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202 related items for PubMed ID: 21795336

  • 1. The major determinant of attenuation in mice of the Candid1 vaccine for Argentine hemorrhagic fever is located in the G2 glycoprotein transmembrane domain.
    Albariño CG, Bird BH, Chakrabarti AK, Dodd KA, Flint M, Bergeron E, White DM, Nichol ST.
    J Virol; 2011 Oct; 85(19):10404-8. PubMed ID: 21795336
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  • 3. Substitutions in the glycoprotein (GP) of the Candid#1 vaccine strain of Junin virus increase dependence on human transferrin receptor 1 for entry and destabilize the metastable conformation of GP.
    Droniou-Bonzom ME, Reignier T, Oldenburg JE, Cox AU, Exline CM, Rathbun JY, Cannon PM.
    J Virol; 2011 Dec; 85(24):13457-62. PubMed ID: 21976641
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  • 4. Rescue from cloned cDNAs and in vivo characterization of recombinant pathogenic Romero and live-attenuated Candid #1 strains of Junin virus, the causative agent of Argentine hemorrhagic fever disease.
    Emonet SF, Seregin AV, Yun NE, Poussard AL, Walker AG, de la Torre JC, Paessler S.
    J Virol; 2011 Feb; 85(4):1473-83. PubMed ID: 21123388
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  • 6. Genomic features of attenuated Junín virus vaccine strain candidate.
    Goñi SE, Iserte JA, Ambrosio AM, Romanowski V, Ghiringhelli PD, Lozano ME.
    Virus Genes; 2006 Feb; 32(1):37-41. PubMed ID: 16525733
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  • 7. The Glycoprotein of the Live-Attenuated Junin Virus Vaccine Strain Induces Endoplasmic Reticulum Stress and Forms Aggregates prior to Degradation in the Lysosome.
    Manning JT, Yun NE, Seregin AV, Koma T, Sattler RA, Ezeomah C, Huang C, de la Torre JC, Paessler S.
    J Virol; 2020 Mar 31; 94(8):. PubMed ID: 31996435
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  • 9. Machupo Virus Expressing GPC of the Candid#1 Vaccine Strain of Junin Virus Is Highly Attenuated and Immunogenic.
    Koma T, Patterson M, Huang C, Seregin AV, Maharaj PD, Miller M, Smith JN, Walker AG, Hallam S, Paessler S.
    J Virol; 2016 Feb 01; 90(3):1290-7. PubMed ID: 26581982
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  • 11. Restoration of virulence in the attenuated Candid#1 vaccine virus requires reversion at both positions 168 and 427 in the envelope glycoprotein GPC.
    Nunberg JH, Westover JB, York J, Jung KH, Bailey KW, Boardman KM, Li M, Furnell RS, Wasson SR, Murray JS, Kaundal R, Thomas AJ, Gowen BB.
    J Virol; 2024 Apr 16; 98(4):e0011224. PubMed ID: 38506509
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  • 12. The Ectodomain of Glycoprotein from the Candid#1 Vaccine Strain of Junin Virus Rendered Machupo Virus Partially Attenuated in Mice Lacking IFN-αβ/γ Receptor.
    Koma T, Huang C, Aronson JF, Walker AG, Miller M, Smith JN, Patterson M, Paessler S.
    PLoS Negl Trop Dis; 2016 Aug 16; 10(8):e0004969. PubMed ID: 27580122
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  • 13. The glycoprotein precursor gene of Junin virus determines the virulence of the Romero strain and the attenuation of the Candid #1 strain in a representative animal model of Argentine hemorrhagic fever.
    Seregin AV, Yun NE, Miller M, Aronson J, Smith JK, Walker AG, Smith JN, Huang C, Manning JT, de la Torre JC, Paessler S.
    J Virol; 2015 Jun 16; 89(11):5949-56. PubMed ID: 25810546
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  • 14. IgG subclasses in human immune response to wild and attenuated (vaccine) Junin virus infection.
    del Carmen Saavedra M, Sottosanti JM, Riera L, Ambrosio AM.
    J Med Virol; 2003 Mar 16; 69(3):447-50. PubMed ID: 12526057
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  • 15. Molecular analysis of the virulence attenuation process in Junín virus vaccine genealogy.
    Goñi SE, Iserte JA, Stephan BI, Borio CS, Ghiringhelli PD, Lozano ME.
    Virus Genes; 2010 Jun 16; 40(3):320-8. PubMed ID: 20148301
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  • 16. Machupo Virus with Mutations in the Transmembrane Domain and Glycosylation Sites of the Glycoprotein Is Attenuated and Immunogenic in Animal Models of Bolivian Hemorrhagic Fever.
    Mantlo EK, Maruyama J, Manning JT, Wanninger TG, Huang C, Smith JN, Patterson M, Paessler S, Koma T.
    J Virol; 2022 Apr 27; 96(8):e0020922. PubMed ID: 35343792
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  • 17. Attenuation of Chikungunya virus vaccine strain 181/clone 25 is determined by two amino acid substitutions in the E2 envelope glycoprotein.
    Gorchakov R, Wang E, Leal G, Forrester NL, Plante K, Rossi SL, Partidos CD, Adams AP, Seymour RL, Weger J, Borland EM, Sherman MB, Powers AM, Osorio JE, Weaver SC.
    J Virol; 2012 Jun 27; 86(11):6084-96. PubMed ID: 22457519
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  • 18. Rift Valley Fever Virus MP-12 Vaccine Is Fully Attenuated by a Combination of Partial Attenuations in the S, M, and L Segments.
    Ikegami T, Hill TE, Smith JK, Zhang L, Juelich TL, Gong B, Slack OA, Ly HJ, Lokugamage N, Freiberg AN.
    J Virol; 2015 Jul 27; 89(14):7262-76. PubMed ID: 25948740
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  • 19. Protocol for the Production of a Vaccine Against Argentinian Hemorrhagic Fever.
    Ambrosio AM, Mariani MA, Maiza AS, Gamboa GS, Fossa SE, Bottale AJ.
    Methods Mol Biol; 2018 Jul 27; 1604():305-329. PubMed ID: 28986845
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  • 20. Molecular characterization of attenuated Junin virus strains.
    Albariño CG, Ghiringhelli PD, Posik DM, Lozano ME, Ambrosio AM, Sanchez A, Romanowski V.
    J Gen Virol; 1997 Jul 27; 78 ( Pt 7)():1605-10. PubMed ID: 9225036
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