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Journal Abstract Search

182 related items for PubMed ID: 2181322

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  • 3. Substitution of non-catalytic stem and loop regions of hammerhead ribozyme with DNA counterparts only increases KM without sacrificing the catalytic step (kcat): a way to improve substrate-specificity.
    Shimayama T, Sawata S, Komiyama M, Takagi Y, Tanaka Y, Wada A, Sugimoto N, Rossi JJ, Nishikawa F, Nishikawa S.
    Nucleic Acids Symp Ser; 1992; (27):17-8. PubMed ID: 1283905
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  • 8. Model for general acid-base catalysis by the hammerhead ribozyme: pH-activity relationships of G8 and G12 variants at the putative active site.
    Han J, Burke JM.
    Biochemistry; 2005 May 31; 44(21):7864-70. PubMed ID: 15910000
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  • 9. Characterization and divalent metal-ion dependence of in vitro selected deoxyribozymes which cleave DNA/RNA chimeric oligonucleotides.
    Faulhammer D, Famulok M.
    J Mol Biol; 1997 Jun 06; 269(2):188-202. PubMed ID: 9191064
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  • 10. Diffusely bound Mg2+ ions slightly reorient stems I and II of the hammerhead ribozyme to increase the probability of formation of the catalytic core.
    Rueda D, Wick K, McDowell SE, Walter NG.
    Biochemistry; 2003 Aug 26; 42(33):9924-36. PubMed ID: 12924941
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  • 12. Structure and function of the hairpin ribozyme.
    Fedor MJ.
    J Mol Biol; 2000 Mar 24; 297(2):269-91. PubMed ID: 10715200
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  • 15. Efficient improvement of hammerhead ribozyme mediated cleavage of long substrates by oligonucleotide facilitators.
    Jankowsky E, Schwenzer B.
    Biochemistry; 1996 Dec 03; 35(48):15313-21. PubMed ID: 8952482
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  • 16. Chemically modified hammerhead ribozymes with improved catalytic rates.
    Burgin AB, Gonzalez C, Matulic-Adamic J, Karpeisky AM, Usman N, McSwiggen JA, Beigelman L.
    Biochemistry; 1996 Nov 12; 35(45):14090-7. PubMed ID: 8916894
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  • 17. Structure-function relationship of hammerhead ribozymes as probed by 2'-modifications.
    Pieken WA, Olsen DB, Aurup H, Williams DM, Heidenreich O, Benseler F, Eckstein F.
    Nucleic Acids Symp Ser; 1991 Nov 12; (24):51-3. PubMed ID: 1841379
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  • 18. Structural variation induced by different nucleotides at the cleavage site of the hammerhead ribozyme.
    Simorre JP, Legault P, Baidya N, Uhlenbeck OC, Maloney L, Wincott F, Usman N, Beigelman L, Pardi A.
    Biochemistry; 1998 Mar 24; 37(12):4034-44. PubMed ID: 9521724
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  • 19. In vitro evolution suggests multiple origins for the hammerhead ribozyme.
    Salehi-Ashtiani K, Szostak JW.
    Nature; 2001 Nov 01; 414(6859):82-4. PubMed ID: 11689947
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  • 20. Probing general acid catalysis in the hammerhead ribozyme.
    Thomas JM, Perrin DM.
    J Am Chem Soc; 2009 Jan 28; 131(3):1135-43. PubMed ID: 19154176
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