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219 related items for PubMed ID: 21784853

  • 1. Distinct involvement of the Gab1 and Grb2 adaptor proteins in signal transduction by the related receptor tyrosine kinases RON and MET.
    Chaudhuri A, Xie MH, Yang B, Mahapatra K, Liu J, Marsters S, Bodepudi S, Ashkenazi A.
    J Biol Chem; 2011 Sep 16; 286(37):32762-74. PubMed ID: 21784853
    [Abstract] [Full Text] [Related]

  • 2. Identification of an atypical Grb2 carboxyl-terminal SH3 domain binding site in Gab docking proteins reveals Grb2-dependent and -independent recruitment of Gab1 to receptor tyrosine kinases.
    Lock LS, Royal I, Naujokas MA, Park M.
    J Biol Chem; 2000 Oct 06; 275(40):31536-45. PubMed ID: 10913131
    [Abstract] [Full Text] [Related]

  • 3. Coupling of Gab1 to c-Met, Grb2, and Shp2 mediates biological responses.
    Schaeper U, Gehring NH, Fuchs KP, Sachs M, Kempkes B, Birchmeier W.
    J Cell Biol; 2000 Jun 26; 149(7):1419-32. PubMed ID: 10871282
    [Abstract] [Full Text] [Related]

  • 4. Gab1 coupling to the HGF/Met receptor multifunctional docking site requires binding of Grb2 and correlates with the transforming potential.
    Bardelli A, Longati P, Gramaglia D, Stella MC, Comoglio PM.
    Oncogene; 1997 Dec 18; 15(25):3103-11. PubMed ID: 9444958
    [Abstract] [Full Text] [Related]

  • 5. Anti-apoptotic role of caspase-cleaved GAB1 adaptor protein in hepatocyte growth factor/scatter factor-MET receptor protein signaling.
    Le Goff A, Ji Z, Leclercq B, Bourette RP, Mougel A, Guerardel C, de Launoit Y, Vicogne J, Goormachtigh G, Fafeur V.
    J Biol Chem; 2012 Oct 12; 287(42):35382-35396. PubMed ID: 22915589
    [Abstract] [Full Text] [Related]

  • 6. Association of the multisubstrate docking protein Gab1 with the hepatocyte growth factor receptor requires a functional Grb2 binding site involving tyrosine 1356.
    Nguyen L, Holgado-Madruga M, Maroun C, Fixman ED, Kamikura D, Fournier T, Charest A, Tremblay ML, Wong AJ, Park M.
    J Biol Chem; 1997 Aug 15; 272(33):20811-9. PubMed ID: 9252406
    [Abstract] [Full Text] [Related]

  • 7. Grb2-independent recruitment of Gab1 requires the C-terminal lobe and structural integrity of the Met receptor kinase domain.
    Lock LS, Frigault MM, Saucier C, Park M.
    J Biol Chem; 2003 Aug 08; 278(32):30083-90. PubMed ID: 12766170
    [Abstract] [Full Text] [Related]

  • 8. Interaction between Gab1 and the c-Met receptor tyrosine kinase is responsible for epithelial morphogenesis.
    Weidner KM, Di Cesare S, Sachs M, Brinkmann V, Behrens J, Birchmeier W.
    Nature; 1996 Nov 14; 384(6605):173-6. PubMed ID: 8906793
    [Abstract] [Full Text] [Related]

  • 9. ShcA and Grb2 mediate polyoma middle T antigen-induced endothelial transformation and Gab1 tyrosine phosphorylation.
    Ong SH, Dilworth S, Hauck-Schmalenberger I, Pawson T, Kiefer F.
    EMBO J; 2001 Nov 15; 20(22):6327-36. PubMed ID: 11707404
    [Abstract] [Full Text] [Related]

  • 10. MUC20 suppresses the hepatocyte growth factor-induced Grb2-Ras pathway by binding to a multifunctional docking site of met.
    Higuchi T, Orita T, Katsuya K, Yamasaki Y, Akiyama K, Li H, Yamamoto T, Saito Y, Nakamura M.
    Mol Cell Biol; 2004 Sep 15; 24(17):7456-68. PubMed ID: 15314156
    [Abstract] [Full Text] [Related]

  • 11. Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo.
    Schaeper U, Vogel R, Chmielowiec J, Huelsken J, Rosario M, Birchmeier W.
    Proc Natl Acad Sci U S A; 2007 Sep 25; 104(39):15376-81. PubMed ID: 17881575
    [Abstract] [Full Text] [Related]

  • 12. The multisubstrate adapter Gab1 regulates hepatocyte growth factor (scatter factor)-c-Met signaling for cell survival and DNA repair.
    Fan S, Ma YX, Gao M, Yuan RQ, Meng Q, Goldberg ID, Rosen EM.
    Mol Cell Biol; 2001 Aug 25; 21(15):4968-84. PubMed ID: 11438654
    [Abstract] [Full Text] [Related]

  • 13. The multisubstrate docking site of the MET receptor is dispensable for MET-mediated RAS signaling and cell scattering.
    Tulasne D, Paumelle R, Weidner KM, Vandenbunder B, Fafeur V.
    Mol Biol Cell; 1999 Mar 25; 10(3):551-65. PubMed ID: 10069803
    [Abstract] [Full Text] [Related]

  • 14. Oncogenic Met receptor induces cell-cycle progression in Xenopus oocytes independent of direct Grb2 and Shc binding or Mos synthesis, but requires phosphatidylinositol 3-kinase and Raf signaling.
    Mood K, Saucier C, Ishimura A, Bong YS, Lee HS, Park M, Daar IO.
    J Cell Physiol; 2006 Apr 25; 207(1):271-85. PubMed ID: 16331688
    [Abstract] [Full Text] [Related]

  • 15. Non-canonical dynamic mechanisms of interaction between the p66Shc protein and Met receptor.
    Landry M, Pomerleau V, Saucier C.
    Biochem J; 2016 Jun 01; 473(11):1617-27. PubMed ID: 27048591
    [Abstract] [Full Text] [Related]

  • 16. Macrophage stimulating protein preserves blood brain barrier integrity after intracerebral hemorrhage through recepteur d'origine nantais dependent GAB1/Src/β-catenin pathway activation in a mouse model.
    Lu T, Wang Z, Prativa S, Xu Y, Wang T, Zhang Y, Yu L, Xu N, Tang J, You W, Chen G, Zhang JH.
    J Neurochem; 2019 Jan 01; 148(1):114-126. PubMed ID: 30380151
    [Abstract] [Full Text] [Related]

  • 17. The multi-site docking protein Grb2-associated binder 1 (Gab1) enhances interleukin-6-induced MAPK-pathway activation in an SHP2-, Grb2-, and time-dependent manner.
    Bongartz H, Gille K, Hessenkemper W, Mandel K, Lewitzky M, Feller SM, Schaper F.
    Cell Commun Signal; 2019 Oct 24; 17(1):135. PubMed ID: 31651330
    [Abstract] [Full Text] [Related]

  • 18. Efficient cellular transformation by the Met oncoprotein requires a functional Grb2 binding site and correlates with phosphorylation of the Grb2-associated proteins, Cbl and Gab1.
    Fixman ED, Holgado-Madruga M, Nguyen L, Kamikura DM, Fournier TM, Wong AJ, Park M.
    J Biol Chem; 1997 Aug 08; 272(32):20167-72. PubMed ID: 9242692
    [Abstract] [Full Text] [Related]

  • 19. Characterization of intracellular signals via tyrosine 1062 in RET activated by glial cell line-derived neurotrophic factor.
    Hayashi H, Ichihara M, Iwashita T, Murakami H, Shimono Y, Kawai K, Kurokawa K, Murakumo Y, Imai T, Funahashi H, Nakao A, Takahashi M.
    Oncogene; 2000 Sep 14; 19(39):4469-75. PubMed ID: 11002419
    [Abstract] [Full Text] [Related]

  • 20. Identification of SNT/FRS2 docking site on RET receptor tyrosine kinase and its role for signal transduction.
    Kurokawa K, Iwashita T, Murakami H, Hayashi H, Kawai K, Takahashi M.
    Oncogene; 2001 Apr 12; 20(16):1929-38. PubMed ID: 11360177
    [Abstract] [Full Text] [Related]

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