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Journal Abstract Search


188 related items for PubMed ID: 2173698

  • 1. Further localization of binding sites for thrombin and protein C in human thrombomodulin.
    Hayashi T, Zushi M, Yamamoto S, Suzuki K.
    J Biol Chem; 1990 Nov 25; 265(33):20156-9. PubMed ID: 2173698
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  • 3. Monoclonal antibodies for human thrombomodulin which recognize binding sites for thrombin and protein C.
    Hayashi T, Suzuki K.
    J Biochem; 1990 Nov 25; 108(5):874-8. PubMed ID: 1964460
    [Abstract] [Full Text] [Related]

  • 4. The function of calcium in protein C activation by thrombin and the thrombin-thrombomodulin complex can be distinguished by mutational analysis of protein C derivatives.
    Rezaie AR, Esmon CT.
    J Biol Chem; 1992 Dec 25; 267(36):26104-9. PubMed ID: 1334492
    [Abstract] [Full Text] [Related]

  • 5. The last three consecutive epidermal growth factor-like structures of human thrombomodulin comprise the minimum functional domain for protein C-activating cofactor activity and anticoagulant activity.
    Zushi M, Gomi K, Yamamoto S, Maruyama I, Hayashi T, Suzuki K.
    J Biol Chem; 1989 Jun 25; 264(18):10351-3. PubMed ID: 2543666
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  • 7. Sequences required for thrombomodulin cofactor activity within the fourth epidermal growth factor-like domain of human thrombomodulin.
    Lentz SR, Chen Y, Sadler JE.
    J Biol Chem; 1993 Jul 15; 268(20):15312-7. PubMed ID: 8392074
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  • 8. Monoclonal antibodies against human thrombomodulin whose epitope is located in epidermal growth factor-like domains.
    Nawa K, Ono M, Fujiwara H, Sugiyama N, Uchiyama T, Marumoto Y.
    Biochim Biophys Acta; 1994 Apr 13; 1205(2):162-70. PubMed ID: 7512385
    [Abstract] [Full Text] [Related]

  • 9. Microthrombomodulin. Residues 310-486 from the epidermal growth factor precursor homology domain of thrombomodulin will accelerate protein C activation.
    Stearns DJ, Kurosawa S, Esmon CT.
    J Biol Chem; 1989 Feb 25; 264(6):3352-6. PubMed ID: 2536746
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  • 10. The fifth and sixth growth factor-like domains of thrombomodulin bind to the anion-binding exosite of thrombin and alter its specificity.
    Ye J, Liu LW, Esmon CT, Johnson AE.
    J Biol Chem; 1992 Jun 05; 267(16):11023-8. PubMed ID: 1317850
    [Abstract] [Full Text] [Related]

  • 11. Alanine-scanning mutagenesis of the epidermal growth factor-like domains of human thrombomodulin identifies critical residues for its cofactor activity.
    Nagashima M, Lundh E, Leonard JC, Morser J, Parkinson JF.
    J Biol Chem; 1993 Feb 05; 268(4):2888-92. PubMed ID: 8381415
    [Abstract] [Full Text] [Related]

  • 12. A 10-kDa cyanogen bromide fragment from the epidermal growth factor homology domain of rabbit thrombomodulin contains the primary thrombin binding site.
    Kurosawa S, Stearns DJ, Jackson KW, Esmon CT.
    J Biol Chem; 1988 May 05; 263(13):5993-6. PubMed ID: 2834358
    [Abstract] [Full Text] [Related]

  • 13. A domain composed of epidermal growth factor-like structures of human thrombomodulin is essential for thrombin binding and for protein C activation.
    Suzuki K, Hayashi T, Nishioka J, Kosaka Y, Zushi M, Honda G, Yamamoto S.
    J Biol Chem; 1989 Mar 25; 264(9):4872-6. PubMed ID: 2538465
    [Abstract] [Full Text] [Related]

  • 14. Thrombin inhibition by cyclic peptides from thrombomodulin.
    Lougheed JC, Bowman CL, Meininger DP, Komives EA.
    Protein Sci; 1995 Apr 25; 4(4):773-80. PubMed ID: 7613475
    [Abstract] [Full Text] [Related]

  • 15. Activation of thrombin-activable fibrinolysis inhibitor requires epidermal growth factor-like domain 3 of thrombomodulin and is inhibited competitively by protein C.
    Kokame K, Zheng X, Sadler JE.
    J Biol Chem; 1998 May 15; 273(20):12135-9. PubMed ID: 9575159
    [Abstract] [Full Text] [Related]

  • 16. Interference of blood-coagulation vitamin K-dependent proteins in the activation of human protein C. Involvement of the 4-carboxyglutamic acid domain in two distinct interactions with the thrombin-thrombomodulin complex and with phospholipids.
    Freyssinet JM, Beretz A, Klein-Soyer C, Gauchy J, Schuhler S, Cazenave JP.
    Biochem J; 1988 Dec 01; 256(2):501-7. PubMed ID: 2851994
    [Abstract] [Full Text] [Related]

  • 17. The active site of thrombin is altered upon binding to thrombomodulin. Two distinct structural changes are detected by fluorescence, but only one correlates with protein C activation.
    Ye J, Esmon NL, Esmon CT, Johnson AE.
    J Biol Chem; 1991 Dec 05; 266(34):23016-21. PubMed ID: 1660464
    [Abstract] [Full Text] [Related]

  • 18. The effect of phospholipids on the activation of protein C by the human thrombin-thrombomodulin complex.
    Freyssinet JM, Gauchy J, Cazenave JP.
    Biochem J; 1986 Aug 15; 238(1):151-7. PubMed ID: 3026338
    [Abstract] [Full Text] [Related]

  • 19. Tryptophans 231 and 234 in protein C report the Ca(2+)-dependent conformational change required for activation by the thrombin-thrombomodulin complex.
    Rezaie AR, Esmon CT.
    Biochemistry; 1995 Sep 26; 34(38):12221-6. PubMed ID: 7547963
    [Abstract] [Full Text] [Related]

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