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275 related items for PubMed ID: 21787672

  • 1. Zearalenone activates pregnane X receptor, constitutive androstane receptor and aryl hydrocarbon receptor and corresponding phase I target genes mRNA in primary cultures of human hepatocytes.
    Ayed-Boussema I, Pascussi JM, Maurel P, Bacha H, Hassen W.
    Environ Toxicol Pharmacol; 2011 Jan; 31(1):79-87. PubMed ID: 21787672
    [Abstract] [Full Text] [Related]

  • 2. Effect of aflatoxin B1 on nuclear receptors PXR, CAR, and AhR and their target cytochromes P450 mRNA expression in primary cultures of human hepatocytes.
    Ayed-Boussema I, Pascussi JM, Maurel P, Bacha H, Hassen W.
    Int J Toxicol; 2012 Jan; 31(1):86-93. PubMed ID: 21994236
    [Abstract] [Full Text] [Related]

  • 3. Cytochrome P450 enzyme levels in HepG2 cells and cryopreserved primary human hepatocytes and their induction in HepG2 cells.
    Westerink WM, Schoonen WG.
    Toxicol In Vitro; 2007 Dec; 21(8):1581-91. PubMed ID: 17637504
    [Abstract] [Full Text] [Related]

  • 4. The mycotoxin, patulin, increases the expression of PXR and AhR and their target cytochrome P450s in primary cultured human hepatocytes.
    Ayed-Boussema I, Pascussi JM, Rjiba K, Maurel P, Bacha H, Hassen W.
    Drug Chem Toxicol; 2012 Jul; 35(3):241-50. PubMed ID: 21939362
    [Abstract] [Full Text] [Related]

  • 5. Examination of Zolpidem effects on AhR- and PXR-dependent expression of drug-metabolizing cytochromes P450 in primary cultures of human hepatocytes.
    Bachleda P, Vrzal R, Pivnicka J, Cvek B, Dvorak Z.
    Toxicol Lett; 2009 Dec 01; 191(1):74-8. PubMed ID: 19686824
    [Abstract] [Full Text] [Related]

  • 6. Differential effect of meclizine on the activity of human pregnane X receptor and constitutive androstane receptor.
    Lau AJ, Yang G, Rajaraman G, Baucom CC, Chang TK.
    J Pharmacol Exp Ther; 2011 Mar 01; 336(3):816-26. PubMed ID: 21131266
    [Abstract] [Full Text] [Related]

  • 7. Ketoconazole and miconazole are antagonists of the human glucocorticoid receptor: consequences on the expression and function of the constitutive androstane receptor and the pregnane X receptor.
    Duret C, Daujat-Chavanieu M, Pascussi JM, Pichard-Garcia L, Balaguer P, Fabre JM, Vilarem MJ, Maurel P, Gerbal-Chaloin S.
    Mol Pharmacol; 2006 Jul 01; 70(1):329-39. PubMed ID: 16608920
    [Abstract] [Full Text] [Related]

  • 8. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
    Cerveny L, Svecova L, Anzenbacherova E, Vrzal R, Staud F, Dvorak Z, Ulrichova J, Anzenbacher P, Pavek P.
    Drug Metab Dispos; 2007 Jul 01; 35(7):1032-41. PubMed ID: 17392393
    [Abstract] [Full Text] [Related]

  • 9. Ochratoxin A induces CYP3A4, 2B6, 3A5, 2C9, 1A1, and CYP1A2 gene expression in primary cultured human hepatocytes: a possible activation of nuclear receptors.
    Ayed-Boussema I, Pascussi JM, Zaied C, Maurel P, Bacha H, Hassen W.
    Drug Chem Toxicol; 2012 Jan 01; 35(1):71-80. PubMed ID: 21834667
    [Abstract] [Full Text] [Related]

  • 10. Benzodiazepines medazepam and midazolam are activators of pregnane X receptor and weak inducers of CYP3A4: investigation in primary cultures of human hepatocytes and hepatocarcinoma cell lines.
    Vrzal R, Kubesova K, Pavek P, Dvorak Z.
    Toxicol Lett; 2010 Mar 15; 193(2):183-8. PubMed ID: 20080160
    [Abstract] [Full Text] [Related]

  • 11. Induction of CYP2C genes in human hepatocytes in primary culture.
    Gerbal-Chaloin S, Pascussi JM, Pichard-Garcia L, Daujat M, Waechter F, Fabre JM, Carrère N, Maurel P.
    Drug Metab Dispos; 2001 Mar 15; 29(3):242-51. PubMed ID: 11181490
    [Abstract] [Full Text] [Related]

  • 12. Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor.
    Casabar RC, Das PC, Dekrey GK, Gardiner CS, Cao Y, Rose RL, Wallace AD.
    Toxicol Appl Pharmacol; 2010 Jun 15; 245(3):335-43. PubMed ID: 20361990
    [Abstract] [Full Text] [Related]

  • 13. TSU-16, (Z)-3-[(2,4-dimethylpyrrol-5-yl)methylidenyl]-2-indolinone, is a potent activator of aryl hydrocarbon receptor and increases CYP1A1 and CYP1A2 expression in human hepatocytes.
    Matsuoka-Kawano K, Yoshinari K, Nagayama S, Yamazoe Y.
    Chem Biol Interact; 2010 Apr 15; 185(1):33-41. PubMed ID: 20171196
    [Abstract] [Full Text] [Related]

  • 14. Comparison of immortalized Fa2N-4 cells and human hepatocytes as in vitro models for cytochrome P450 induction.
    Hariparsad N, Carr BA, Evers R, Chu X.
    Drug Metab Dispos; 2008 Jun 15; 36(6):1046-55. PubMed ID: 18332078
    [Abstract] [Full Text] [Related]

  • 15. The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor.
    Ding X, Lichti K, Staudinger JL.
    Toxicol Sci; 2006 Jun 15; 91(2):448-55. PubMed ID: 16547076
    [Abstract] [Full Text] [Related]

  • 16. Simultaneous assessment of cytochrome P450 activity in cultured human hepatocytes for compound-mediated induction of CYP3A4, CYP2B6, and CYP1A2.
    Rhodes SP, Otten JN, Hingorani GP, Hartley DP, Franklin RB.
    J Pharmacol Toxicol Methods; 2011 Jun 15; 63(3):223-6. PubMed ID: 21111054
    [Abstract] [Full Text] [Related]

  • 17. Endocrine disrupting effects of zearalenone, alpha- and beta-zearalenol at the level of nuclear receptor binding and steroidogenesis.
    Frizzell C, Ndossi D, Verhaegen S, Dahl E, Eriksen G, Sørlie M, Ropstad E, Muller M, Elliott CT, Connolly L.
    Toxicol Lett; 2011 Oct 10; 206(2):210-7. PubMed ID: 21803136
    [Abstract] [Full Text] [Related]

  • 18. Differences in Gene Regulation by Dual Ligands of Nuclear Receptors Constitutive Androstane Receptor (CAR) and Pregnane X Receptor (PXR) in HepG2 Cells Stably Expressing CAR/PXR.
    Kanno Y, Tanuma N, Yazawa S, Zhao S, Inaba M, Nakamura S, Nemoto K, Inouye Y.
    Drug Metab Dispos; 2016 Aug 10; 44(8):1158-63. PubMed ID: 27197997
    [Abstract] [Full Text] [Related]

  • 19. Constitutive androstane receptor transcriptionally activates human CYP1A1 and CYP1A2 genes through a common regulatory element in the 5'-flanking region.
    Yoshinari K, Yoda N, Toriyabe T, Yamazoe Y.
    Biochem Pharmacol; 2010 Jan 15; 79(2):261-9. PubMed ID: 19682433
    [Abstract] [Full Text] [Related]

  • 20. Characterization of human cytochrome P450 induction by pesticides.
    Abass K, Lämsä V, Reponen P, Küblbeck J, Honkakoski P, Mattila S, Pelkonen O, Hakkola J.
    Toxicology; 2012 Mar 29; 294(1):17-26. PubMed ID: 22310298
    [Abstract] [Full Text] [Related]

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