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Journal Abstract Search

225 related items for PubMed ID: 21789526

  • 1. Triptolide exhibits anti-inflammatory, anti-catabolic as well as anabolic effects and suppresses TLR expression and MAPK activity in IL-1β treated human intervertebral disc cells.
    Klawitter M, Quero L, Klasen J, Liebscher T, Nerlich A, Boos N, Wuertz K.
    Eur Spine J; 2012 Aug; 21 Suppl 6(Suppl 6):S850-9. PubMed ID: 21789526
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  • 3. Expression and regulation of toll-like receptors (TLRs) in human intervertebral disc cells.
    Klawitter M, Hakozaki M, Kobayashi H, Krupkova O, Quero L, Ospelt C, Gay S, Hausmann O, Liebscher T, Meier U, Sekiguchi M, Konno S, Boos N, Ferguson SJ, Wuertz K.
    Eur Spine J; 2014 Sep; 23(9):1878-91. PubMed ID: 24997157
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  • 4. Triptolide suppresses interleukin-1beta-induced human beta-defensin-2 mRNA expression through inhibition of transcriptional activation of NF-kappaB in A549 cells.
    Jang BC, Lim KJ, Choi IH, Suh MH, Park JG, Mun KC, Bae JH, Shin DH, Suh SI.
    Int J Mol Med; 2007 May; 19(5):757-63. PubMed ID: 17390080
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  • 5. IL-1β/HMGB1 signalling promotes the inflammatory cytokines release via TLR signalling in human intervertebral disc cells.
    Fang F, Jiang D.
    Biosci Rep; 2016 Oct; 36(5):. PubMed ID: 27512095
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  • 6. Piperine mediates LPS induced inflammatory and catabolic effects in rat intervertebral disc.
    Li Y, Li K, Hu Y, Xu B, Zhao J.
    Int J Clin Exp Pathol; 2015 Oct; 8(6):6203-13. PubMed ID: 26261497
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  • 7. Crocin exerts anti-inflammatory and anti-catabolic effects on rat intervertebral discs by suppressing the activation of JNK.
    Li K, Li Y, Ma Z, Zhao J.
    Int J Mol Med; 2015 Nov; 36(5):1291-9. PubMed ID: 26648423
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  • 8. Tanshinone IIA represses inflammatory response and reduces radiculopathic pain by inhibiting IRAK-1 and NF-κB/p38/JNK signaling.
    Li W, Zhang Y, Xing C, Zhang M.
    Int Immunopharmacol; 2015 Sep; 28(1):382-9. PubMed ID: 26163178
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  • 10. Anti-inflammatory effects of triptolide in LPS-induced acute lung injury in mice.
    Wei D, Huang Z.
    Inflammation; 2014 Aug; 37(4):1307-16. PubMed ID: 24706025
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  • 11. Triptolide Attenuates Inflammatory Response in Membranous Glomerulo-Nephritis Rat via Downregulation of NF-κB Signaling Pathway.
    Zhou Y, Hong Y, Huang H.
    Kidney Blood Press Res; 2016 Aug; 41(6):901-910. PubMed ID: 27871079
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  • 12. Nerve Growth Factor Is Regulated by Toll-Like Receptor 2 in Human Intervertebral Discs.
    Krock E, Currie JB, Weber MH, Ouellet JA, Stone LS, Rosenzweig DH, Haglund L.
    J Biol Chem; 2016 Feb 12; 291(7):3541-51. PubMed ID: 26668319
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  • 16. IL-1β-pre-conditioned mesenchymal stem/stromal cells' secretome modulates the inflammatory response and aggrecan deposition in intervertebral disc.
    Ferreira JR, Teixeira GQ, Neto E, Ribeiro-Machado C, Silva AM, Caldeira J, Leite Pereira C, Bidarra S, Maia AF, Lamghari M, Barbosa MA, Gonçalves RM.
    Eur Cell Mater; 2021 Apr 20; 41():431-453. PubMed ID: 33877647
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  • 18. Bone morphogenetic protein-7 antagonizes tumor necrosis factor-α-induced activation of nuclear factor κB and up-regulation of the ADAMTS, leading to decreased degradation of disc matrix macromolecules aggrecan and collagen II.
    Wang Z, Hutton WC, Yoon ST.
    Spine J; 2014 Mar 01; 14(3):505-12. PubMed ID: 24176808
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  • 19. Curcuma DMSO extracts and curcumin exhibit an anti-inflammatory and anti-catabolic effect on human intervertebral disc cells, possibly by influencing TLR2 expression and JNK activity.
    Klawitter M, Quero L, Klasen J, Gloess AN, Klopprogge B, Hausmann O, Boos N, Wuertz K.
    J Inflamm (Lond); 2012 Aug 21; 9(1):29. PubMed ID: 22909087
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  • 20. Triptolide (TPL) inhibits global transcription by inducing proteasome-dependent degradation of RNA polymerase II (Pol II).
    Wang Y, Lu JJ, He L, Yu Q.
    PLoS One; 2011 Aug 21; 6(9):e23993. PubMed ID: 21931633
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