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283 related items for PubMed ID: 21765465

  • 1. Absence of Wip1 partially rescues Atm deficiency phenotypes in mice.
    Darlington Y, Nguyen TA, Moon SH, Herron A, Rao P, Zhu C, Lu X, Donehower LA.
    Oncogene; 2012 Mar 01; 31(9):1155-65. PubMed ID: 21765465
    [Abstract] [Full Text] [Related]

  • 2. Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase.
    Shreeram S, Hee WK, Demidov ON, Kek C, Yamaguchi H, Fornace AJ, Anderson CW, Appella E, Bulavin DV.
    J Exp Med; 2006 Dec 25; 203(13):2793-9. PubMed ID: 17158963
    [Abstract] [Full Text] [Related]

  • 3. Wild-type p53-induced phosphatase 1 dephosphorylates histone variant gamma-H2AX and suppresses DNA double strand break repair.
    Moon SH, Lin L, Zhang X, Nguyen TA, Darlington Y, Waldman AS, Lu X, Donehower LA.
    J Biol Chem; 2010 Apr 23; 285(17):12935-47. PubMed ID: 20118229
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  • 5. Wip1 phosphatase modulates ATM-dependent signaling pathways.
    Shreeram S, Demidov ON, Hee WK, Yamaguchi H, Onishi N, Kek C, Timofeev ON, Dudgeon C, Fornace AJ, Anderson CW, Minami Y, Appella E, Bulavin DV.
    Mol Cell; 2006 Sep 01; 23(5):757-64. PubMed ID: 16949371
    [Abstract] [Full Text] [Related]

  • 6. Functional interaction of H2AX, NBS1, and p53 in ATM-dependent DNA damage responses and tumor suppression.
    Kang J, Ferguson D, Song H, Bassing C, Eckersdorff M, Alt FW, Xu Y.
    Mol Cell Biol; 2005 Jan 01; 25(2):661-70. PubMed ID: 15632067
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  • 7. Arsenic trioxide augments Chk2/p53-mediated apoptosis by inhibiting oncogenic Wip1 phosphatase.
    Yoda A, Toyoshima K, Watanabe Y, Onishi N, Hazaka Y, Tsukuda Y, Tsukada J, Kondo T, Tanaka Y, Minami Y.
    J Biol Chem; 2008 Jul 04; 283(27):18969-79. PubMed ID: 18482988
    [Abstract] [Full Text] [Related]

  • 8. Induction of p53 renders ATM-deficient mice refractory to hepatocarcinogenesis.
    Teoh N, Pyakurel P, Dan YY, Swisshelm K, Hou J, Mitchell C, Fausto N, Gu Y, Farrell G.
    Gastroenterology; 2010 Mar 04; 138(3):1155-65.e1-2. PubMed ID: 19919837
    [Abstract] [Full Text] [Related]

  • 9. Relationship between DNA double-strand break rejoining and cell survival after exposure to ionizing radiation in human fibroblast strains with differing ATM/p53 status: implications for evaluation of clinical radiosensitivity.
    Mirzayans R, Severin D, Murray D.
    Int J Radiat Oncol Biol Phys; 2006 Dec 01; 66(5):1498-505. PubMed ID: 17126209
    [Abstract] [Full Text] [Related]

  • 10. Reversal of the ATM/ATR-mediated DNA damage response by the oncogenic phosphatase PPM1D.
    Lu X, Nguyen TA, Donehower LA.
    Cell Cycle; 2005 Aug 01; 4(8):1060-4. PubMed ID: 15970689
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  • 12. Antioxidant N-acetyl cysteine reduces incidence and multiplicity of lymphoma in Atm deficient mice.
    Reliene R, Schiestl RH.
    DNA Repair (Amst); 2006 Jul 13; 5(7):852-9. PubMed ID: 16781197
    [Abstract] [Full Text] [Related]

  • 13. Impaired genomic stability and increased oxidative stress exacerbate different features of Ataxia-telangiectasia.
    Ziv S, Brenner O, Amariglio N, Smorodinsky NI, Galron R, Carrion DV, Zhang W, Sharma GG, Pandita RK, Agarwal M, Elkon R, Katzin N, Bar-Am I, Pandita TK, Kucherlapati R, Rechavi G, Shiloh Y, Barzilai A.
    Hum Mol Genet; 2005 Oct 01; 14(19):2929-43. PubMed ID: 16150740
    [Abstract] [Full Text] [Related]

  • 14. Dephosphorylation of γ-H2AX by WIP1: an important homeostatic regulatory event in DNA repair and cell cycle control.
    Moon SH, Nguyen TA, Darlington Y, Lu X, Donehower LA.
    Cell Cycle; 2010 Jun 01; 9(11):2092-6. PubMed ID: 20495376
    [Abstract] [Full Text] [Related]

  • 15. ATM and p21 cooperate to suppress aneuploidy and subsequent tumor development.
    Shen KC, Heng H, Wang Y, Lu S, Liu G, Deng CX, Brooks SC, Wang YA.
    Cancer Res; 2005 Oct 01; 65(19):8747-53. PubMed ID: 16204044
    [Abstract] [Full Text] [Related]

  • 16. Phosphorylation of p53 serine 18 upregulates apoptosis to suppress Myc-induced tumorigenesis.
    Sluss HK, Gannon H, Coles AH, Shen Q, Eischen CM, Jones SN.
    Mol Cancer Res; 2010 Feb 01; 8(2):216-22. PubMed ID: 20145032
    [Abstract] [Full Text] [Related]

  • 17. Loss of the ARF tumor suppressor reverses premature replicative arrest but not radiation hypersensitivity arising from disabled atm function.
    Kamijo T, van de Kamp E, Chong MJ, Zindy F, Diehl JA, Sherr CJ, McKinnon PJ.
    Cancer Res; 1999 May 15; 59(10):2464-9. PubMed ID: 10344759
    [Abstract] [Full Text] [Related]

  • 18. Abrogation of Wip1 expression by RITA-activated p53 potentiates apoptosis induction via activation of ATM and inhibition of HdmX.
    Spinnler C, Hedström E, Li H, de Lange J, Nikulenkov F, Teunisse AF, Verlaan-de Vries M, Grinkevich V, Jochemsen AG, Selivanova G.
    Cell Death Differ; 2011 Nov 15; 18(11):1736-45. PubMed ID: 21546907
    [Abstract] [Full Text] [Related]

  • 19. Augmented cancer resistance and DNA damage response phenotypes in PPM1D null mice.
    Nannenga B, Lu X, Dumble M, Van Maanen M, Nguyen TA, Sutton R, Kumar TR, Donehower LA.
    Mol Carcinog; 2006 Aug 15; 45(8):594-604. PubMed ID: 16652371
    [Abstract] [Full Text] [Related]

  • 20. STAT-1 facilitates the ATM activated checkpoint pathway following DNA damage.
    Townsend PA, Cragg MS, Davidson SM, McCormick J, Barry S, Lawrence KM, Knight RA, Hubank M, Chen PL, Latchman DS, Stephanou A.
    J Cell Sci; 2005 Apr 15; 118(Pt 8):1629-39. PubMed ID: 15784679
    [Abstract] [Full Text] [Related]

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