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Journal Abstract Search

219 related items for PubMed ID: 21745194

  • 1. cAMP signalling protects proximal tubular epithelial cells from cisplatin-induced apoptosis via activation of Epac.
    Qin Y, Stokman G, Yan K, Ramaiahgari S, Verbeek F, de Graauw M, van de Water B, Price LS.
    Br J Pharmacol; 2012 Feb; 165(4b):1137-50. PubMed ID: 21745194
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  • 2. Epac-Rap signaling reduces oxidative stress in the tubular epithelium.
    Stokman G, Qin Y, Booij TH, Ramaiahgari S, Lacombe M, Dolman ME, van Dorenmalen KM, Teske GJ, Florquin S, Schwede F, van de Water B, Kok RJ, Price LS.
    J Am Soc Nephrol; 2014 Jul; 25(7):1474-85. PubMed ID: 24511123
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  • 6. PKA and Epac cooperate to augment bradykinin-induced interleukin-8 release from human airway smooth muscle cells.
    Roscioni SS, Kistemaker LE, Menzen MH, Elzinga CR, Gosens R, Halayko AJ, Meurs H, Schmidt M.
    Respir Res; 2009 Sep 29; 10(1):88. PubMed ID: 19788733
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  • 8. EPAC activation inhibits acetaldehyde-induced activation and proliferation of hepatic stellate cell via Rap1.
    Yang Y, Yang F, Wu X, Lv X, Li J.
    Can J Physiol Pharmacol; 2016 May 29; 94(5):498-507. PubMed ID: 26854595
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  • 9. PDE4 inhibitor, roflumilast protects cardiomyocytes against NO-induced apoptosis via activation of PKA and Epac dual pathways.
    Kwak HJ, Park KM, Choi HE, Chung KS, Lim HJ, Park HY.
    Cell Signal; 2008 May 29; 20(5):803-14. PubMed ID: 18276108
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  • 10. Low nociceptor GRK2 prolongs prostaglandin E2 hyperalgesia via biased cAMP signaling to Epac/Rap1, protein kinase Cepsilon, and MEK/ERK.
    Eijkelkamp N, Wang H, Garza-Carbajal A, Willemen HL, Zwartkruis FJ, Wood JN, Dantzer R, Kelley KW, Heijnen CJ, Kavelaars A.
    J Neurosci; 2010 Sep 22; 30(38):12806-15. PubMed ID: 20861385
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  • 13. Epac, in synergy with cAMP-dependent protein kinase (PKA), is required for cAMP-mediated mitogenesis.
    Hochbaum D, Hong K, Barila G, Ribeiro-Neto F, Altschuler DL.
    J Biol Chem; 2008 Feb 22; 283(8):4464-8. PubMed ID: 18063584
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  • 14. PKA-dependent potentiation of glucose-stimulated insulin secretion by Epac activator 8-pCPT-2'-O-Me-cAMP-AM in human islets of Langerhans.
    Chepurny OG, Kelley GG, Dzhura I, Leech CA, Roe MW, Dzhura E, Li X, Schwede F, Genieser HG, Holz GG.
    Am J Physiol Endocrinol Metab; 2010 Mar 22; 298(3):E622-33. PubMed ID: 20009023
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  • 16. ROS/Epac1-mediated Rap1/NF-kappaB activation is required for the expression of BAFF in Raw264.7 murine macrophages.
    Moon EY, Lee JH, Lee JW, Song JH, Pyo S.
    Cell Signal; 2011 Sep 22; 23(9):1479-88. PubMed ID: 21596132
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  • 18. Epac activation ameliorates tubulointerstitial inflammation in diabetic nephropathy.
    Yang WX, Liu Y, Zhang SM, Wang HF, Liu YF, Liu JL, Li XH, Zeng MR, Han YZ, Liu FY, Sun L, Xiao L.
    Acta Pharmacol Sin; 2022 Mar 22; 43(3):659-671. PubMed ID: 34103688
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  • 19. The cAMP-activated GTP exchange factor, Epac1 upregulates plasma membrane and nuclear Akt kinase activities in 8-CPT-2-O-Me-cAMP-stimulated macrophages: Gene silencing of the cAMP-activated GTP exchange Epac1 prevents 8-CPT-2-O-Me-cAMP activation of Akt activity in macrophages.
    Misra UK, Kaczowka S, Pizzo SV.
    Cell Signal; 2008 Aug 22; 20(8):1459-70. PubMed ID: 18495429
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