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Journal Abstract Search


168 related items for PubMed ID: 2181495

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  • 2. Enzymatic basis of the debrisoquine/sparteine-type genetic polymorphism of drug oxidation. Characterization of bufuralol 1'-hydroxylation in liver microsomes of in vivo phenotyped carriers of the genetic deficiency.
    Dayer P, Kronbach T, Eichelbaum M, Meyer UA.
    Biochem Pharmacol; 1987 Dec 01; 36(23):4145-52. PubMed ID: 3689440
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  • 4. Xenobiotic and endobiotic inhibitors of cytochrome P-450dbl function, the target of the debrisoquine/sparteine type polymorphism.
    Fonne-Pfister R, Meyer UA.
    Biochem Pharmacol; 1988 Oct 15; 37(20):3829-35. PubMed ID: 2903741
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  • 6. Genetic polymorphism of sparteine/debrisoquine oxidation: a reappraisal.
    Lennard MS.
    Pharmacol Toxicol; 1990 Oct 15; 67(4):273-83. PubMed ID: 2077517
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  • 7. The genetic control of sparteine and debrisoquine metabolism in man with new methods of analysing bimodal distributions.
    Evans DA, Harmer D, Downham DY, Whibley EJ, Idle JR, Ritchie J, Smith RL.
    J Med Genet; 1983 Oct 15; 20(5):321-9. PubMed ID: 6644761
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  • 14. Polymorphic oxidation of sparteine and debrisoquine: related pharmacogenetic entities.
    Eichelbaum M, Bertilsson L, Säwe J, Zekorn C.
    Clin Pharmacol Ther; 1982 Feb 15; 31(2):184-6. PubMed ID: 7056024
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  • 15. Debrisoquine/sparteine hydroxylation genotype and phenotype: analysis of common mutations and alleles of CYP2D6 in a European population.
    Broly F, Gaedigk A, Heim M, Eichelbaum M, Morike K, Meyer UA.
    DNA Cell Biol; 1991 Oct 15; 10(8):545-58. PubMed ID: 1681816
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  • 17. Two mutant alleles of the human cytochrome P-450db1 gene (P450C2D1) associated with genetically deficient metabolism of debrisoquine and other drugs.
    Skoda RC, Gonzalez FJ, Demierre A, Meyer UA.
    Proc Natl Acad Sci U S A; 1988 Jul 15; 85(14):5240-3. PubMed ID: 2899325
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