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284 related items for PubMed ID: 21818319

  • 1. Glutamate-gated chloride channels of Haemonchus contortus restore drug sensitivity to ivermectin resistant Caenorhabditis elegans.
    Glendinning SK, Buckingham SD, Sattelle DB, Wonnacott S, Wolstenholme AJ.
    PLoS One; 2011; 6(7):e22390. PubMed ID: 21818319
    [Abstract] [Full Text] [Related]

  • 2. Caenorhabditis elegans ivermectin receptors regulate locomotor behaviour and are functional orthologues of Haemonchus contortus receptors.
    Cook A, Aptel N, Portillo V, Siney E, Sihota R, Holden-Dye L, Wolstenholme A.
    Mol Biochem Parasitol; 2006 May; 147(1):118-25. PubMed ID: 16527366
    [Abstract] [Full Text] [Related]

  • 3. High-affinity ivermectin binding to recombinant subunits of the Haemonchus contortus glutamate-gated chloride channel.
    Cheeseman CL, Delany NS, Woods DJ, Wolstenholme AJ.
    Mol Biochem Parasitol; 2001 May; 114(2):161-8. PubMed ID: 11378196
    [Abstract] [Full Text] [Related]

  • 4. Genomic organization of an avermectin receptor subunit from Haemonchus contortus and expression of its putative promoter region in Caenorhabditis elegans.
    Liu J, Dent JA, Beech RN, Prichard RK.
    Mol Biochem Parasitol; 2004 Apr; 134(2):267-74. PubMed ID: 15003846
    [Abstract] [Full Text] [Related]

  • 5. Investigating the function and possible biological role of an acetylcholine-gated chloride channel subunit (ACC-1) from the parasitic nematode Haemonchus contortus.
    Callanan MK, Habibi SA, Law WJ, Nazareth K, Komuniecki RL, Forrester SG.
    Int J Parasitol Drugs Drug Resist; 2018 Dec; 8(3):526-533. PubMed ID: 30401619
    [Abstract] [Full Text] [Related]

  • 6. A comparison of the effects of ivermectin and moxidectin on the nematode Caenorhabditis elegans.
    Ardelli BF, Stitt LE, Tompkins JB, Prichard RK.
    Vet Parasitol; 2009 Oct 28; 165(1-2):96-108. PubMed ID: 19631471
    [Abstract] [Full Text] [Related]

  • 7. An ivermectin-sensitive glutamate-gated chloride channel from the parasitic nematode Haemonchus contortus.
    McCavera S, Rogers AT, Yates DM, Woods DJ, Wolstenholme AJ.
    Mol Pharmacol; 2009 Jun 28; 75(6):1347-55. PubMed ID: 19336526
    [Abstract] [Full Text] [Related]

  • 8. Haemonchus contortus: HcGluCla expressed in Xenopus oocytes forms a glutamate-gated ion channel that is activated by ibotenate and the antiparasitic drug ivermectin.
    Forrester SG, Prichard RK, Dent JA, Beech RN.
    Mol Biochem Parasitol; 2003 Jun 28; 129(1):115-21. PubMed ID: 12798512
    [Abstract] [Full Text] [Related]

  • 9. The avermectin receptors of Haemonchus contortus and Caenorhabditis elegans.
    Yates DM, Portillo V, Wolstenholme AJ.
    Int J Parasitol; 2003 Sep 30; 33(11):1183-93. PubMed ID: 13678634
    [Abstract] [Full Text] [Related]

  • 10. Candidate anthelmintic resistance-associated gene expression and sequence polymorphisms in a triple-resistant field isolate of Haemonchus contortus.
    Williamson SM, Storey B, Howell S, Harper KM, Kaplan RM, Wolstenholme AJ.
    Mol Biochem Parasitol; 2011 Dec 30; 180(2):99-105. PubMed ID: 21945142
    [Abstract] [Full Text] [Related]

  • 11. Characterization of glutamate-gated chloride channels in the pharynx of wild-type and mutant Caenorhabditis elegans delineates the role of the subunit GluCl-alpha2 in the function of the native receptor.
    Pemberton DJ, Franks CJ, Walker RJ, Holden-Dye L.
    Mol Pharmacol; 2001 May 30; 59(5):1037-43. PubMed ID: 11306685
    [Abstract] [Full Text] [Related]

  • 12. A new enabling proteomics methodology to investigate membrane associated proteins from parasitic nematodes: case study using ivermectin resistant and ivermectin susceptible isolates of Caenorhabditis elegans and Haemonchus contortus.
    Hart EH, Brophy PM, Prescott M, Bartley DJ, Wolf BT, Hamilton JV.
    Vet Parasitol; 2015 Jan 30; 207(3-4):266-75. PubMed ID: 25537855
    [Abstract] [Full Text] [Related]

  • 13. Two novel loci underlie natural differences in Caenorhabditis elegans abamectin responses.
    Evans KS, Wit J, Stevens L, Hahnel SR, Rodriguez B, Park G, Zamanian M, Brady SC, Chao E, Introcaso K, Tanny RE, Andersen EC.
    PLoS Pathog; 2021 Mar 30; 17(3):e1009297. PubMed ID: 33720993
    [Abstract] [Full Text] [Related]

  • 14. Evidence from two independent backcross experiments supports genetic linkage of microsatellite Hcms8a20, but not other candidate loci, to a major ivermectin resistance locus in Haemonchus contortus.
    Rezansoff AM, Laing R, Gilleard JS.
    Int J Parasitol; 2016 Sep 30; 46(10):653-61. PubMed ID: 27216082
    [Abstract] [Full Text] [Related]

  • 15. Isolation and characterization of a novel member of the ACC ligand-gated chloride channel family, Hco-LCG-46, from the parasitic nematode Haemonchus contortus.
    Habibi SA, Blazie SM, Jin Y, Forrester SG.
    Mol Biochem Parasitol; 2020 May 30; 237():111276. PubMed ID: 32268182
    [Abstract] [Full Text] [Related]

  • 16. The genetics of ivermectin resistance in Caenorhabditis elegans.
    Dent JA, Smith MM, Vassilatis DK, Avery L.
    Proc Natl Acad Sci U S A; 2000 Mar 14; 97(6):2674-9. PubMed ID: 10716995
    [Abstract] [Full Text] [Related]

  • 17. Haemonchus contortus: selection at a glutamate-gated chloride channel gene in ivermectin- and moxidectin-selected strains.
    Blackhall WJ, Pouliot JF, Prichard RK, Beech RN.
    Exp Parasitol; 1998 Sep 14; 90(1):42-8. PubMed ID: 9709029
    [Abstract] [Full Text] [Related]

  • 18. avr-15 encodes a chloride channel subunit that mediates inhibitory glutamatergic neurotransmission and ivermectin sensitivity in Caenorhabditis elegans.
    Dent JA, Davis MW, Avery L.
    EMBO J; 1997 Oct 01; 16(19):5867-79. PubMed ID: 9312045
    [Abstract] [Full Text] [Related]

  • 19. Cloning and characterization of genes encoding alpha and beta subunits of glutamate-gated chloride channel protein in Cylicocyclus nassatus.
    Tandon R, LePage KT, Kaplan RM.
    Mol Biochem Parasitol; 2006 Nov 01; 150(1):46-55. PubMed ID: 16872692
    [Abstract] [Full Text] [Related]

  • 20. Functional reconstitution of Haemonchus contortus acetylcholine receptors in Xenopus oocytes provides mechanistic insights into levamisole resistance.
    Boulin T, Fauvin A, Charvet CL, Cortet J, Cabaret J, Bessereau JL, Neveu C.
    Br J Pharmacol; 2011 Nov 01; 164(5):1421-32. PubMed ID: 21486278
    [Abstract] [Full Text] [Related]

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