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342 related items for PubMed ID: 21748766

  • 1. Conditional disruption of mouse HFE2 gene: maintenance of systemic iron homeostasis requires hepatic but not skeletal muscle hemojuvelin.
    Gkouvatsos K, Wagner J, Papanikolaou G, Sebastiani G, Pantopoulos K.
    Hepatology; 2011 Nov; 54(5):1800-7. PubMed ID: 21748766
    [Abstract] [Full Text] [Related]

  • 2. Hfe and Hjv exhibit overlapping functions for iron signaling to hepcidin.
    Kent P, Wilkinson N, Constante M, Fillebeen C, Gkouvatsos K, Wagner J, Buffler M, Becker C, Schümann K, Santos MM, Pantopoulos K.
    J Mol Med (Berl); 2015 May; 93(5):489-98. PubMed ID: 25609138
    [Abstract] [Full Text] [Related]

  • 3. Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload.
    Niederkofler V, Salie R, Arber S.
    J Clin Invest; 2005 Aug; 115(8):2180-6. PubMed ID: 16075058
    [Abstract] [Full Text] [Related]

  • 4. Evidence that inhibition of hemojuvelin shedding in response to iron is mediated through neogenin.
    Zhang AS, Anderson SA, Meyers KR, Hernandez C, Eisenstein RS, Enns CA.
    J Biol Chem; 2007 Apr 27; 282(17):12547-56. PubMed ID: 17331953
    [Abstract] [Full Text] [Related]

  • 5. Differing impact of the deletion of hemochromatosis-associated molecules HFE and transferrin receptor-2 on the iron phenotype of mice lacking bone morphogenetic protein 6 or hemojuvelin.
    Latour C, Besson-Fournier C, Meynard D, Silvestri L, Gourbeyre O, Aguilar-Martinez P, Schmidt PJ, Fleming MD, Roth MP, Coppin H.
    Hepatology; 2016 Jan 27; 63(1):126-37. PubMed ID: 26406355
    [Abstract] [Full Text] [Related]

  • 6. A high-fat diet modulates iron metabolism but does not promote liver fibrosis in hemochromatotic Hjv⁻/⁻ mice.
    Padda RS, Gkouvatsos K, Guido M, Mui J, Vali H, Pantopoulos K.
    Am J Physiol Gastrointest Liver Physiol; 2015 Feb 15; 308(4):G251-61. PubMed ID: 25501544
    [Abstract] [Full Text] [Related]

  • 7. The role of hepatocyte hemojuvelin in the regulation of bone morphogenic protein-6 and hepcidin expression in vivo.
    Zhang AS, Gao J, Koeberl DD, Enns CA.
    J Biol Chem; 2010 May 28; 285(22):16416-23. PubMed ID: 20363739
    [Abstract] [Full Text] [Related]

  • 8. Furin-mediated release of soluble hemojuvelin: a new link between hypoxia and iron homeostasis.
    Silvestri L, Pagani A, Camaschella C.
    Blood; 2008 Jan 15; 111(2):924-31. PubMed ID: 17938254
    [Abstract] [Full Text] [Related]

  • 9. Hepcidin regulation: ironing out the details.
    De Domenico I, Ward DM, Kaplan J.
    J Clin Invest; 2007 Jul 15; 117(7):1755-8. PubMed ID: 17607352
    [Abstract] [Full Text] [Related]

  • 10. Hepatic iron metabolism gene expression profiles in HFE associated hereditary hemochromatosis.
    Gleeson F, Ryan E, Barrett S, Russell J, Crowe J.
    Blood Cells Mol Dis; 2007 Jul 15; 38(1):37-44. PubMed ID: 17098454
    [Abstract] [Full Text] [Related]

  • 11. Effect of erythropoietin on hepcidin expression in hemojuvelin-mutant mice.
    Krijt J, Jonásová A, Neuwirtová R, Necas E.
    Blood Cells Mol Dis; 2010 Apr 15; 44(4):257-61. PubMed ID: 20219396
    [Abstract] [Full Text] [Related]

  • 12. Down-regulation of Bmp/Smad signaling by Tmprss6 is required for maintenance of systemic iron homeostasis.
    Finberg KE, Whittlesey RL, Fleming MD, Andrews NC.
    Blood; 2010 May 06; 115(18):3817-26. PubMed ID: 20200349
    [Abstract] [Full Text] [Related]

  • 13. Hepatic and extrahepatic expression of the new iron regulatory protein hemojuvelin.
    Rodriguez Martinez A, Niemelä O, Parkkila S.
    Haematologica; 2004 Dec 06; 89(12):1441-5. PubMed ID: 15590393
    [Abstract] [Full Text] [Related]

  • 14. Neogenin inhibits HJV secretion and regulates BMP-induced hepcidin expression and iron homeostasis.
    Lee DH, Zhou LJ, Zhou Z, Xie JX, Jung JU, Liu Y, Xi CX, Mei L, Xiong WC.
    Blood; 2010 Apr 15; 115(15):3136-45. PubMed ID: 20065295
    [Abstract] [Full Text] [Related]

  • 15. BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism.
    Andriopoulos B, Corradini E, Xia Y, Faasse SA, Chen S, Grgurevic L, Knutson MD, Pietrangelo A, Vukicevic S, Lin HY, Babitt JL.
    Nat Genet; 2009 Apr 15; 41(4):482-7. PubMed ID: 19252486
    [Abstract] [Full Text] [Related]

  • 16. Hepcidin downregulation by repeated bleeding is not mediated by soluble hemojuvelin.
    Krijt J, Fujikura Y, Sefc L, Vokurka M, Hlobenová T, Necas E.
    Physiol Res; 2010 Apr 15; 59(1):53-59. PubMed ID: 19249912
    [Abstract] [Full Text] [Related]

  • 17. Hemojuvelin: the hepcidin story continues.
    Malyszko J.
    Kidney Blood Press Res; 2009 Apr 15; 32(2):71-6. PubMed ID: 19287179
    [Abstract] [Full Text] [Related]

  • 18. Iron-induced expression of bone morphogenic protein 6 in intestinal cells is the main regulator of hepatic hepcidin expression in vivo.
    Arndt S, Maegdefrau U, Dorn C, Schardt K, Hellerbrand C, Bosserhoff AK.
    Gastroenterology; 2010 Jan 15; 138(1):372-82. PubMed ID: 19786029
    [Abstract] [Full Text] [Related]

  • 19. Effect of phlebotomy on hepcidin expression in hemojuvelin-mutant mice.
    Krijt J, Niederkofler V, Salie R, Sefc L, Pelichovská T, Vokurka M, Necas E.
    Blood Cells Mol Dis; 2007 Jan 15; 39(1):92-5. PubMed ID: 17395503
    [Abstract] [Full Text] [Related]

  • 20. Hepcidin-mediated hypoferremic response to acute inflammation requires a threshold of Bmp6/Hjv/Smad signaling.
    Fillebeen C, Wilkinson N, Charlebois E, Katsarou A, Wagner J, Pantopoulos K.
    Blood; 2018 Oct 25; 132(17):1829-1841. PubMed ID: 30213871
    [Abstract] [Full Text] [Related]

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