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165 related items for PubMed ID: 21819071

  • 1. ²H kinetic isotope effects and pH dependence of catalysis as mechanistic probes of rat monoamine oxidase A: comparisons with the human enzyme.
    Wang J, Edmondson DE.
    Biochemistry; 2011 Sep 06; 50(35):7710-7. PubMed ID: 21819071
    [Abstract] [Full Text] [Related]

  • 2. Structure-activity relationships in the oxidation of para-substituted benzylamine analogues by recombinant human liver monoamine oxidase A.
    Miller JR, Edmondson DE.
    Biochemistry; 1999 Oct 12; 38(41):13670-83. PubMed ID: 10521274
    [Abstract] [Full Text] [Related]

  • 3. Structure-activity relations in the oxidation of phenethylamine analogues by recombinant human liver monoamine oxidase A.
    Nandigama RK, Edmondson DE.
    Biochemistry; 2000 Dec 12; 39(49):15258-65. PubMed ID: 11106506
    [Abstract] [Full Text] [Related]

  • 4. Structure-activity relationships in the oxidation of benzylamine analogues by bovine liver mitochondrial monoamine oxidase B.
    Walker MC, Edmondson DE.
    Biochemistry; 1994 Jun 14; 33(23):7088-98. PubMed ID: 8003474
    [Abstract] [Full Text] [Related]

  • 5. Aminium cation radical mechanism proposed for monoamine oxidase B catalysis: are there alternatives?
    Edmondson DE.
    Xenobiotica; 1995 Jul 14; 25(7):735-53. PubMed ID: 7483670
    [Abstract] [Full Text] [Related]

  • 6. Loss of serotonin oxidation as a component of the altered substrate specificity in the Y444F mutant of recombinant human liver MAO A.
    Nandigama RK, Miller JR, Edmondson DE.
    Biochemistry; 2001 Dec 11; 40(49):14839-46. PubMed ID: 11732903
    [Abstract] [Full Text] [Related]

  • 7. Evidence for alternative binding modes in the interaction of benzylamine analogues with bovine liver monoamine oxidase B.
    Edmondson DE, Bhattacharrya AK, Xu J.
    Biochim Biophys Acta; 2000 Jun 15; 1479(1-2):52-8. PubMed ID: 11004529
    [Abstract] [Full Text] [Related]

  • 8. Structure activity studies of the substrate binding site in monoamine oxidase B.
    Edmondson DE.
    Biochimie; 1995 Jun 15; 77(7-8):643-50. PubMed ID: 8589074
    [Abstract] [Full Text] [Related]

  • 9. Catalytic and inhibitor binding properties of zebrafish monoamine oxidase (zMAO): comparisons with human MAO A and MAO B.
    Aldeco M, Arslan BK, Edmondson DE.
    Comp Biochem Physiol B Biochem Mol Biol; 2011 Jun 15; 159(2):78-83. PubMed ID: 21354322
    [Abstract] [Full Text] [Related]

  • 10. High-level expression of human liver monoamine oxidase B in Pichia pastoris.
    Newton-Vinson P, Hubalek F, Edmondson DE.
    Protein Expr Purif; 2000 Nov 15; 20(2):334-45. PubMed ID: 11049757
    [Abstract] [Full Text] [Related]

  • 11. Path Integral Calculation of the Hydrogen/Deuterium Kinetic Isotope Effect in Monoamine Oxidase A-Catalyzed Decomposition of Benzylamine.
    Brela MZ, Prah A, Boczar M, Stare J, Mavri J.
    Molecules; 2019 Nov 28; 24(23):. PubMed ID: 31795294
    [Abstract] [Full Text] [Related]

  • 12. Do MAO A and MAO B utilize the same mechanism for the C-H bond cleavage step in catalysis? Evidence suggesting differing mechanisms.
    Orru R, Aldeco M, Edmondson DE.
    J Neural Transm (Vienna); 2013 Jun 28; 120(6):847-51. PubMed ID: 23417310
    [Abstract] [Full Text] [Related]

  • 13. Deuterium isotope effects for the oxidation of 1-methyl-3-phenyl-3-pyrrolinyl analogues by monoamine oxidase B.
    Pretorius A, Ogunrombi MO, Terre'blanche G, Castagnoli N, Bergh JJ, Petzer JP.
    Bioorg Med Chem; 2008 Oct 01; 16(19):8813-7. PubMed ID: 18799315
    [Abstract] [Full Text] [Related]

  • 14. Studies of the enzymic mechanism of Candida tenuis xylose reductase (AKR 2B5): X-ray structure and catalytic reaction profile for the H113A mutant.
    Kratzer R, Kavanagh KL, Wilson DK, Nidetzky B.
    Biochemistry; 2004 May 04; 43(17):4944-54. PubMed ID: 15109252
    [Abstract] [Full Text] [Related]

  • 15. Acid-base catalysis by UDP-galactose 4-epimerase: correlations of kinetically measured acid dissociation constants with thermodynamic values for tyrosine 149.
    Berger E, Arabshahi A, Wei Y, Schilling JF, Frey PA.
    Biochemistry; 2001 Jun 05; 40(22):6699-705. PubMed ID: 11380265
    [Abstract] [Full Text] [Related]

  • 16. Examining the relative timing of hydrogen abstraction steps during NAD(+)-dependent oxidation of secondary alcohols catalyzed by long-chain D-mannitol dehydrogenase from Pseudomonas fluorescens using pH and kinetic isotope effects.
    Klimacek M, Nidetzky B.
    Biochemistry; 2002 Aug 06; 41(31):10158-65. PubMed ID: 12146981
    [Abstract] [Full Text] [Related]

  • 17. Variations in activity and inhibition with pH: the protonated amine is the substrate for monoamine oxidase, but uncharged inhibitors bind better.
    Jones TZ, Balsa D, Unzeta M, Ramsay RR.
    J Neural Transm (Vienna); 2007 Aug 06; 114(6):707-12. PubMed ID: 17401535
    [Abstract] [Full Text] [Related]

  • 18. The pH dependence of kinetic isotope effects in monoamine oxidase A indicates stabilization of the neutral amine in the enzyme-substrate complex.
    Dunn RV, Marshall KR, Munro AW, Scrutton NS.
    FEBS J; 2008 Aug 06; 275(15):3850-8. PubMed ID: 18573102
    [Abstract] [Full Text] [Related]

  • 19. Reaction of vascular adhesion protein-1 (VAP-1) with primary amines: mechanistic insights from isotope effects and quantitative structure-activity relationships.
    Heuts DP, Gummadova JO, Pang J, Rigby SE, Scrutton NS.
    J Biol Chem; 2011 Aug 26; 286(34):29584-93. PubMed ID: 21737458
    [Abstract] [Full Text] [Related]

  • 20. High-level expression and purification of rat monoamine oxidase A (MAO A) in Pichia pastoris: comparison with human MAO A.
    Wang J, Edmondson DE.
    Protein Expr Purif; 2010 Apr 26; 70(2):211-7. PubMed ID: 19883764
    [Abstract] [Full Text] [Related]

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