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Journal Abstract Search
173 related items for PubMed ID: 21778327
1. Features of the Streptomyces hygroscopicus HtpG reveal how partial geldanamycin resistance can arise with mutation to the ATP binding pocket of a eukaryotic Hsp90. Millson SH, Chua CS, Roe SM, Polier S, Solovieva S, Pearl LH, Sim TS, Prodromou C, Piper PW. FASEB J; 2011 Nov; 25(11):3828-37. PubMed ID: 21778327 [Abstract] [Full Text] [Related]
3. Mechanistic studies on Hsp90 inhibition by ansamycin derivatives. Onuoha SC, Mukund SR, Coulstock ET, Sengerovà B, Shaw J, McLaughlin SH, Jackson SE. J Mol Biol; 2007 Sep 14; 372(2):287-97. PubMed ID: 17662999 [Abstract] [Full Text] [Related]
4. Characterization of tailoring genes involved in the modification of geldanamycin polyketide in Streptomyces hygroscopicus JCM4427. Shin JC, Na Z, Lee DH, Kim WC, Lee K, Shen YM, Paik SG, Hong YS, Lee JJ. J Microbiol Biotechnol; 2008 Jun 14; 18(6):1101-8. PubMed ID: 18600054 [Abstract] [Full Text] [Related]
6. Spotlight on the microbes that produce heat shock protein 90-targeting antibiotics. Piper PW, Millson SH. Open Biol; 2012 Dec 12; 2(12):120138. PubMed ID: 23271830 [Abstract] [Full Text] [Related]
8. Binding of immunophilins to the 90 kDa heat shock protein (hsp90) via a tetratricopeptide repeat domain is a conserved protein interaction in plants. Owens-Grillo JK, Stancato LF, Hoffmann K, Pratt WB, Krishna P. Biochemistry; 1996 Dec 03; 35(48):15249-55. PubMed ID: 8952474 [Abstract] [Full Text] [Related]
9. Inside the Hsp90 inhibitors binding mode through induced fit docking. Lauria A, Ippolito M, Almerico AM. J Mol Graph Model; 2009 Feb 03; 27(6):712-22. PubMed ID: 19084447 [Abstract] [Full Text] [Related]
10. Modulation of Hsf1 activity by novobiocin and geldanamycin. Conde R, Belak ZR, Nair M, O'Carroll RF, Ovsenek N. Biochem Cell Biol; 2009 Dec 03; 87(6):845-51. PubMed ID: 19935870 [Abstract] [Full Text] [Related]
11. New non-quinone geldanamycin analogs from genetically engineered Streptomyces hygroscopicus. Wu CZ, Moon AN, Jang JH, Lee D, Kang SY, Park JT, Ahn JS, Hwang BY, Kim YH, Lee HS, Hong YS. J Antibiot (Tokyo); 2011 Jun 03; 64(6):461-3. PubMed ID: 21448187 [No Abstract] [Full Text] [Related]
12. New geldanamycin analogs from Streptomyces hygroscopicus. Wu CZ, Jang JH, Ahn JS, Hong YS. J Microbiol Biotechnol; 2012 Nov 03; 22(11):1478-81. PubMed ID: 23124337 [Abstract] [Full Text] [Related]
13. Heat shock protein 90 regulates development in Dictyostelium discoideum. Sawarkar R, Roy N, Rao S, Raman S, Venketesh S, Suguna K, Tatu U. J Mol Biol; 2008 Oct 31; 383(1):24-35. PubMed ID: 18718841 [Abstract] [Full Text] [Related]
14. Rational biosynthetic engineering for optimization of geldanamycin analogues. Kim W, Lee D, Hong SS, Na Z, Shin JC, Roh SH, Wu CZ, Choi O, Lee K, Shen YM, Paik SG, Lee JJ, Hong YS. Chembiochem; 2009 May 04; 10(7):1243-51. PubMed ID: 19308924 [Abstract] [Full Text] [Related]
16. Interaction of radicicol with members of the heat shock protein 90 family of molecular chaperones. Schulte TW, Akinaga S, Murakata T, Agatsuma T, Sugimoto S, Nakano H, Lee YS, Simen BB, Argon Y, Felts S, Toft DO, Neckers LM, Sharma SV. Mol Endocrinol; 1999 Sep 04; 13(9):1435-48. PubMed ID: 10478836 [Abstract] [Full Text] [Related]
17. Geldanamycin-induced PCNA degradation in isolated Hsp90 complex from cancer cells. Wang X, Heuvelman DM, Carroll JA, Dufield DR, Masferrer JL. Cancer Invest; 2010 Jul 04; 28(6):635-41. PubMed ID: 20394503 [Abstract] [Full Text] [Related]