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283 related items for PubMed ID: 21765465

  • 21. Ataxia-telangiectasia mutated is not required for p53 induction and apoptosis in irradiated epithelial tissues.
    Gurley KE, Kemp CJ.
    Mol Cancer Res; 2007 Dec; 5(12):1312-8. PubMed ID: 18171989
    [Abstract] [Full Text] [Related]

  • 22. The oncogenic phosphatase WIP1 negatively regulates nucleotide excision repair.
    Nguyen TA, Slattery SD, Moon SH, Darlington YF, Lu X, Donehower LA.
    DNA Repair (Amst); 2010 Jul 01; 9(7):813-23. PubMed ID: 20451471
    [Abstract] [Full Text] [Related]

  • 23. Lack of ataxia telangiectasia mutated kinase induces structural and functional changes in the heart: role in β-adrenergic receptor-stimulated apoptosis.
    Foster CR, Zha Q, Daniel LL, Singh M, Singh K.
    Exp Physiol; 2012 Apr 01; 97(4):506-15. PubMed ID: 22179422
    [Abstract] [Full Text] [Related]

  • 24. Redundant and nonredundant functions of ATM and H2AX in αβ T-lineage lymphocytes.
    Yin B, Lee BS, Yang-Iott KS, Sleckman BP, Bassing CH.
    J Immunol; 2012 Aug 01; 189(3):1372-9. PubMed ID: 22730535
    [Abstract] [Full Text] [Related]

  • 25. Wip1-dependent signaling pathways in health and diseases.
    Zhu YH, Bulavin DV.
    Prog Mol Biol Transl Sci; 2012 Aug 01; 106():307-25. PubMed ID: 22340722
    [Abstract] [Full Text] [Related]

  • 26. Wip1 phosphatase-deficient mice exhibit defective T cell maturation due to sustained p53 activation.
    Schito ML, Demidov ON, Saito S, Ashwell JD, Appella E.
    J Immunol; 2006 Apr 15; 176(8):4818-25. PubMed ID: 16585576
    [Abstract] [Full Text] [Related]

  • 27. UV-induced histone H2AX phosphorylation and DNA damage related proteins accumulate and persist in nucleotide excision repair-deficient XP-B cells.
    Oh KS, Bustin M, Mazur SJ, Appella E, Kraemer KH.
    DNA Repair (Amst); 2011 Jan 02; 10(1):5-15. PubMed ID: 20947453
    [Abstract] [Full Text] [Related]

  • 28. Enhanced cytotoxicity of PARP inhibition in mantle cell lymphoma harbouring mutations in both ATM and p53.
    Williamson CT, Kubota E, Hamill JD, Klimowicz A, Ye R, Muzik H, Dean M, Tu L, Gilley D, Magliocco AM, McKay BC, Bebb DG, Lees-Miller SP.
    EMBO Mol Med; 2012 Jun 02; 4(6):515-27. PubMed ID: 22416035
    [Abstract] [Full Text] [Related]

  • 29. Atm heterozygous deficiency enhances development of mammary carcinomas in p53 heterozygous knockout mice.
    Umesako S, Fujisawa K, Iiga S, Mori N, Takahashi M, Hong DP, Song CW, Haga S, Imai S, Niwa O, Okumoto M.
    Breast Cancer Res; 2005 Jun 02; 7(1):R164-70. PubMed ID: 15642165
    [Abstract] [Full Text] [Related]

  • 30. Tumor suppression by p53 in the absence of Atm.
    Bailey SL, Gurley KE, Hoon-Kim K, Kelly-Spratt KS, Kemp CJ.
    Mol Cancer Res; 2008 Jul 02; 6(7):1185-92. PubMed ID: 18583527
    [Abstract] [Full Text] [Related]

  • 31. Ataxia telangiectasia mutated impacts insulin-like growth factor 1 signalling in skeletal muscle.
    Ching JK, Luebbert SH, Collins RL, Zhang Z, Marupudi N, Banerjee S, Hurd RD, Ralston L, Fisher JS.
    Exp Physiol; 2013 Feb 02; 98(2):526-35. PubMed ID: 22941977
    [Abstract] [Full Text] [Related]

  • 32. The Wip1 phosphatase PPM1D dephosphorylates SQ/TQ motifs in checkpoint substrates phosphorylated by PI3K-like kinases.
    Yamaguchi H, Durell SR, Chatterjee DK, Anderson CW, Appella E.
    Biochemistry; 2007 Nov 06; 46(44):12594-603. PubMed ID: 17939684
    [Abstract] [Full Text] [Related]

  • 33. Wip1 phosphatase is associated with chromatin and dephosphorylates gammaH2AX to promote checkpoint inhibition.
    Macůrek L, Lindqvist A, Voets O, Kool J, Vos HR, Medema RH.
    Oncogene; 2010 Apr 15; 29(15):2281-91. PubMed ID: 20101220
    [Abstract] [Full Text] [Related]

  • 34. WIP1, a homeostatic regulator of the DNA damage response, is targeted by HIPK2 for phosphorylation and degradation.
    Choi DW, Na W, Kabir MH, Yi E, Kwon S, Yeom J, Ahn JW, Choi HH, Lee Y, Seo KW, Shin MK, Park SH, Yoo HY, Isono K, Koseki H, Kim ST, Lee C, Kwon YK, Choi CY.
    Mol Cell; 2013 Aug 08; 51(3):374-85. PubMed ID: 23871434
    [Abstract] [Full Text] [Related]

  • 35. PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints.
    Lu X, Nannenga B, Donehower LA.
    Genes Dev; 2005 May 15; 19(10):1162-74. PubMed ID: 15870257
    [Abstract] [Full Text] [Related]

  • 36. The DNA damage checkpoint protein ATM promotes hepatocellular apoptosis and fibrosis in a mouse model of non-alcoholic fatty liver disease.
    Daugherity EK, Balmus G, Al Saei A, Moore ES, Abi Abdallah D, Rogers AB, Weiss RS, Maurer KJ.
    Cell Cycle; 2012 May 15; 11(10):1918-28. PubMed ID: 22544329
    [Abstract] [Full Text] [Related]

  • 37. Squalene Inhibits ATM-Dependent Signaling in γIR-Induced DNA Damage Response through Induction of Wip1 Phosphatase.
    Tatewaki N, Konishi T, Nakajima Y, Nishida M, Saito M, Eitsuka T, Sakamaki T, Ikekawa N, Nishida H.
    PLoS One; 2016 May 15; 11(1):e0147570. PubMed ID: 26824362
    [Abstract] [Full Text] [Related]

  • 38. Antioxidants suppress lymphoma and increase longevity in Atm-deficient mice.
    Reliene R, Schiestl RH.
    J Nutr; 2007 Jan 15; 137(1 Suppl):229S-232S. PubMed ID: 17182831
    [Abstract] [Full Text] [Related]

  • 39. Atm-deficient mice exhibit increased sensitivity to dextran sulfate sodium-induced colitis characterized by elevated DNA damage and persistent immune activation.
    Westbrook AM, Schiestl RH.
    Cancer Res; 2010 Mar 01; 70(5):1875-84. PubMed ID: 20179206
    [Abstract] [Full Text] [Related]

  • 40. The Wip1 phosphatase (PPM1D) antagonizes activation of the Chk2 tumour suppressor kinase.
    Oliva-Trastoy M, Berthonaud V, Chevalier A, Ducrot C, Marsolier-Kergoat MC, Mann C, Leteurtre F.
    Oncogene; 2007 Mar 01; 26(10):1449-58. PubMed ID: 16936775
    [Abstract] [Full Text] [Related]

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