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82 related items for PubMed ID: 21735455

  • 1. Geraniol and simvastatin show a synergistic effect on a human hepatocarcinoma cell line.
    Polo MP, Crespo R, de Bravo MG.
    Cell Biochem Funct; 2011 Aug; 29(6):452-8. PubMed ID: 21735455
    [Abstract] [Full Text] [Related]

  • 2. Effect of geraniol on fatty-acid and mevalonate metabolism in the human hepatoma cell line Hep G2.
    Polo MP, de Bravo MG.
    Biochem Cell Biol; 2006 Feb; 84(1):102-11. PubMed ID: 16462894
    [Abstract] [Full Text] [Related]

  • 3. Simvastatin modulates the adhesion and growth of hepatocellular carcinoma cells via decrease of integrin expression and ROCK.
    Relja B, Meder F, Wang M, Blaheta R, Henrich D, Marzi I, Lehnert M.
    Int J Oncol; 2011 Mar; 38(3):879-85. PubMed ID: 21206971
    [Abstract] [Full Text] [Related]

  • 4. Transcriptional and posttranscriptional inhibition of HMGCR and PC biosynthesis by geraniol in 2 Hep-G2 cell proliferation linked pathways.
    Crespo R, Montero Villegas S, Abba MC, de Bravo MG, Polo MP.
    Biochem Cell Biol; 2013 Jun; 91(3):131-9. PubMed ID: 23668785
    [Abstract] [Full Text] [Related]

  • 5. Synergistic antiproliferative and anticholesterogenic effects of linalool, 1,8-cineole, and simvastatin on human cell lines.
    Rodenak Kladniew B, Polo M, Montero Villegas S, Galle M, Crespo R, García de Bravo M.
    Chem Biol Interact; 2014 May 05; 214():57-68. PubMed ID: 24613879
    [Abstract] [Full Text] [Related]

  • 6. HMG-CoA reductase inhibitor simvastatin overcomes bortezomib-induced apoptosis resistance by disrupting a geranylgeranyl pyrophosphate-dependent survival pathway.
    Fuchs D, Berges C, Opelz G, Daniel V, Naujokat C.
    Biochem Biophys Res Commun; 2008 Sep 19; 374(2):309-14. PubMed ID: 18625202
    [Abstract] [Full Text] [Related]

  • 7. [Inhibition of proliferation and induction of apoptosis by simvastatin in K562 leukemic cell line].
    Ren H, Zhang N, Xu H, Lu D.
    Zhonghua Xue Ye Xue Za Zhi; 2001 Feb 19; 22(2):72-5. PubMed ID: 11877052
    [Abstract] [Full Text] [Related]

  • 8. Clarification of the pleiotropic effects of statins on mevalonate pathway and the feedback regulation of isoprenoids requires more comprehensive investigation.
    Bianco AM, Zanin V, Marcuzzi A, Crovella S.
    Cell Biochem Funct; 2012 Mar 19; 30(2):176. PubMed ID: 22275121
    [No Abstract] [Full Text] [Related]

  • 9. [Effects of simvastatin on the proliferation of HepG2 cells].
    Liu W, Zhang LF, Zhang YH.
    Zhonghua Gan Zang Bing Za Zhi; 2010 Oct 19; 18(10):751-3. PubMed ID: 21059291
    [Abstract] [Full Text] [Related]

  • 10. Simvastatin induces growth inhibition and apoptosis in HepG2 and Huh7 hepatocellular carcinoma cells via upregulation of Notch1 expression.
    Huang X, Ma J, Xu J, Su Q, Zhao J.
    Mol Med Rep; 2015 Mar 19; 11(3):2334-40. PubMed ID: 25412322
    [Abstract] [Full Text] [Related]

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  • 12. Effects of simvastatin, acetylsalicylic acid, and rosiglitazone on proliferation of normal and cancerous prostate epithelial cells at therapeutic concentrations.
    Murtola TJ, Pennanen P, Syvälä H, Bläuer M, Ylikomi T, Tammela TL.
    Prostate; 2009 Jun 15; 69(9):1017-23. PubMed ID: 19301305
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  • 14. Simvastatin inhibits the proliferation of human prostate cancer PC-3 cells via down-regulation of the insulin-like growth factor 1 receptor.
    Sekine Y, Furuya Y, Nishii M, Koike H, Matsui H, Suzuki K.
    Biochem Biophys Res Commun; 2008 Jul 25; 372(2):356-61. PubMed ID: 18489904
    [Abstract] [Full Text] [Related]

  • 15. Simvastatin inhibits growth via apoptosis and the induction of cell cycle arrest in human melanoma cells.
    Saito A, Saito N, Mol W, Furukawa H, Tsutsumida A, Oyama A, Sekido M, Sasaki S, Yamamoto Y.
    Melanoma Res; 2008 Apr 25; 18(2):85-94. PubMed ID: 18337644
    [Abstract] [Full Text] [Related]

  • 16. Simvastatin elicits dilation of isolated porcine retinal arterioles: role of nitric oxide and mevalonate-rho kinase pathways.
    Nagaoka T, Hein TW, Yoshida A, Kuo L.
    Invest Ophthalmol Vis Sci; 2007 Feb 25; 48(2):825-32. PubMed ID: 17251484
    [Abstract] [Full Text] [Related]

  • 17. Simvastatin suppresses self-renewal of mouse embryonic stem cells by inhibiting RhoA geranylgeranylation.
    Lee MH, Cho YS, Han YM.
    Stem Cells; 2007 Jul 25; 25(7):1654-63. PubMed ID: 17464088
    [Abstract] [Full Text] [Related]

  • 18. Effect of ethanol on cell growth and cholesterol metabolism in cultured Hep G2 cells.
    Polo MP, de Bravo MG, de Alaniz MJ.
    Biochem Cell Biol; 2003 Dec 25; 81(6):379-86. PubMed ID: 14663504
    [Abstract] [Full Text] [Related]

  • 19. Anticancer efficacy of simvastatin on prostate cancer cells and tumor xenografts is associated with inhibition of Akt and reduced prostate-specific antigen expression.
    Kochuparambil ST, Al-Husein B, Goc A, Soliman S, Somanath PR.
    J Pharmacol Exp Ther; 2011 Feb 25; 336(2):496-505. PubMed ID: 21059805
    [Abstract] [Full Text] [Related]

  • 20. Comparative effects of high and low-dose simvastatin on prostate epithelial cells: the role of LDL.
    Murtola TJ, Syvälä H, Pennanen P, Bläuer M, Solakivi T, Ylikomi T, Tammela TL.
    Eur J Pharmacol; 2011 Dec 30; 673(1-3):96-100. PubMed ID: 22040920
    [Abstract] [Full Text] [Related]

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