukaemic cells stimulated by epigallocatechin-3-gallate (EGCG): a distinct pathway from those of chemically induced and receptor-mediated apoptosis.
    Saeki K, Kobayashi N, Inazawa Y, Zhang H, Nishitoh H, Ichijo H, Saeki K, Isemura M, Yuo A.
    Biochem J; 2002 Dec 15; 368(Pt 3):705-20. PubMed ID: 12206715
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  • 15. Ingestion of an isothiocyanate metabolite from cruciferous vegetables inhibits growth of human prostate cancer cell xenografts by apoptosis and cell cycle arrest.
    Chiao JW, Wu H, Ramaswamy G, Conaway CC, Chung FL, Wang L, Liu D.
    Carcinogenesis; 2004 Aug 15; 25(8):1403-8. PubMed ID: 15016658
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  • 16. Indomethacin induces apoptosis in 786-O renal cell carcinoma cells by activating mitogen-activated protein kinases and AKT.
    Ou YC, Yang CR, Cheng CL, Raung SL, Hung YY, Chen CJ.
    Eur J Pharmacol; 2007 Jun 01; 563(1-3):49-60. PubMed ID: 17341418
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  • 17. EGCG inhibits the invasion of highly invasive CL1-5 lung cancer cells through suppressing MMP-2 expression via JNK signaling and induces G2/M arrest.
    Deng YT, Lin JK.
    J Agric Food Chem; 2011 Dec 28; 59(24):13318-27. PubMed ID: 22082235
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  • 18. Isoobtusilactone A induces cell cycle arrest and apoptosis through reactive oxygen species/apoptosis signal-regulating kinase 1 signaling pathway in human breast cancer cells.
    Kuo PL, Chen CY, Hsu YL.
    Cancer Res; 2007 Aug 01; 67(15):7406-20. PubMed ID: 17671211
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  • 20. Activation of nonsteroidal anti-inflammatory drug-activated gene-1 via extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase revealed a isochaihulactone-triggered apoptotic pathway in human lung cancer A549 cells.
    Chen YL, Lin PC, Chen SP, Lin CC, Tsai NM, Cheng YL, Chang WL, Lin SZ, Harn HJ.
    J Pharmacol Exp Ther; 2007 Nov 01; 323(2):746-56. PubMed ID: 17715378
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