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115 related items for PubMed ID: 2176485

  • 1. Extracellular domain chimeras of the TSH and LH/CG receptors reveal the mid-region (amino acids 171-260) to play a vital role in high affinity TSH binding.
    Nagayama Y, Russo D, Chazenbalk GD, Wadsworth HL, Rapoport B.
    Biochem Biophys Res Commun; 1990 Dec 31; 173(3):1150-6. PubMed ID: 2176485
    [Abstract] [Full Text] [Related]

  • 2. Thyrotropin-luteinizing hormone/chorionic gonadotropin receptor extracellular domain chimeras as probes for thyrotropin receptor function.
    Nagayama Y, Wadsworth HL, Chazenbalk GD, Russo D, Seto P, Rapoport B.
    Proc Natl Acad Sci U S A; 1991 Feb 01; 88(3):902-5. PubMed ID: 1992482
    [Abstract] [Full Text] [Related]

  • 3. Eleven amino acids (Lys-201 to Lys-211) and 9 amino acids (Gly-222 to Leu-230) in the human thyrotropin receptor are involved in ligand binding.
    Nagayama Y, Russo D, Wadsworth HL, Chazenbalk GD, Rapoport B.
    J Biol Chem; 1991 Aug 15; 266(23):14926-30. PubMed ID: 1651314
    [Abstract] [Full Text] [Related]

  • 4. Thyrotropin stimulation of the lutropin/choriogonadotropin receptor: different sites mediate agonist activity and high affinity binding.
    Hidaka A, Ban T, Panesar NS, Minegishi T, Kohn LD, Tahara K.
    Thyroid; 1994 Aug 15; 4(4):447-57. PubMed ID: 7711510
    [Abstract] [Full Text] [Related]

  • 5. Chimeric studies of the extracellular domain of the rat thyrotropin (TSH) receptor: amino acids (268-304) in the TSH receptor are involved in ligand high affinity binding, but not in TSH receptor-specific signal transduction.
    Akamizu T, Inoue D, Kosugi S, Ban T, Kohn LD, Imura H, Mori T.
    Endocr J; 1993 Jun 15; 40(3):363-72. PubMed ID: 7920890
    [Abstract] [Full Text] [Related]

  • 6. Further studies of amino acids (268-304) in thyrotropin (TSH)--lutropin/chorionic gonadotropin (LH/CG) receptor chimeras: cysteine-301 is important in TSH binding and receptor tertiary structure.
    Akamizu T, Inoue D, Kosugi S, Kohn LD, Mori T.
    Thyroid; 1994 Jun 15; 4(1):43-8. PubMed ID: 8054860
    [Abstract] [Full Text] [Related]

  • 7. High affinity binding of thyrotropin (TSH) and thyroid-stimulating autoantibody for the TSH receptor extracellular domain.
    Nagayama Y, Takeshita A, Luo W, Ashizawa K, Yokoyama N, Nagataki S.
    Thyroid; 1994 Jun 15; 4(2):155-9. PubMed ID: 7919997
    [Abstract] [Full Text] [Related]

  • 8. Thyroid stimulatory autoantibodies in different patients with autoimmune thyroid disease do not all recognize the same components of the human thyrotropin receptor: selective role of receptor amino acids Ser25-Glu30.
    Nagayama Y, Rapoport B.
    J Clin Endocrinol Metab; 1992 Dec 15; 75(6):1425-30. PubMed ID: 1361193
    [Abstract] [Full Text] [Related]

  • 9. Binding domains of stimulatory and inhibitory thyrotropin (TSH) receptor autoantibodies determined with chimeric TSH-lutropin/chorionic gonadotropin receptors.
    Nagayama Y, Wadsworth HL, Russo D, Chazenbalk GD, Rapoport B.
    J Clin Invest; 1991 Jul 15; 88(1):336-40. PubMed ID: 1711544
    [Abstract] [Full Text] [Related]

  • 10. Studies on homologous desensitization of the thyrotropin receptor in 293 human embryonal kidney cells.
    Nagayama Y, Chazenbalk GD, Takeshita A, Kimura H, Ashizawa K, Yokoyama N, Rapoport B, Nagataki S.
    Endocrinology; 1994 Sep 15; 135(3):1060-5. PubMed ID: 8070347
    [Abstract] [Full Text] [Related]

  • 11. The C-terminal third of the human luteinizing hormone (LH) receptor is important for inositol phosphate release: analysis using chimeric human LH/follicle-stimulating hormone receptors.
    Hirsch B, Kudo M, Naro F, Conti M, Hsueh AJ.
    Mol Endocrinol; 1996 Sep 15; 10(9):1127-37. PubMed ID: 8885247
    [Abstract] [Full Text] [Related]

  • 12. Thyrotropin, like luteinizing hormone (LH) and chorionic gonadotropin (CG), increases cAMP and inositol phosphate levels in cells with recombinant human LH/CG receptor.
    Hidaka A, Minegishi T, Kohn LD.
    Biochem Biophys Res Commun; 1993 Oct 15; 196(1):187-95. PubMed ID: 8216292
    [Abstract] [Full Text] [Related]

  • 13. Insight into thyrotropin receptor cleavage by engineering the single polypeptide chain luteinizing hormone receptor into a cleaving, two subunit receptor.
    Chazenbalk GD, McLachlan SM, Chen CR, Rapoport B.
    Eur J Biochem; 2001 Apr 15; 268(8):2261-9. PubMed ID: 11298743
    [Abstract] [Full Text] [Related]

  • 14. Identification of separate determinants on the thyrotropin receptor reactive with Graves' thyroid-stimulating antibodies and with thyroid-stimulating blocking antibodies in idiopathic myxedema: these determinants have no homologous sequence on gonadotropin receptors.
    Kosugi S, Ban T, Akamizu T, Kohn LD.
    Mol Endocrinol; 1992 Feb 15; 6(2):168-80. PubMed ID: 1349156
    [Abstract] [Full Text] [Related]

  • 15. Immunoglobulins from Graves' disease patients interact with different sites on TSH receptor/LH-CG receptor chimeras than either TSH or immunoglobulins from idiopathic myxedema patients.
    Tahara K, Ban T, Minegishi T, Kohn LD.
    Biochem Biophys Res Commun; 1991 Aug 30; 179(1):70-7. PubMed ID: 1883391
    [Abstract] [Full Text] [Related]

  • 16. Characterization of a region of the lutropin receptor extracellular domain near transmembrane helix 1 that is important in ligand-mediated signaling.
    Alvarez CA, Narayan P, Huang J, Puett D.
    Endocrinology; 1999 Apr 30; 140(4):1775-82. PubMed ID: 10098515
    [Abstract] [Full Text] [Related]

  • 17. Differential effects of NaCl concentration on the constitutive activity of the thyrotropin and the luteinizing hormone/chorionic gonadotropin receptors.
    Cetani F, Tonacchera M, Vassart G.
    FEBS Lett; 1996 Jan 02; 378(1):27-31. PubMed ID: 8549796
    [Abstract] [Full Text] [Related]

  • 18. High-affinity binding of thyrotropin to the extracellular domain of its receptor transfected in Chinese hamster ovary cells.
    Shi Y, Zou M, Parhar RS, Farid NR.
    Thyroid; 1993 Jan 02; 3(2):129-33. PubMed ID: 8396480
    [Abstract] [Full Text] [Related]

  • 19. Role of the carboxyl-terminal half of the extracellular domain of the human thyrotropin receptor in signal transduction.
    Nagayama Y, Rapoport B.
    Endocrinology; 1992 Aug 02; 131(2):548-52. PubMed ID: 1322272
    [Abstract] [Full Text] [Related]

  • 20. Structure-function studies of the human thyrotropin receptor. Inhibition of binding of labeled thyrotropin (TSH) by synthetic human TSH receptor peptides.
    Morris JC, Bergert ER, McCormick DJ.
    J Biol Chem; 1993 May 25; 268(15):10900-5. PubMed ID: 8496155
    [Abstract] [Full Text] [Related]

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