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Journal Abstract Search

138 related items for PubMed ID: 21821420

  • 1. Synthesis and in vivo evaluation of [O-methyl-11C] N-[3,5-dichloro-2-(methoxy)phenyl]-4-(methoxy)-3-(1-piperazinyl)benzenesulfonamide as an imaging probe for 5-HT6 receptors.
    Liu F, Majo VJ, Prabhakaran J, Milak MS, John Mann J, Parsey RV, Kumar JS.
    Bioorg Med Chem; 2011 Sep 01; 19(17):5255-9. PubMed ID: 21821420
    [Abstract] [Full Text] [Related]

  • 2. Synthesis and in vivo evaluation of [O-methyl-11C](2R,4R)-4-hydroxy-2-[2-[2-[2-(3-methoxy)phenyl]ethyl]phenoxy]ethyl-1-methylpyrrolidine as a 5-HT2A receptor PET ligand.
    Kumar JS, Prabhakaran J, Erlandsson K, Majo VJ, Simpson NR, Pratap M, Van Heertum RL, Mann JJ, Parsey RV.
    Nucl Med Biol; 2006 May 01; 33(4):565-74. PubMed ID: 16720250
    [Abstract] [Full Text] [Related]

  • 3. Synthesis and evaluation of 1-[2-(4-[(11)C]methoxyphenyl)phenyl]piperazine for imaging of the serotonin 5-HT7 receptor in the rat brain.
    Shimoda Y, Yui J, Xie L, Fujinaga M, Yamasaki T, Ogawa M, Nengaki N, Kumata K, Hatori A, Kawamura K, Zhang MR.
    Bioorg Med Chem; 2013 Sep 01; 21(17):5316-22. PubMed ID: 23830697
    [Abstract] [Full Text] [Related]

  • 4. Synthesis of carbon-11-labeled 5-HT6R antagonists as new candidate PET radioligands for imaging of Alzheimer's disease.
    Wang X, Dong F, Miao C, Li W, Wang M, Gao M, Zheng QH, Xu Z.
    Bioorg Med Chem Lett; 2018 Jun 01; 28(10):1836-1841. PubMed ID: 29661535
    [Abstract] [Full Text] [Related]

  • 5. Synthesis and initial evaluation of [11C](R)-RWAY in monkey-a new, simply labeled antagonist radioligand for imaging brain 5-HT1A receptors with PET.
    McCarron JA, Zoghbi SS, Shetty HU, Vermeulen ES, Wikström HV, Ichise M, Yasuno F, Halldin C, Innis RB, Pike VW.
    Eur J Nucl Med Mol Imaging; 2007 Oct 01; 34(10):1670-82. PubMed ID: 17579853
    [Abstract] [Full Text] [Related]

  • 6. Indole-3-piperazinyl derivatives: novel chemical class of 5-HT(6) receptor antagonists.
    Nirogi RV, Deshpande AD, Kambhampati R, Badange RK, Kota L, Daulatabad AV, Shinde AK, Ahmad I, Kandikere V, Jayarajan P, Dubey PK.
    Bioorg Med Chem Lett; 2011 Jan 01; 21(1):346-9. PubMed ID: 21134749
    [Abstract] [Full Text] [Related]

  • 7. New halogenated [11C]WAY analogues, [11C]6FPWAY and [11C]6BPWAY--radiosynthesis and assessment as radioligands for the study of brain 5-HT1A receptors in living monkey.
    Sandell J, Halldin C, Pike VW, Chou YH, Varnäs K, Hall H, Marchais S, Nowicki B, Wikström HV, Swahn CG, Farde L.
    Nucl Med Biol; 2001 Feb 01; 28(2):177-85. PubMed ID: 11295428
    [Abstract] [Full Text] [Related]

  • 8. Radiosynthesis and in vivo evaluation of novel radioligands for PET imaging of cerebral 5-HT7 receptors.
    Hansen HD, Herth MM, Ettrup A, Andersen VL, Lehel S, Dyssegaard A, Kristensen JL, Knudsen GM.
    J Nucl Med; 2014 Apr 01; 55(4):640-6. PubMed ID: 24566002
    [Abstract] [Full Text] [Related]

  • 9. Synthesis and biologic evaluation of a novel serotonin 5-HT1A receptor radioligand, 18F-labeled mefway, in rodents and imaging by PET in a nonhuman primate.
    Saigal N, Pichika R, Easwaramoorthy B, Collins D, Christian BT, Shi B, Narayanan TK, Potkin SG, Mukherjee J.
    J Nucl Med; 2006 Oct 01; 47(10):1697-706. PubMed ID: 17015907
    [Abstract] [Full Text] [Related]

  • 10. Phenyl benzenesulfonamides are novel and selective 5-HT6 antagonists: identification of N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-piperazin-1-ylbenzenesulfonamide (SB-357134).
    Bromidge SM, Clarke SE, Gager T, Griffith K, Jeffrey P, Jennings AJ, Joiner GF, King FD, Lovell PJ, Moss SF, Newman H, Riley G, Rogers D, Routledge C, Serafinowska H, Smith DR.
    Bioorg Med Chem Lett; 2001 Jan 08; 11(1):55-8. PubMed ID: 11140733
    [Abstract] [Full Text] [Related]

  • 11. Synthesis and evaluation of [¹¹C]Cimbi-806 as a potential PET ligand for 5-HT₇ receptor imaging.
    Herth MM, Hansen HD, Ettrup A, Dyssegaard A, Lehel S, Kristensen J, Knudsen GM.
    Bioorg Med Chem; 2012 Jul 15; 20(14):4574-81. PubMed ID: 22682922
    [Abstract] [Full Text] [Related]

  • 12. The PET radioligand [carbonyl-(11)C]desmethyl-WAY-100635 binds to 5-HT(1A) receptors and provides a higher radioactive signal than [carbonyl-(11)C]WAY-100635 in the human brain.
    Andrée B, Halldin C, Pike VW, Gunn RN, Olsson H, Farde L.
    J Nucl Med; 2002 Mar 15; 43(3):292-303. PubMed ID: 11884487
    [Abstract] [Full Text] [Related]

  • 13. Characterisation of the appearance of radioactive metabolites in monkey and human plasma from the 5-HT1A receptor radioligand, [carbonyl-11C]WAY-100635--explanation of high signal contrast in PET and an aid to biomathematical modelling.
    Osman S, Lundkvist C, Pike VW, Halldin C, McCarron JA, Swahn CG, Farde L, Ginovart N, Luthra SK, Gunn RN, Bench CJ, Sargent PA, Grasby PM.
    Nucl Med Biol; 1998 Apr 15; 25(3):215-23. PubMed ID: 9620626
    [Abstract] [Full Text] [Related]

  • 14. Synthesis, radiolabeling and in vivo evaluation of [(11)C](R)-1-[4-[2-(4-methoxyphenyl)phenyl]piperazin-1-yl]-3-(2-pyrazinyloxy)-2-propanol, a potential PET radioligand for the 5-HT(7) receptor.
    Hansen HD, Lacivita E, Di Pilato P, Herth MM, Lehel S, Ettrup A, Andersen VL, Dyssegaard A, De Giorgio P, Perrone R, Berardi F, Colabufo NA, Niso M, Knudsen GM, Leopoldo M.
    Eur J Med Chem; 2014 May 22; 79():152-63. PubMed ID: 24732791
    [Abstract] [Full Text] [Related]

  • 15. Current status of positron emission tomography radiotracers for serotonin receptors in humans.
    Zimmer L, Le Bars D.
    J Labelled Comp Radiopharm; 2013 May 22; 56(3-4):105-13. PubMed ID: 24285316
    [Abstract] [Full Text] [Related]

  • 16. SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models.
    Hirst WD, Stean TO, Rogers DC, Sunter D, Pugh P, Moss SF, Bromidge SM, Riley G, Smith DR, Bartlett S, Heidbreder CA, Atkins AR, Lacroix LP, Dawson LA, Foley AG, Regan CM, Upton N.
    Eur J Pharmacol; 2006 Dec 28; 553(1-3):109-19. PubMed ID: 17069795
    [Abstract] [Full Text] [Related]

  • 17. The new PET imaging agent [11C]AFE is a selective serotonin transporter ligand with fast brain uptake kinetics.
    Zhu Z, Guo N, Narendran R, Erritzoe D, Ekelund J, Hwang DR, Bae SA, Laruelle M, Huang Y.
    Nucl Med Biol; 2004 Nov 28; 31(8):983-94. PubMed ID: 15607480
    [Abstract] [Full Text] [Related]

  • 18. 11C-labeling of n-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butyl]arylcarboxamide derivatives and evaluation as potential radioligands for PET imaging of dopamine D3 receptors.
    Turolla EA, Matarrese M, Belloli S, Moresco RM, Simonelli P, Todde S, Fazio F, Magni F, Kienle MG, Leopoldo M, Berardi F, Colabufo NA, Lacivita E, Perrone R.
    J Med Chem; 2005 Nov 03; 48(22):7018-23. PubMed ID: 16250661
    [Abstract] [Full Text] [Related]

  • 19. Synthesis and in vivo evaluation of novel PET radioligands for imaging the endothelin-A receptor.
    Mathews WB, Murugesan N, Xia J, Scheffel U, Hilton J, Ravert HT, Dannals RF, Szabo Z.
    J Nucl Med; 2008 Sep 03; 49(9):1529-36. PubMed ID: 18703610
    [Abstract] [Full Text] [Related]

  • 20. Synthesis and positron emission tomography studies of C-11-labeled isotopomers and metabolites of GTS-21, a partial alpha7 nicotinic cholinergic agonist drug.
    Kim SW, Ding YS, Alexoff D, Patel V, Logan J, Lin KS, Shea C, Muench L, Xu Y, Carter P, King P, Constanzo JR, Ciaccio JA, Fowler JS.
    Nucl Med Biol; 2007 Jul 03; 34(5):541-51. PubMed ID: 17591554
    [Abstract] [Full Text] [Related]

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